Navigation Links
Missing Chromosome Improves Response to Brain Tumor Treatment
Date:2/19/2008

Findings show patients live average of 4 years longer than those without genetic abnormality

TUESDAY, Feb. 19 (HealthDay News) -- The lack of a chromosome actually helps people with a rare, aggressive brain tumor respond better to a new treatment, new findings show.

Gliomatosis cerebri is a type of inoperable brain tumor that is difficult to diagnosis and has an extremely variable prognosis. A study of 25 people with the condition showed that those missing chromosomes 1p and 19q did vastly better on the chemotherapy drug temozolomide, living an average of four years longer than those without the genetic abnormality.

The study is published in the Feb. 19 issue of Neurology.

"Temozolomide is now our first choice of treatment for patients with gliomatosis cerebri, especially when missing chromosomes 1p and 19q," Dr. Marc Sanson of INSERM, the French government health agency in Paris, said in a prepared statement.

Those in the study underwent genetic testing and received monthly treatments of temozolomide for up to two years. The drug had only recently been proposed as a new treatment for gliomatosis cerebri, Sanson said.

Eighty-eight percent of those missing the chromosomes responded well to the drug compared with only 25 percent of those with the chromosomes, Sanson said. Those without it also survived an average of 5.5 years compared with only 15 months for the group with the chromosomes intact. Those missing 1p and 19q also had more months without the tumor progressing, he added.

"Before now, we weren't sure which factors influenced how well a person with this type of brain tumor would respond to the treatment," Sanson said.

More information

The National Institute of Neurological Disorders and Stroke has more about brain tumors.



-- Kevin McKeever



SOURCE: American Academy of Neurology, news release, Feb. 18, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The National Center for Missing & Exploited Children, Wal-Mart, and Abbott Host Child Safety Events
2. Justice Department to Hold Media Event to Demonstrate New Database for Matching Unidentified Remains and Missing Persons Information
3. Some antipsychotic drugs may be missing their mark
4. The missing link between belly fat and heart disease?
5. Teens, Young Adults Missing Out on Latest Cancer Advances
6. Two Laptop Computers Missing From Lifebloods Main Office
7. Grant Supports Study of Abnormal Ring-Shaped Chromosomes
8. Optherion Licenses Worldwide Rights to Develop Age-Related Macular Degeneration Diagnostics Based on Chromosome 10 Genetic Variations
9. Herceptin helps women with multiple chromosomes containing HER2 gene, study finds
10. Chromosome Abnormalities Raise Risk for Autism
11. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Missing Chromosome Improves Response to Brain Tumor Treatment
(Date:2/8/2016)... ... , ... Steve Helwig & Associates Insurance & Financial, serving the families of ... up with Citizens Opposed to Domestic Abuse in support of its efforts to provide ... victimized by the fear of violence in their own homes, donations may now be ...
(Date:2/8/2016)... ... February 08, 2016 , ... Remember the old saying “rub some ... to Perry A~, author of “Calcium Bentonite Clay” the health benefits of integrating clay ... and detoxifying the body. , A former motivational speaker, Perry A~ has since dedicated ...
(Date:2/8/2016)... ... February 08, 2016 , ... The Association of Home ... and the Home Health and Hospice ICD-10 Transition Workgroup are working closely with ... guidance and clarifications, to address concerns over the use of 'A' as the ...
(Date:2/8/2016)... ... February 08, 2016 , ... According to research ... U.S. require dental technicians to be certified or obtain continuing education. To increase ... the “What’s In Your Mouth?” campaign to inform dentists and patients about the ...
(Date:2/6/2016)... ... February 06, 2016 , ... ... , MEDIA ADVISORY: 5000 PERIOPERATIVE NURSES EXPECTED AT AORN SURGICAL CONFERENCE & ... nurses in the world with an estimated 5000 perioperative nurses in attendance ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... NORRITON, Pa. , Feb. 8, 2016 /PRNewswire/ ... of November Research Group (NRG),s pharmacovigilance technology ... pharmacovigilance system-related consulting services and an Oracle Argus ... compliance services to Life Sciences companies. ... strengthens and expands HighPoint,s life sciences capabilities and ...
(Date:2/8/2016)... , Switzerland and PALO ALTO, Calif. , ... biological and chemical manufacturing, and Kodiak Sciences Inc., a ... treatment of retinal disease, announced today agreements for the ... Lonza will manufacture material at multiple sites, including Slough ... --> --> Retinal diseases, such ...
(Date:2/8/2016)... , Feb. 8, 2016  Avista Pharma Solutions ("Avista ... Setzer as Chief Financial Officer (CFO). Mr. Setzer is ... of experience in various roles within growing technology and ... served as the Executive Director of Finance at INC ... Raleigh, NC . Previously, Mr. Setzer served ...
Breaking Medicine Technology: