Navigation Links
Mitosis gets harder thanks to new gene discovery

A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery published today.

Scientists from the University of Bath have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

In research published in the journal Molecular Biology of the Cell, the scientists have shown that the protein is essential for building the microtubules that allow the two halves of the cell to slide apart.

What makes mitosis so interesting is that it is one of the biological processes that everyone remembers from their days at school, said Dr Andrew Chalmers from the Universitys Department of Biology & Biochemistry.

As well as being one of Natures most important processes, our interest in mitosis stems from the fact that if you want to kill cancer cells, then stopping them from dividing is a useful way of doing this.

Several cancer treatments block cell division by targeting microtubules, Taxol is a well known example. It is even possible that RASSF7 might be a future drug target.

During the different phases of mitosis the pairs of chromosomes within the cell condense and attach to microtubule fibres that pull the sister chromatids to opposite sides of the cell.

The cell then divides in cytokinesis, to produce two identical daughter cells.

RASSF7 is the latest of a battery of proteins involved in managing the complex process of mitosis.

During mitosis, the chromosomes containing the DNA are pulled apart in two halves by an array of microtubules centred on the centrosomes, said Dr Chalmers.

Without the RASSF7 protein, the microtubules do not develop properly and cell division is halted.

This is the first functional study of this protein, and we hope to extend our knowledge of how it works in the future.

The research was funded by the Medical Research Council.

The work was carried out in Dr Chalmers laboratory by Dr Victoria Sherwood and two final year undergraduate project students from the University, Ria Manbodh and Carol Sheppard.

Dr Sherwood will now continue her research on cancer at a new job at the Lund University Clinical Research Centre, Sweden.


Contact: Andrew McLaughlin
University of Bath

Related medicine news :

1. Dementia in More Educated Hits Later But Harder
2. Vincent Corso and Daniel Trush Win 2007 Avis We Try Harder Awards
3. Studies Reveal Why Breast Cancer Hits Black Women Harder
4. Survey Says: Patients Prep Harder for Vacation than for an Operation
5. Digest This: Digestive Health Harder to Maintain Than Financial Health
6. Older Women Have Harder Time Preserving Muscle Than Men
7. Long Term Care Insurance Gains Momentum Thanks to State Promotions, a Leading Brokerage Reports
8. 600 Smiles Restored Thanks to the AACDCFs Give Back A Smile Program - October Marks National Domestic Violence Awareness Month
9. World Health Organization thanks CBM For their outstanding work
10. Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca
11. Its More Than the Turkey Dinner That Will Leave You Feeling Bloated This Thanksgiving
Post Your Comments:
(Date:11/27/2015)... ... 2015 , ... "When I was traveling, I was very ... "Many people catch diseases simply from sitting on such dirty toilet seats. I ... germs." , He developed the patent-pending QUDRATECS to eliminate the need to sit ...
(Date:11/27/2015)... Fairfax, VVA (PRWEB) , ... November 27, 2015 ... ... (RBMA) motto of progress through sharing, the 2016 Building Better Radiology ... campaigns. The conference will begin on Sunday, March 6, 2016, at Caesars Palace ...
(Date:11/27/2015)... ... ... CBD College is proud to announce that on November 20th, ... its Diagnostic Medical Sonography program. CBD College is honored to join this very short ... universities in the state of California make the cut. CBD College is officially the ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... located in central Michigan, have come together on Thanksgiving Day to share the ... available for viewing on the Serenity Point YouTube channel, patients displayed what they ...
(Date:11/26/2015)... ... , ... Jobs in hospital medical laboratories and in the imaging field lead ... Aureus Medical Group . These fields, as well as travel nursing, ... healthcare jobs through the company’s website, , The leading healthcare staffing ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... Nov. 26, 2015 ... of the "2016 Global Tumor Marker ... Volume and Sales Segment Forecasts, Innovative Technologies, ... report to their offering. --> ... the "2016 Global Tumor Marker Testing ...
(Date:11/26/2015)... WILMINGTON, North Carolina , 26 november ... Laboratories, Inc. (AAIPharma/CML) kondigt de geplande investering ... de uitbreiding van de laboratoria en het ... . De uitbreiding zal resulteren in ... waarmee wordt voldaan aan de groeiende behoeften ...
(Date:11/26/2015)... STOCKHOLM , November 26, 2015 ... the potential to use SyMRI to find optimal contrast weighting ... brain tumor metastases, and has signed a research agreement with ... at the hospital. Using SyMRI, it is possible to generate ... parameter settings after the patient has left, thus making it ...
Breaking Medicine Technology: