Navigation Links
Minimally invasive lymph node dissection in breast cancer has advantages over conventional surgery
Date:11/8/2012

Rochester, MN, November 9, 2012 Axillary lymph node dissection is done in conjunction with lumpectomy or mastectomy to determine if breast cancer has spread to the adjoining lymph nodes. The conventional surgical approach leaves a surgical scar that is unattractive and can restrict range of motion in the shoulder joint. Also, squeezing and pulling the tumor during the breast operation can stimulate tumor cell metastases. A new study in the December issue of Mayo Clinic Proceedings reports that an endoscopic technique, mastoscopic axillary lymph node dissection (MALND), can reduce these complications.

"Patients who undergo MALND experience improved operative outcomes, fewer complications, better functional conservation, and more attractive cosmetic results," says lead investigator Chengyu Luo, MD, of Fuxing Hospital, Capital Medical University, Beijing, China. "When performed by a well-trained surgeon, it is the treatment of choice."

1027 patients with operable breast cancer were randomly assigned to one of two study groups. The first group underwent a breast operation and axillary lymph node dissection by conventional surgical means (CALND). The second group first underwent MALND and then conventional breast surgery. Both groups were treated post-operatively with systemic therapy and radiation therapy. The patients were followed for 63 months.

The average blood loss in the MALND group was lower than that in the CALND group. There was no significant difference between the two groups with respect to operative time. The patients who underwent MALND had less axillary pain, numbness, paresthesias and arm swelling. The aesthetic appearance of the axilla was much better in the MALND group than in the CALND group.

No statistically significant difference in disease free survival or overall survival between the two groups was observed. However, there was a significant difference between the two groups in the distant metastasis rate in favor of the MALND group. "This is the most significant finding of the study," says Dr. Luo. "While there is not as yet any significant difference in survival, longer term follow-up (e.g., 10 years and 20 years) is still needed to make a definitive conclusion. This may suggest that the axillary operation should be done before the breast operation even in conventional surgery."


'/>"/>
Contact: Rachael Zaleski
mcpmedia@elsevier.com
215-239-3658
Elsevier Health Sciences
Source:Eurekalert

Related medicine news :

1. Obese appendectomy patients have fewer complications with minimally invasive operations
2. Minimally invasive surgery works well for abdominal aortic aneurysms, Mayo finds
3. Routine mammograms may result in significant overdiagnosis of invasive breast cancer
4. Invasive heart test being dramatically overused, Stanford study shows
5. Lower Risk for Bowel Obstruction With Less Invasive Surgery: Study
6. Less-Invasive Surgery for Esophageal Cancer Might Be Safer
7. Less Invasive Heart Valve Replacement Works for Elderly: Study
8. Accelerated chemotherapy given before surgery benefits patients with muscle-invasive bladder cancer
9. Patients Prefer More Invasive Form of Colon Scan: Study
10. EVINCI results could lead to 75 percent reduction of invasive procedures for patients with suspected CAD
11. Accelerated radiation treatment effective for noninvasive breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys ... peers for this recognition are considered among the top 2 percent of lawyers practicing ... members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
(Date:6/23/2016)... Calif. , June 23, 2016 ... CST on Thursday, July 7, 2016 , , , , ... ) , , , , EXPERT PANELISTS:  , , ... Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar ... The global pharmaceutical industry is witnessing an exceptional ...
(Date:6/23/2016)...  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... . ... ... ... Astellas ...
Breaking Medicine Technology: