Navigation Links
Minocycline Enhances the Efficacy of Perispinal Enbrel in Traumatic Brain Injury Treatment as well as Stroke Treatment and Alzheimer’s Treatment
Date:3/8/2013

(PRWEB) March 08, 2013

This study, http://onlinelibrary.wiley.com/doi/10.1111/bph.12139/abstract soon to be published in the British Journal of Pharmacology and available now as an abstract online, delineates the mechanisms by which minocycline reduces inflammation. This peer-reviewed article critically reviews recent human and animal research demonstrating the potential for minocycline to provide neuroprotection and ameliorate the impairments experienced by those affected by traumatic brain injury (TBI), stroke and Alzheimer's disease. The authors elucidate how minocycline exerts neuroprotective and neuroregenerative effects in response to TBI, stroke and Alzheimer's. These processes are entirely different from those of etanercept. Perispinally administered etanercept inhibits the production of TNF-alpha in the brain. Minocycline also inhibits the production of TNF-alpha as well as a number of related cytokines. In 2012 Augusto Ramirez, M.D., began treating TBI, stroke and Alzheimer’s patients with perispinal Enbrel coupled with oral minocycline. The result has been improved outcomes. This article: Minocycline: Far beyond an Antibiotic provides broad scientific rationale for the inclusion of oral minocycline adjunctively with perispinally administered etanercept for the treatment of TBI, stroke and Alzheimer's disease.

Neurological Wellness Center began holding perispinal injection technique training courses in the spring of 2011. Since then physicians, nurses and lay caregivers have come from around the world to their Center in Managua, Nicaragua for individualized instructional courses teaching this procedure. Presently Neurological Wellness Center remains the only institution in the world teaching this perispinal Enbrel injection procedure. For more information about Neurological Wellness Center’s perispinal injection courses visit: http://reversealzheimersnow.com.

For many, flying to Managua, Nicaragua to receive this personalized training is an enormous expense and inconvenience. To overcome this problem, Neurological Wellness Center, under the direction of Augusto Ramirez, M.D., created Perispinal Enbrel Step-By-Step Instructional Video and accompanying e-book. This 24-minute video and 37-page e-book are now available online at http://www.neurological-recovery-guide.com.

Augusto Ramirez, M.D., Director of Neurological Wellness Center, a private medical group in Managua Nicaragua, authorized this press release.

Neuroinflammation contributes to a portion of the impairments people with Traumatic Brain Injury, stroke and Alzheimer’s disease experience. Last year a study published in the Journal CNS Drugs and available online: http://www.ncbi.nlm.nih.gov/pubmed/23100196, systematically examined the clinical responses of 629 patients afflicted by stroke or traumatic brain injury following the perispinal administration of Enbrel (Etanercept). The mean age of the stroke patients was 65.8 years. The mean interval between stroke and perispinal Enbrel treatment (PSE) was 42.0 months. The mean age of the traumatic brain injury (TBI) patients was 34.7 years. The mean interval between TBI and PSE treatment was 115 months.

Comprehensive pre-treatment and post-treatment assessments were made, with particular attention given to motor function, walking, pain, sensation, cognition and mood. A variety of standardized instruments were utilized in making these assessments. Neurological Wellness Center finds the results of this study to be extraordinarily noteworthy, not simply for the degree of the improvements observed but also for the extent of improvements across many areas of assessment. Equally striking was the rapidity of the improvement. Observations such as “rapid motor improvement beginning within minutes: was routinely observed in both post-stroke and the TBI patients” are ubiquitous throughout this observational study. The fact that the mean interval between stroke and PSE was 42.0 months and TBI and PSE 115 months makes these results even more remarkable. These results herald a new paradigm of understanding stroke and traumatic brain injury; whereby a self-perpetuating cascade of inflammation is produced in response to the trauma and the on-going inflammation contributes substantially to the impairments people experience. Once this inflammation is attenuated, significant recovery of physical and cognitive function becomes a reality these people experience often for the first time in years.

"The addition of minocycline to our treatment protocol has resulted in improved treatment outcomes." Augusto Ramirez M.D.

Dr. Steve Ralph, Associate Professor at Griffith University School of Medicine in Australia came to our Neurological Wellness Center in Managua and received instruction in perispinal Enbrel injection procedure. Dr. Ralph has stated; "These results represent a sea change in therapeutic possibilities for stroke and TBI patients. I have observed first hand rapid clinical improvement in patients. Rarely do we see such a radical breakthrough in medical treatment as this."

The TBI treatment, stroke treatment and Alzheimer’s treatment protocols Dr. Augusto Ramirez utilizes all involve combining perispinal Enbrel injections with oral minocycline. Additionally, he advises supplementing with N-acetylcysteine, fish oil and astaxanthin. To learn more about ameliorating the impairments caused by TBI, stroke and Alzheimer’s disease by reducing inflammation in the brain visit: http://www.neurological-recovery-guide.com. To schedule a personal hands-on training covering all aspects of perispinal Enbrel injection procedure visit: http://www.reversealzheimersnow.com. For the lowest Enbrel price in North American visit: http://www.genuine-enbrel-cheaper.com/

//clinicaltrials.gov/show/NCT01463384
Clinical Trial; Minocycline in patients with Alzheimer's disease.

//clinicaltrials.gov/show/NCT01463384
Clinical Trial; Minocycline treatment in acute stroke; An open label, evaluator-blinded study.

//clinicaltrials.gov/ct2/show/NCT01058395
Clinical Trial; Safety of minocycline in the treatment of traumatic brain injury (TBI)

//stroke.ahajournals.org/content/41/10/2283.short
Minocycline to improve neurologic outcome in stroke; a dose-finding study.

//.ncbi.nlm.nih.gov/pubmed/17406652
Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models.

//.fasebj.org/content/23/3/739
Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease.

//alzheimers.org.uk/site/scripts/documents_info.php?documentID=287
Analysis of the antibiotic minocycline as a treatment for dementia.

//journals.lww.com/neurosurgery/Abstract/2001/06000/Minocycline_Reduces_Traumatic_Brain.51.aspx
Minocycline reduces traumatic brain injury-mediated capase-1 activation , tissue damage and neurological dysfunction.

ncbi.nlm.nih.gov/pubmed/20796174
Therapeutic evaluation of etanercept in a model of traumatic brain injury.

ncbi.nlm.nih.gov/pubmed/21254790
Rapid improvement of chronic stroke deficits after perispinal etanercept: three consecutive cases.

ncbi.nlm.nih.gov/pubmed/11428551
Tumour necrosis factor-alpha is increased in the cerebrospinal fluid and serum of ischaemic stroke patients and correlates. with the volume of evolving brain infarct.

ncbi.nlm.nih.gov/pubmed/19027875
Perispinal etanercept for neuroinflammatory disorders.

ncbi.nlm.nih.gov/pubmed/19075734
Inflammatory cytokines in acute ischemic stroke.

neurologyindia.com/article.asp?issn=00283886;year=2012;volume=60;issue=1;spage=23;epage=28;aulast=Padma
Efficacy of minocycline in acute ischemic stroke: A single-blinded, placebo-controlled trial.

medpagetoday.com/Neurology/Strokes/6835
Minocycline Reduces Stroke Damage in Late-Presenting Patients.

neurology.org/content/69/14/1404.abstract
Minocycline treatment in acute stroke.

ncbi.nlm.nih.gov/pubmed/19091170
Inflammatory markers and stroke.

tobinick.com/videos/cognitive-and-neurological-improvement-after-the-inrs-patented-etanercept-treatment-four-years-after-stroke/
Cognitive and neurological improvement after the INR’s patented etanercept treatment four years after stroke.

strokebreakthrough.com/videos/rapid-improvement-8-years-after-stroke-with-the-patented-inr-local-etanercept-treatment/
Rapid improvement 8 years after stroke with the patented INR treatment.

sciencedirect.com/science/article/pii/S1090380108001808
Effects of Etanercept and Minocycline in a rat model of spinal cord injury.

ncbi.nlm.nih.gov/pmc/articles/PMC1785182/
TNF-alpha modulation for treatment of Alzheimer's disease, 6-month pilot study.

MedGenMed 2006, 8:25. PubMed Abstract, Demonstrates the efficacy of perispinal Enbrel as a treatment for Alzheimer's disease.

lef.org/magazine/mag2008/aug2008_Novel-Drug-Therapy-Immediately-Reverses-Alzheimers-Cognitive-Deficits_01.htm
Novel drug therapy immediately reverses Alzheimer's cognitive deficits.

sciencedaily.com/releases/2008/01/080109091102.htm
Reversal of Alzheimer's symptoms within minutes in human study.

ncbi.nlm.nih.gov/pubmed/20518613
Perispinal etanercept: a new therapeutic paradigm in neurology.

stevensponauglewordpress.com,
Enbrel injections reverse some Alzheimer’s disease symptoms.

Tobinick, E.L. and H. Gross, Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer’s disease. BMC Neurol, 2008. 8: p.27.

Tobinick, E.L. and H. Gross, Rapid cognitive improvement in Alzheimer’s disease following perispinal etanercept administration. J Neuroinflammation, 2008. 5: p.2.

Griffin, W.S., Perispinal etanercept: potential as an Alzheimer’s therapeutic. J Neuroinflammation, 2008. 5: p.3.

Tobinick, E., Perispinal etanercept for treatment of Alzheimer’s disease. Curr Alzheimer Res, 2007. 4(5): p.550-2.

McAlpine, F.E. and M.G. Tansey, Neuro-inflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s. J Inflammation Research, 2008. 1: p.29 39.

Read the full story at http://www.prweb.com/releases/2013/3/prweb10424735.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. A New Peer-Reviewed Study by CogniFit Finds That Brain Training Successfully Enhances Cognitive Ability, Whereas Physical Activity Does Not
2. Norah Guide Enhances Customer Support Satisfaction with New 24/7 Live Chat Support Specialists
3. The research is in: Physical activity enhances cognition
4. Lorna Kleidman Responds to New Findings that Exercise Enhances Memory
5. CycleBeads Natural Birth Control Method Ranks High in Perfect Use and Typical Use Efficacy According to Most Recent Review of Global Family Planning Reports
6. Study shows long-term efficacy of minimally invasive therapy for patients with Barretts esophagus
7. Muscular Development Store Comments on Efficacy of Protein Blends
8. Bioforce AG Announces Doctors Comments Showing Efficacy of Echinaforce for Immune Support Now On You Tube
9. Cancer screening: The efficacy of mammography screening
10. Confirmation of nitisinone efficacy for life-threatening liver disease
11. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... first interactive health literacy software tool, and the Cancer Patient Education Network (CPEN), ... patient education, today announce a new strategic alliance. , As CPEN’s strategic ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... ROCKVILLE, Md. , Sept. 22, 2017  As ... by Republican Senators Bill Cassidy (R-LA) and ... Kalorama Information notes that the medical device industry is ... the medical device tax, the 2.3% excise tax on ... Act.  But they also want covered patients, increased visits ...
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
(Date:9/13/2017)... has been named the official orthopedic and sports medicine ... 2018 College Football Playoff (CFP) National Championship to be played ... Atlanta, Georgia . OrthoAtlanta is proud to be ... many activities leading up to, and including the national championship ... OrthoAtlanta serves ...
Breaking Medicine Technology: