Navigation Links
Missing Follow-Up Colonoscopies Could Raise Colon Cancer Risk
Date:8/24/2012

By Carina Storrs
HealthDay Reporter

THURSDAY, Aug. 23 (HealthDay News) -- People at higher risk of developing colorectal cancer may be able to reduce their risk by getting thorough colonoscopies and adhering to recommendations for follow-up exams, a new study suggests.

Researchers in Germany looked at more than 400 people with polyps -- growths in the colon and rectum that can lead to cancer -- that had been detected in the past 10 years. About a third of them developed colorectal cancer.

The researchers found that those with colorectal cancer were more likely to have neglected getting a follow-up colonoscopy within five years of detection and to not have had their polyps completely removed upon detection.

These colonoscopy-related factors accounted for two in five cancer cases, whereas factors related to the polyps themselves, such as the number of polyps a patient had, were only associated with one in five cases, the researchers said.

The study was conducted by researchers at the German Cancer Research Center and the University of Heidelberg, and was published in the Aug. 21 issue of the journal Annals of Internal Medicine.

"This study found that incomplete removal of polyps at colonoscopy in patients with a history of precancerous polyps and lack of follow-up colonoscopy within five years were the most important factors linked to subsequent development of colorectal cancer," said Dr. Frank Sinicrope, a gastroenterologist and medical oncologist at the Mayo Clinic in Rochester, Minn. Sinicrope was not involved in the research.

"Not achieving these objectives can result in failure to realize the full potential of colonoscopy to prevent colorectal cancer," Sinicrope added.

The German study involved 155 participants who had been diagnosed with colorectal cancer and 260 participants who, although they had at least one polyp detected, did not have colorectal cancer. More than 60 percent of the participants were 70 years old or older. Two-thirds were men.

The group found that participants who developed cancer were almost four times as likely as those who did not to still have some of their polyps, and about three times as likely to have let at least five years go by without a follow-up colonoscopy.

In contrast, the only characteristic of polyps that was associated with cancer risk was having at least three detected, which was twice as likely in the group that developed colorectal cancer.

Larger polyps were not associated with greater colorectal cancer risk in this study, and that may be because they are easier for the doctor to remove, according to Dr. Jeffrey Meyerhardt, an oncologist at the Dana-Farber Cancer Institute in Boston.

The study also found that the association between colorectal cancer and waiting more than five years for a follow-up colonoscopy was particularly strong for participants who were under 70; this group was more than six times as likely to have cancer.

It also is critical for younger patients to adhere to follow-up recommendations, Sinicrope said.

Patients also should take an active role in ensuring they get good colonoscopies, Meyerhardt added.

"It's a reasonable question to ask the person doing your colonoscopy: 'Have you done a lot of these in the past?'" he said. "If [your doctor] only practices them very infrequently and does a scope once a month, that may be an issue."

After the procedure, "discuss with the doctor ... how good of a colonoscopy they did and if they were satisfied they could see everything," Meyerhardt said. "If [a polyp] was removed, what were the characteristics and when should follow-up be?"

A follow-up or surveillance colonoscopy is important even if polyps were completely cut out because "somebody who makes polyps has a tendency to make more polyps in the future," Meyerhardt explained.

The American Cancer Society advises that people who have one or two small precancerous polyps detected should have another colonoscopy within five to 10 years, while those who had more than two small polyps or at least one large polyp detected should get a follow-up test after about three years.

The American Cancer Society estimates that there will be about 140,000 new cases of colon and rectal cancer in 2012. Colorectal cancer is the second most common cause of cancer-related death in the United States.

More information

For more information about colorectal cancer and colonoscopies, visit the American Cancer Society.

SOURCES: Frank Sinicrope, M.D., gastroenterologist, medical oncologist, Mayo Clinic, Rochester, Minn.; Jeffrey Meyerhardt, M.D., M.P.H., oncologist, Dana-Farber Cancer Institute, associate professor, medicine, Harvard Medical School, Boston; August 21, 2012, Annals of Internal Medicine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mystery of the missing breast cancer genes
2. National poll: Low cost, lifesaving services missing from most older patients health care
3. Medical follow-up in celiac disease is less than optimal
4. 6 month follow-up of patients with benign MRI-guided breast biopsies may not be necessary
5. Study examines benefit of follow-up CT when abdominal ultrasound inconclusive
6. West Nile Outbreak Could Be Biggest Ever: CDC
7. Could Food Flavors Act Like Mood-Stabilizing Drugs?
8. DNA wires could help physicians diagnose disease
9. Red wine compound could help seniors walk away from mobility problems
10. Could FastStitch device be the future of suture?
11. Scientists decode TREX which could see new treatments for cancer realized
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Missing Follow-Up Colonoscopies Could Raise Colon Cancer Risk
(Date:3/24/2017)... ... March 24, 2017 , ... The iaedp Foundation, the premier ... professionals caring for those suffering from the full spectrum of disordered eating, announced today ... disorders professionals from nearly all 50 states and several countries converged on the Green ...
(Date:3/24/2017)... ... March 24, 2017 , ... Shamanic healer and teacher ... Healing and Spiritual Awakening, proudly presents her Sacred Peru retreat with world ... and spiritual journey during the Summer Solstice will also be her final international ...
(Date:3/24/2017)... PA (PRWEB) , ... March 24, 2017 , ... ... Oncology Nursing Society (ONS) wanted to create a communications platform that positions them ... this goal, Elliance and ONS reinvented their online publication as an always-on, always-fresh ...
(Date:3/24/2017)... ... March 24, 2017 , ... On June ... ERISA Benefit Claims Litigation seminar in Chicago, Illinois. She will present on: ... of cases litigated under ERISA involve claims for long-term disability benefits. This ...
(Date:3/24/2017)... ... March 24, 2017 , ... Viewers who like to educate themselves ... facts, cultural practices, goods, services, and societal issues tend to appreciate and love the ... popular practice of utilizing running events for causes around the world. , ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... DUBLIN , Mar 24, 2017 Research ... in Drug Discovery and Diagnostics, 2017 - 2035" report to ... The ... current landscape and future outlook of the growing market of deep ... data revolution, deep learning algorithms have emerged as a novel solution ...
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... Global Strategic Business Report" report to their offering. ... The report provides separate comprehensive analytics for ... Europe , Asia-Pacific , ... are provided for the period 2015 through 2022. Also, a six-year historic ...
(Date:3/24/2017)... , March 23, 2017  Mirabilis Medical, a ... medical technology for non-invasive surgery, announced today CE ... for treatment of uterine fibroids throughout the European ... received approval from the US Food and Drug ... Mirabilis System in the United States.  The Mirabilis ...
Breaking Medicine Technology: