Navigation Links
Miriam Hospital receives renewal of NIH grant for AIDS Clinical Trials Group

(PROVIDENCE, R.I.) A $2.4 million grant renewal will support The Miriam Hospital's continued efforts in research and new treatments for HIV and AIDS. The Miriam Hospital is the largest HIV/AIDS care provider in the state.

The ACTG is a global network of 60 research sites with its operations and laboratory center based at Brigham and Women's Hospital in Boston. The ACTG conducts clinical trials in HIV-infected adults to test novel therapeutic interventions focused on HIV-associated inflammation and resulting end-organ disease, tuberculosis, viral hepatitis and HIV cure.

Karen Tashima, M.D., the lead researcher at The Miriam, received the National Institutes of Health grant renewal. Tashima leads the ACTG's Providence site, which operates under the program's Harvard/Boston/Providence Clinical Trials Unit. She says, "We are thrilled with the results that have come from the ACTG Network. The Miriam Hospital has been part of the Network since 2000. Our work has allowed us to foster new investigations and treatments for treating HIV and AIDS."

Tashima says, "The ACTG is an important HIV clinical studies network that, for example, proved that mother to child transmission could be dramatically reduced by having the pregnant woman take the anti-HIV medication AZT. Results of other ACTG studies have changed how we treat HIV infection, and have resulted in Department of Health and Human Services HIV guideline changes leading to improvements nationally in the standard of care for HIV treatment."

Dr. Tashima was the lead investigator and study chair for the OPTIONS trial that was conducted at 64 sites across the continental U.S. and in Puerto Rico. The OPTIONS trial was a multi-site study that showed patients with drug-resistant HIV can safely achieve viral suppression the primary goal of HIV therapy without incorporating the traditional class of HIV medications into their treatment regimen. The ACTG trial showed for the first time that treatment-experienced patients can leave out this class of medication, known as nucleoside reverse transcriptase inhibitors (NRTI), as part of the regimen. Treatment-experienced patients already need to take three active medications in order to achieve viral suppression, so eliminating NRTI medications can lessen pill burden and side effects.

The Miriam Hospital is the largest care provider in Rhode Island, treating more than 1,500 patients with HIV who are under ongoing care. These patients have access to the latest treatments in HIV through our studies at The Immunology Center. Tashima says that she and other researchers in the ACTG look forward to more promising results coming from the research afforded by the grant renewal, which will allow The Miriam to continue to serve as an ACTG clinical research site for the 2014-2020 time period.


Contact: Elena Falcone-Relvas

Related medicine news :

1. Miriam Hospital study shows social gaming site effective weight loss tool
2. Miriam Hospital study links intimate partner violence and risk of HIV
3. Miriam Hospital researcher awarded $2.9 million NIH grant to study impact of maternal smoking
4. Miriam researcher helps develop global hepatitis C recommendations for injection-drug users
5. Miriam study reveals financial benefits of a plant-based, Mediterranean diet
6. Miriam researchers urge physicians to ask younger men about erectile dysfunction symptoms
7. Smartphone app reads blood oxygen levels to hospital standards, advances to global obstetrics tests
8. Hospital food safety measures reduce risk of contaminated hospital food
9. One in 5 US hospitals dont put hand sanitizer everywhere needed to prevent infections
10. Better nurse staffing and education reduces patient deaths in European hospitals
11. Stand-alone facility for organ retrieval is more efficient, less costly than hospital
Post Your Comments:
(Date:11/25/2015)... , ... November 25, 2015 , ... ... where preparing the perfect dish and pleasing the palates of attendees is of ... bringing a dish to a seasonal get-together, give these recipes a try this ...
(Date:11/25/2015)... NV (PRWEB) , ... November 25, 2015 , ... Dr. ... patients to learn more about hair loss treatment with the Capillus272™ Pro laser therapy ... effective solution for thicker and fuller hair, without the need for surgery, prescription pills, ...
(Date:11/25/2015)... ... , ... According to an article published November 10th by The ... as a breakthrough for performing hernia repairs. The article explains that the biggest advantage ... it can greatly reduce the pain that a patient might otherwise experience after a ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... for physicians and athletic programs, launches new Wimbledon Athletics Facebook page ... testing young athletes for unsuspected cardiac abnormalities. About 2,000 people under the age ...
(Date:11/25/2015)... ... 25, 2015 , ... SCOTTSDALE, AZ) - Today, Dr. ... both surgical and non-surgical treatments, announced the expansion of his private practice capabilities ... , Highly trained and nationally recognized for his natural approach, Dr. Todd ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Japanese therapeutic drug monitoring market, including emerging ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the Global Cell Surface Testing Market: ... report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/26/2015)... November 26, 2015 ... universitetssjukhus ser potential att använda SyMRI för ... för patienter med multipel skleros (MS) ... med SyntheticMR AB för att kunna använda ... sjukhuset. Med SyMRI kan man generera flera ...
Breaking Medicine Technology: