Navigation Links
Mitosis gets harder thanks to new gene discovery
Date:4/3/2008

A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery published today.

Scientists from the University of Bath have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

In research published in the journal Molecular Biology of the Cell, the scientists have shown that the protein is essential for building the microtubules that allow the two halves of the cell to slide apart.

What makes mitosis so interesting is that it is one of the biological processes that everyone remembers from their days at school, said Dr Andrew Chalmers from the Universitys Department of Biology & Biochemistry.

As well as being one of Natures most important processes, our interest in mitosis stems from the fact that if you want to kill cancer cells, then stopping them from dividing is a useful way of doing this.

Several cancer treatments block cell division by targeting microtubules, Taxol is a well known example. It is even possible that RASSF7 might be a future drug target.

During the different phases of mitosis the pairs of chromosomes within the cell condense and attach to microtubule fibres that pull the sister chromatids to opposite sides of the cell.

The cell then divides in cytokinesis, to produce two identical daughter cells.

RASSF7 is the latest of a battery of proteins involved in managing the complex process of mitosis.

During mitosis, the chromosomes containing the DNA are pulled apart in two halves by an array of microtubules centred on the centrosomes, said Dr Chalmers.

Without the RASSF7 protein, the microtubules do not develop properly and cell division is halted.

This is the first functional study of this protein, and we hope to extend our knowledge of how it works in the future.

The research was funded by the Medical Research Council.

The work was carried out in Dr Chalmers laboratory by Dr Victoria Sherwood and two final year undergraduate project students from the University, Ria Manbodh and Carol Sheppard.

Dr Sherwood will now continue her research on cancer at a new job at the Lund University Clinical Research Centre, Sweden.


'/>"/>

Contact: Andrew McLaughlin
press@bath.ac.uk
44-012-253-86883
University of Bath
Source:Eurekalert

Related medicine news :

1. Dementia in More Educated Hits Later But Harder
2. Vincent Corso and Daniel Trush Win 2007 Avis We Try Harder Awards
3. Studies Reveal Why Breast Cancer Hits Black Women Harder
4. Survey Says: Patients Prep Harder for Vacation than for an Operation
5. Digest This: Digestive Health Harder to Maintain Than Financial Health
6. Older Women Have Harder Time Preserving Muscle Than Men
7. Long Term Care Insurance Gains Momentum Thanks to State Promotions, a Leading Brokerage Reports
8. 600 Smiles Restored Thanks to the AACDCFs Give Back A Smile Program - October Marks National Domestic Violence Awareness Month
9. World Health Organization thanks CBM For their outstanding work
10. Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca
11. Its More Than the Turkey Dinner That Will Leave You Feeling Bloated This Thanksgiving
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... 10, 2016 , ... Everseat has joined the award-winning Allscripts ... physicians. The integration will enable Allscripts users to post open appointments to the ... app. , The partnership gives Everseat substantial added power to help Allscripts meet ...
(Date:2/10/2016)... ... February 10, 2016 , ... Workrite Ergonomics, who is celebrating their 25th ... humble beginnings to being an internationally recognized leader in their industry. , "We are ... Charlie Lawrence, President of Workrite. “Workrite recognized the importance of good ergonomics before ...
(Date:2/10/2016)... ... February 09, 2016 , ... Western University ... free oral screenings to 150 children in kindergarten through third grade at Hurley ... Dental Medicine joined Chinese American Dental Society of Southern California volunteers for Give ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... It’s that ... Traci Davis, the new president of the Interscholastic Athletic Association of Maryland (IAAM), Hall ... well how quickly fitness goals are cast aside. , That’s why one of her ...
(Date:2/9/2016)... ... , ... February is Heart Awareness Month, and to celebrate Health Quest Chiropractic ... the American Heart Association, New Mexico chapter. , A Heart Rate Variability (HRV) scan ... INSiGHT Pulse Wave Profiler utilizes a non-invasive technology to determine a heart’s ability to ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... Mass. , Feb. 9, 2016   AllCare ... The Joint Commission,s Gold Seal of Approval ® ... compliance with its performance standards. The Gold Seal of ... reflects an organization,s commitment to providing safe and effective ... AllCare Plus Pharmacy underwent a rigorous on-site survey ...
(Date:2/9/2016)... The global prefilled syringes market accounted for $3,905.1 million ... with a CAGR of 12.9% during 2015-2020. Among the ... global prefilled syringes market, with 90.1% share in 2014. ... global market of prefilled syringes is up surging with ... demand for vaccines, increasing prevalence of chronic and lifestyle ...
(Date:2/9/2016)... Calif. , Feb. 9, 2016  Increasingly, health ... monitoring their vital signs with wireless technology. With the ... can automate patient oversight and remotely detect problems before ... vital signs across in-hospital environments. the ... the United States . --> ...
Breaking Medicine Technology: