Navigation Links
Missing Gene Tied to Bone Marrow Transplant Problems
Date:11/22/2009

Variation can cause donated cells to attack recipient's tissue, study finds,,

SUNDAY, Nov. 22 (HealthDay News) -- Researchers are reporting that a genetic variation -- a missing gene -- boosts the risk that someone who's had a bone-marrow transplant will develop a complication called graft-versus-host disease.

The immune system-related complication occurs after surgery when the recipient has the variation and the donor does not.

When that's the case, the immune cells from the donor go on the attack against the recipient's tissues.

"This finding gives us a glimpse into the genetic incompatibilities that can complicate transplants," the study's lead author, Steven McCarroll, an assistant professor at Harvard Medical School and an associate member of the Broad Institute of MIT and Harvard, said in an institute news release. "There are likely many other compatibility loci left to be found, and with the enhanced capabilities for surveying human genetic variation, it will become increasingly feasible to find them."

As for developing a test to look for the genetic variation, McCarroll said it's not clear yet if that's necessary.

The findings appear in the Nov. 22 online edition of Nature Genetics.

More information

The U.S. National Library of Medicine has more on bone marrow transplants.



-- Randy Dotinga



SOURCE: Broad Institute of MIT and Harvard, news release, Nov. 22, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Scripps research scientists find missing puzzle piece of powerful DNA repair complex
2. Scientists decipher missing piece of first-responder DNA repair machine
3. Consumers Overlooking Opportunities at Open Enrollment May be Missing Out
4. Project Lifesaver International Receives Federal Assistance for the Missing Alzheimers Patient Assistance Program
5. Medicares Missing Link: Care Coordination and Family Caregiving, by Dan Tobin, M.D., CEO of Care Support of America
6. Connectyx Partners with InstantAmber, a Leader in Child Safety and Missing Children Awareness
7. Lilly Chairman & CEO Lechleiter Says Innovation Is Vital-But-Missing Plank in Health Reform Debate
8. Social Security Problems Are Misplaced Scare Tactics and Media Missing Story of Solvency, Says Former Congressional Aging Committee Chief of Staff Bob Weiner
9. Survey shows Americans may be missing direct route to head and neck cancer care
10. New Survey Shows School Kids 'Wagging' Breakfast Are Missing Healthy Brain Fuel
11. MedQuist Announces Entry of Final Judgment Approving Settlement and Dismissing Medical Transcriptionist Class Action
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Lafayette, California (PRWEB) , ... ... ... a pioneer in the patient payment industry today announced its strategic partnership ... and health system workflows. , The two companies’ proven, proprietary technology combine ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
Breaking Medicine Technology: