Navigation Links
Mitosis gets harder thanks to new gene discovery
Date:4/3/2008

A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery published today.

Scientists from the University of Bath have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

In research published in the journal Molecular Biology of the Cell, the scientists have shown that the protein is essential for building the microtubules that allow the two halves of the cell to slide apart.

What makes mitosis so interesting is that it is one of the biological processes that everyone remembers from their days at school, said Dr Andrew Chalmers from the Universitys Department of Biology & Biochemistry.

As well as being one of Natures most important processes, our interest in mitosis stems from the fact that if you want to kill cancer cells, then stopping them from dividing is a useful way of doing this.

Several cancer treatments block cell division by targeting microtubules, Taxol is a well known example. It is even possible that RASSF7 might be a future drug target.

During the different phases of mitosis the pairs of chromosomes within the cell condense and attach to microtubule fibres that pull the sister chromatids to opposite sides of the cell.

The cell then divides in cytokinesis, to produce two identical daughter cells.

RASSF7 is the latest of a battery of proteins involved in managing the complex process of mitosis.

During mitosis, the chromosomes containing the DNA are pulled apart in two halves by an array of microtubules centred on the centrosomes, said Dr Chalmers.

Without the RASSF7 protein, the microtubules do not develop properly and cell division is halted.

This is the first functional study of this protein, and we hope to extend our knowledge of how it works in the future.

The research was funded by the Medical Research Council.

The work was carried out in Dr Chalmers laboratory by Dr Victoria Sherwood and two final year undergraduate project students from the University, Ria Manbodh and Carol Sheppard.

Dr Sherwood will now continue her research on cancer at a new job at the Lund University Clinical Research Centre, Sweden.


'/>"/>

Contact: Andrew McLaughlin
press@bath.ac.uk
44-012-253-86883
University of Bath
Source:Eurekalert

Related medicine news :

1. Dementia in More Educated Hits Later But Harder
2. Vincent Corso and Daniel Trush Win 2007 Avis We Try Harder Awards
3. Studies Reveal Why Breast Cancer Hits Black Women Harder
4. Survey Says: Patients Prep Harder for Vacation than for an Operation
5. Digest This: Digestive Health Harder to Maintain Than Financial Health
6. Older Women Have Harder Time Preserving Muscle Than Men
7. Long Term Care Insurance Gains Momentum Thanks to State Promotions, a Leading Brokerage Reports
8. 600 Smiles Restored Thanks to the AACDCFs Give Back A Smile Program - October Marks National Domestic Violence Awareness Month
9. World Health Organization thanks CBM For their outstanding work
10. Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca
11. Its More Than the Turkey Dinner That Will Leave You Feeling Bloated This Thanksgiving
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize each ... Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into hand ... select a ProHand generator and drag it above media or text in the Final ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
(Date:6/24/2016)... 2016  Collagen Matrix, Inc., ("Collagen Matrix") the ... of collagen and mineral based medical devices for ... Bill Messer has joined the company as ... the growing portfolio of oral surgery, neurosurgery, orthopaedic ... joins the Collagen Matrix executive team as an ...
(Date:6/24/2016)... , June 24, 2016 ... has announced the addition of the " Global ... This report ... provides an updated review, including its applications in various ... total market, which includes three main industries: pharmaceutical and ...
Breaking Medicine Technology: