Navigation Links
Mitosis gets harder thanks to new gene discovery
Date:4/3/2008

A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery published today.

Scientists from the University of Bath have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

In research published in the journal Molecular Biology of the Cell, the scientists have shown that the protein is essential for building the microtubules that allow the two halves of the cell to slide apart.

What makes mitosis so interesting is that it is one of the biological processes that everyone remembers from their days at school, said Dr Andrew Chalmers from the Universitys Department of Biology & Biochemistry.

As well as being one of Natures most important processes, our interest in mitosis stems from the fact that if you want to kill cancer cells, then stopping them from dividing is a useful way of doing this.

Several cancer treatments block cell division by targeting microtubules, Taxol is a well known example. It is even possible that RASSF7 might be a future drug target.

During the different phases of mitosis the pairs of chromosomes within the cell condense and attach to microtubule fibres that pull the sister chromatids to opposite sides of the cell.

The cell then divides in cytokinesis, to produce two identical daughter cells.

RASSF7 is the latest of a battery of proteins involved in managing the complex process of mitosis.

During mitosis, the chromosomes containing the DNA are pulled apart in two halves by an array of microtubules centred on the centrosomes, said Dr Chalmers.

Without the RASSF7 protein, the microtubules do not develop properly and cell division is halted.

This is the first functional study of this protein, and we hope to extend our knowledge of how it works in the future.

The research was funded by the Medical Research Council.

The work was carried out in Dr Chalmers laboratory by Dr Victoria Sherwood and two final year undergraduate project students from the University, Ria Manbodh and Carol Sheppard.

Dr Sherwood will now continue her research on cancer at a new job at the Lund University Clinical Research Centre, Sweden.


'/>"/>

Contact: Andrew McLaughlin
press@bath.ac.uk
44-012-253-86883
University of Bath
Source:Eurekalert

Related medicine news :

1. Dementia in More Educated Hits Later But Harder
2. Vincent Corso and Daniel Trush Win 2007 Avis We Try Harder Awards
3. Studies Reveal Why Breast Cancer Hits Black Women Harder
4. Survey Says: Patients Prep Harder for Vacation than for an Operation
5. Digest This: Digestive Health Harder to Maintain Than Financial Health
6. Older Women Have Harder Time Preserving Muscle Than Men
7. Long Term Care Insurance Gains Momentum Thanks to State Promotions, a Leading Brokerage Reports
8. 600 Smiles Restored Thanks to the AACDCFs Give Back A Smile Program - October Marks National Domestic Violence Awareness Month
9. World Health Organization thanks CBM For their outstanding work
10. Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca
11. Its More Than the Turkey Dinner That Will Leave You Feeling Bloated This Thanksgiving
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... August 22, 2017 , ... Five Star Glass is new to the Texas market, but ... of auto glass for most makes and models, in Grand Prairie, TX, located in the ... They have been a family owned business for the past 40 years with 32 convenient ...
(Date:8/22/2017)... ... , ... “Glimpses Of Light”: is a unique and thought inspiring guide ... creation of published author, J.M. Shepherd, a writer, teacher, traveler, and metaphysician, the author ... , Shepherd shares, “Love is one of the least understood and yet most sought-after ...
(Date:8/21/2017)... MO (PRWEB) , ... August 22, 2017 , ... PracticeMatch, ... fairs to help healthcare employers connect with physicians and advanced practitioners like nurse ... virtual career fairs in August through November of this year. The online career ...
(Date:8/21/2017)... ... 2017 , ... SportsEngine, Inc. , a division of ... of North Country Region Volleyball and will power registration, scheduling, and competition results ... sport management software to their member clubs. , SportsEngine provides financial ...
(Date:8/21/2017)... ... , ... PIXACORE , an independent full-service agency with a decade of ... the year by MM&M. , This is the first time PIXACORE has made the ... agency. PIXACORE’s newfound recognition reflects its steady trajectory of growth and recent strategic ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... 2017 Three Tru-D SmartUVC robots have arrived at ... . Tru-D, short for "Total Room Ultraviolet Disinfection," is a 5-foot-5 ... environmental services (ES) professional cleans the area with traditional cleaning protocols. ... Tru-D fights germs at ... "Although the BAACH has a very low ...
(Date:7/27/2017)... 27, 2017  Zimmer Biomet Holdings, Inc. (NYSE and ... June 30, 2017.  The Company reported second quarter net ... the prior year period, and an increase of 2.1% ... points of contribution from the LDR Holding Corporation acquisition, ... quarter of 2016, or 0.3% on a constant currency ...
(Date:7/26/2017)... 26, 2017 Sancilio Pharmaceuticals Company, Inc. (SPCI) ... trial evaluating Altemia TM , an oral therapy for ... Cell Disease (SCD). The SCOT Trial, is a double-blind, ... safety of Altemia TM in pediatric patients aged ... IND 125274. "The ...
Breaking Medicine Technology: