Navigation Links
Miriam Hospital researcher awarded $2.9 million NIH grant to study impact of maternal smoking
Date:10/29/2013

(PROVIDENCE, R.I.) Laura Stroud, Ph.D., a researcher with The Miriam Hospital's Centers for Behavioral and Preventive Medicine, was recently awarded a 5-year, $2,885,481 grant from the National Institutes of Drug Abuse, part of the National Institutes of Health (NIH), to further her work on the physiological impact of maternal smoking on fetal development and behavior.

Funded through the NIH's premiere Research Project Grant (R01) program, Stroud's research involves the use of ultrasound technology to identify real-time, fetal markers of risk among women who smoke during their pregnancies. Her goal is to determine whether maternal smoking will influence trajectories of fetal behavior, stress response, and brain structures over pregnancy, and if it could also predict infant neurobehavioral deficits, such as attention and self regulation deficits.

Despite the warnings and known health risks, approximately one in five expectant moms in the U.S. continues to smoke during pregnancy. Studies have consistently found that prenatal cigarette smoke exposure is associated with increased rates of behavior problems, irritability, attention-deficit and hyperactivity disorder, the risk of conduct disorder, adolescent onset of drug dependence and the risk for criminal arrest in offspring.

"Although there have been pervasive sanctions against smoking during pregnancy, 13 to 30 percent of infants are born exposed," said Stroud. "Given continued high exposure rates and links to costly offspring outcomes, new and innovative approaches are needed to identify and protect high-risk children and help pregnant smokers quit."

Stroud's research group previously demonstrated effects of maternal smoking on attention and self regulation deficits and hyperarousal in infants.

As a next step, the researchers will use fetal ultrasound assessments to observe fetal behavior, response to mild stress (using a vibratory sound stimulus), and 3D assessment of fetal brain structures, followed by two infant neurobehavior and stress hormone (cortisol) reactivity assessments. Participants will include pregnant smokers and a control group of pregnant non-smokers.

Stroud said the findings could shed light on the real-time impact of maternal smoking during pregnancy, identify new pre-birth markers of risk that could improve clinical care for pregnant smokers and other high-risk pregnancies, pinpoint new therapeutic targets to protect exposed fetuses, and lead to the development of new and focused intervention efforts for pregnant smokers.

The principal affiliation of Laura Stroud, Ph.D., is The Miriam Hospital (a member hospital of the Lifespan health system in Rhode Island) and direct financial and infrastructure support for this project was received through the Lifespan Office of Research Administration. Stroud is also an associate professor of psychiatry and human behavior at The Warren Alpert Medical School of Brown University.


'/>"/>

Contact: Nancy Jean
njean@lifespan.org
Lifespan
Source:Eurekalert

Related medicine news :

1. Miriam researcher helps develop global hepatitis C recommendations for injection-drug users
2. Miriam study reveals financial benefits of a plant-based, Mediterranean diet
3. Miriam researchers urge physicians to ask younger men about erectile dysfunction symptoms
4. Hospital-based Point of Care Diagnostics: Products, Players and Outlook to 2017
5. The Mount Sinai Hospital First in the World to Offer Patients New FDA Approved Device for Severely Calcified Arteries
6. A New Imaging Efficiency Dashboard from Health Data Intelligence Shines the Spotlight on the Quality and Efficient Use of Outpatient Medical Imaging Tests at US Hospitals
7. NewYork-Presbyterian/Morgan Stanley Children's Hospital Physician Offers Tips for a Safe and Sweet Halloween
8. Barnes-Jewish Hospital Offering New FDA-approved Non-surgical Procedure for Mitral Valve Repair
9. Multicenter Study Led by Texas Children's Hospital & Baylor College of Medicine Finds Prenatal Diagnosis & Birth Location May Significantly Improve Neonatal HLHS Survival
10. Florida Hospital Teams Up with The Tampa Bay Lightning to Raise Awareness About Breast Cancer & The Pink Army
11. IU, Regenstrief initiative aims to decrease hospitalization of nursing home residents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/24/2016)... , ... June 24, 2016 , ... A recent ... most people are unfamiliar with. The article goes on to state that individuals are ... many of these less common operations such as calf and cheek reduction. The Los ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
Breaking Medicine Technology: