Navigation Links
Mix of Genetics and Stress Can Impair Mental Abilities
Date:3/7/2011

MONDAY, March 7 (HealthDay News) -- Genetics may predispose some people who live in so-called "hazardous" neighborhoods -- where fear and stress are a fact of daily life -- to face a higher risk for age-related cognitive decline, new research warns.

The culprit is a specific abnormality of the apolipoprotein E gene. The study authors noted that while this gene is known to play a key role in the normal maintenance of basic neurological health, a certain mutation of this gene has also previously been linked to a higher risk for the early onset of Alzheimer's disease.

Now a team of researchers led by Brian K. Lee, of Drexel University in Philadelphia, has found that those carrying the mutation may also face a higher risk for cognitive impairment when they get older, if they live in the kind of threatening environment that routinely elicits "a biological stress response."

The observation is reported in the March issue of the Archives of General Psychiatry.

The new finding stems from an analysis of mental health data collected during the Baltimore Memory Study, which involved more than 1,100 urban residents living in 63 Baltimore neighborhoods.

All of the study participants were between the ages of 50 and 70. About 54 percent were white; nearly 42 percent were black.

As a whole, 30 percent were found to carry at least one mutation of the gene in question, the researchers found. However, blacks were more likely to carry the mutation than whites (37.3 percent versus 24.7 percent, respectively).

Genetics, in fact, wasn't the sole determinant of how well a person performed on cognitive tests. Any participant living in a stress-inducing environment, regardless of whether they possessed the mutation in question, performed "substantially" worse on the series of tests, which among other things included a focus on language skills, verbal memory and learning, eye-hand coordination and visual memory.

What's more, among those without the telltale mutation, those living in relatively more hazardous neighborhoods performed no worse on cognitive testing than those living in better neighborhoods. And among those with the mutation, those living in relatively better conditions executed the test skills equally well as those without the mutation, according to the study authors.

However, Lee's team found that those who carried the mutation, and also lived in neighborhoods characterized as the most psychosocially hazardous, performed the worst in terms of cognitive skills such as eye-hand coordination, task execution, processing speed and visual-spatial abilities.

More information

For more on mental health, visit the U.S. National Institute of Mental Health.

-- Alan Mozes

SOURCE: Archives of General Psychiatry, news release, March 7, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Interleukin Genetics, Inc. and Stanford University Report Genetic Test Improves Weight Loss Success With Diets
2. Study finds changes in fetal epigenetics throughout pregnancy
3. Genetics, Psychology May Trigger ADHD
4. Resveratrol Supplement Company RevGenetics Welcomes New Chief Science Officer
5. Mount Sinai School of Medicine Commencement Honors Leaders in Genetics and Global Health
6. Cancer genetics pioneer wins Margaret Kripke Legend Award
7. Genetics of childrens brain tumor unlocked
8. Existence Genetics is Pioneering the Field of Predictive Medicine - Nexus Technologies Critical in Understanding and Preventing Deadly Disease
9. Genetics, Insecticides Might Contribute to Parkinsons
10. Can I buy you a drink? Genetics may determine sensitivity to other peoples drinking behavior
11. Perspectives on improving patient care: Genetics, personalized medicine, and behavioral intervention
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mix of Genetics and Stress Can Impair Mental Abilities
(Date:2/24/2017)... ... February 24, 2017 , ... WHAT: ... networking and recognition opportunities as well as advocacy for the state and region‘s ... on February 23. The Council's Innovation Forecast event highlights innovation throughout the ...
(Date:2/24/2017)... ... , ... With millions of Americans and people worldwide struggling ... are aware of our options and are empowered with strength and information throughout ... its newest edition of "Vision and Hearing" in USA Today, that will educate ...
(Date:2/24/2017)... , ... February 24, 2017 , ... Yisrayl Hawkins, Pastor ... on Bible Prophecy concerning this present generation. Yisrayl makes an astounding statement when ... generation. He explains that the Bible details the current times so plainly that ...
(Date:2/24/2017)... ... February 24, 2017 , ... Congratulations to ... Elite division on February 12th. Ms. Esparza qualified into this prestigious status ... competition held in Las Vegas, Nevada. Frida is one of approximately 25 gymnasts ...
(Date:2/23/2017)... ... February 23, 2017 , ... ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... the La Gorce Country Club in Miami Beach to host its Swirl: Miami ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... YORK , Feb. 23, 2017  The ... 330.6 million by 2021 from USD 275.9 million ... Read the full report: http://www.reportlinker.com/p04718602-summary/view-report.html ... increasing spending on pharmaceutical R&D, and growth in ... driving the market growth for particle counters. On ...
(Date:2/23/2017)... , Feb 23, 2017 Research and Markets ... Price Analysis and Strategies - 2016" report to their offering. ... The latest ... provides drug pricing data and benchmarks in the global Autism Spectrum ... What are the key drugs marketed for Autism ...
(Date:2/23/2017)... CITY, Calif., Feb. 23, 2017 Nevro Corp. (NYSE: ... evidence-based solutions for the treatment of chronic pain, today reported ... December 31, 2016. 2016 Accomplishment & Highlights: ... full year 2016, an increase of 228% as reported, over ... for 2016, an increase of 612% over the prior year ...
Breaking Medicine Technology: