Navigation Links
Minimally Invasive Heart-Valve Procedure Shows Promise: Study
Date:4/3/2011

By Amanda Gardner
HealthDay Reporter

SUNDAY, April 3 (HealthDay News) -- An experimental, minimally invasive procedure to place a new valve in a damaged heart is as good as conventional open-heart surgery, although it comes with a higher risk of stroke, researchers reported Sunday.

Transcatheter aortic valve implantation (TAVI) involves snaking a valve into position in the heart via an artery in the leg or directly through a tiny incision into the left ventricle of the heart, similar to a balloon angioplasty procedure to clear clogged arteries.

The collapsible heart valve, called the Edwards SAPIEN valve, is made by Edwards Lifesciences Corporation, which sponsored the study.

According to Dr. Paul Teirstein, an interventional cardiologist with Scripps Health in San Diego and a study author, the full procedure could cost up to $50,000 -- about the same as traditional aortic valve replacement surgery.

The device is not yet approved by the U.S. Food and Drug Administration, although the new study results will no doubt be taken into account when the agency makes its decision.

The new findings were presented at the annual meeting of the American College of Cardiology, in New Orleans.

Of the 200,000 people in the United States who need an aortic valve replacement, some 100,000 can't get one because their health is too frail to withstand traditional surgery, according to the study authors.

Previous results from the same study showed that TAVI actually bested standard medical therapy among patients who were too sick to undergo open-heart surgery. After one year, death rates went down 45 percent among those who underwent TAVI. Rates of patients needing to be hospitalized again also went down (22.3 percent in the TAVI group, versus 44.1 percent in the open-heart surgery group).

In this new trial, TAVI went head-to-head with traditional surgical valve replacement. Nearly 700 patients with aortic stenosis (when the aortic valve, which opens to allow the aorta to transport blood out of the heart and into the rest of the body, does not fully open) were randomly chosen for one of the two treatment groups.

After one year, 24 percent of the patients undergoing TAVI had died, compared to 27 percent in the surgery group. Eight percent and 4 percent had strokes, respectively. The median age of the patients was 84.

Another portion of the trial was also presented Sunday at the cardiology conference. This found that among 358 patients, TAVI was more cost-effective at the end of one year than traditional surgical therapy.

Findings presented at medical meeting should be viewed as preliminary because they typically do not undergo the same scrutiny as research published in peer-reviewed medical journals, scientists note.

"The buzz here is that this is a promising new approach," said Dr. Louis Teichholz, medical director of cardiac service at Hackensack University Medical Center in New Jersey. But it's not ready yet for widespread use, he added.

Teichholz pointed out a number of considerations, even beyond the stroke issue. Namely, this study involved very high-risk patients only.

"They had bad valves, a lot of symptoms, poor function in the heart," he said. "In the future, they [doctors] will be doing lower-risk patients so if this is going to have wide acceptance, it would have to be successful in less than the highest-risk patients."

The device is also quite large compared to second-generation devices already being developed in Europe, he said.

Another big question: When will the FDA actually approve the device. And the answer to that question, no one knows.

More information

The U.S. National Institutes of Health has more on traditional valve replacement surgery.

SOURCES: Louis Teichholz, M.D., medical director of cardiac service, chief of complementary medicine, Hackensack University Medical Center, New Jersey; April 3, 2011, presentation, American College of Cardiology annual meeting, New Orleans


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Minimally invasive surgeries: Laser suturing
2. Minimally invasive technique appears helpful to reanimate facial paralysis
3. 3-D Brain Navigation, Minimally Invasive Surgery Combine to Help Neurosurgeon Remove Tennis Ball-Sized Tumor
4. Singapore Embraces Minimally Invasive Spinal Surgery
5. Pancreatic cancer: Minimally invasive treatments and possible links to GI diseases
6. Cedars-Sinai study examines regional use of minimally invasive repair of aneurysms
7. Researchers quantify benefits of minimally invasive removal of hard-to-reach tumors
8. Study: Mechanomyography to be accurate in detecting nerves during minimally invasive spine surgery
9. Minimally invasive sports hernia repair may get athletes back in the game faster, study says
10. DCIS patients who get invasive breast cancer have higher mortality
11. Noninvasive Test May Identify Down Syndrome Early On
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... July 20, 2017 , ... LINET, an international leader in ... their product line: the AVE 2 birthing bed. , Perfectly suitable for labor, delivery, ... level of comfort and efficiency to every phase of childbirth. The AVE 2 has ...
(Date:7/20/2017)... ... July 19, 2017 , ... Dr. Jig Patel is pleased to ... with or without a referral. Understanding the difficulties that face people who are ... choose this permanent alternative to removable dentures and bridges. Not only does an implant ...
(Date:7/20/2017)... ... July 19, 2017 , ... Med Tech Solutions (MTS), ... based Health IT business unit of Constellation Inc., a move that will help the ... of operations in St. Louis, the acquisition is expected to help MTS ...
(Date:7/20/2017)... , ... July 19, 2017 , ... ... recently hiring senior healthcare project manager, Josh Christensen. As a leader in healthcare ... looks to further its healthcare resume in the Midwest with Josh now on ...
(Date:7/20/2017)... ... July 19, 2017 , ... A July 7th ... or worsen, varicose veins in some patients, according to medical experts. Washington State ... practices, like excessive sitting or standing, or regularly nicking yourself while shaving your ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)... July 12, 2017 CarpalAID is a revolutionary new product ... surgery. Carpal tunnel syndrome affects more than 8 million ... the rate of men. The common methods of treating CTS are ... uncomfortable hand braces or gloves. ... CarpalAID is a clear patch worn on ...
(Date:7/11/2017)... 11, 2017  The global market for liquid biopsy ... $394.1 million in 2016.  Although in early stages, the ... in particular as a result of the gradual shift ... recent introduction of a significant number of new liquid ... of tumor biomarkers to guide treatment decisions. ...
(Date:7/10/2017)... July 10, 2017  US medical equipment and supply ... according to Medical Equipment & Supplies: United ... Focus Reports. Continued increases in demand for medical services ... the population and supported by gains in disposable personal ... supplies. New product introductions will also drive sales as ...
Breaking Medicine Technology: