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Mimotopes Awarded a Major Peptide Library Supply Agreement by La Jolla Institute for their Studies Screening Dengue and Tuberculosis Pathogens
Date:12/21/2009

Mimotopes PepSets to be used by the La Jolla Institute to identify regions of the dengue virus and Mycobacterium tuberculosis that can be targeted by new vaccines

Melbourne, Australia (PRWEB) December 21, 2009 -- Mimotopes Pty Ltd, a subsidiary of Commonwealth Biotechnologies Inc. (NASDAQ Capital Market: CBTE), is pleased to announce that it has been awarded a major supply agreement for the synthesis of peptide libraries that will be used in screening dengue virus and Mycobacterium tuberculosis. The US government-funded screening projects, to be conducted at the La Jolla Institute for Allergy & Immunology (LIAI) require the synthesis of over 30,000 peptides on Mimotopes’ proprietary PepSetTM peptide library platform. With the use of this technology, the La Jolla Institute aims to identify regions of the dengue and Tuberculosis pathogens that can be targeted by new vaccines. The synthesis of the large targeted libraries in these projects builds on Mimotopes’ recent success in producing screening libraries for Hepatitis B Virus, Hepatitis C Virus, Human cytomegalovirus, HIV, influenza and the malaria parasite.

Understanding how the immune system recognises pathogens requires the testing of a large number of potential immune recognition sites, known as epitopes. Peptide libraries, such as those produced by Mimotopes, are ideal for this purpose because epitopes by their nature are short linear peptide sequences. According to Mimotopes’ CEO, Dr. Nick Ede, “Mimotopes has been synthesizing peptide libraries for immunology applications for over 20 years and has developed a unique proprietary solid-phase synthesis platform. Large screening projects requiring thousands of peptides, such as the epitope discovery programs at LIAI, are uniquely suited to Mimotopes’ peptide library platform because it allows for the production of higher purity peptides at lower unit cost
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