Navigation Links
Millions of people in Asia potentially exposed to health risks of popular herbal medicines
Date:3/18/2013

Scientists from King's College London are warning that millions of people may be exposed to risk of developing kidney failure and bladder cancer by taking herbal medicines that are widely available in Asia. The medicines, used for a wide range of conditions including slimming, asthma and arthritis, are derived from a botanical compound containing aristolochic acids. These products are now banned in the USA and many European countries but the herbs containing this toxic acid can still be bought in China and other countries in Asia and are also available worldwide over the internet.

The scientists reviewed worldwide cases of aristolochic acid nephropathy (AAN) a type of kidney failure caused by the intake of these acids. They explain the clinical basis for the disease and propose strategies to help doctors identify it and treat patients more effectively. They suggest that there may be many thousands of cases across Asia that are undiagnosed or misdiagnosed. With the outcome of their study, the researchers hope to raise awareness of the risks of aristolochic acids and reduce the global disease burden from this severe condition.

Lead author Professor Graham Lord, Director of the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Guy's and St Thomas' NHS Foundation Trust and King's College London, said: 'We have found evidence that many millions of people continue to be exposed to significant health risk due to these herbal medicines, widely used in China and India.' He added: 'There is also a striking lack of good quality evidence that might help guide the diagnosis and management of AAN.'

The paper, published in Annals of Internal Medicine, indicates that regulatory measures that have so far been adopted by national and international agencies may be inadequate in preventing harmful exposure to aristolochic acid. The compound is linked to many cases of kidney diseases and urothelial cancer, a form of cancer of which bladder cancer is the most known variant.

The authors reviewed the latest data on the epidemiology of AAN. They used several search engines to include all publications that are about or refer to aristolochic acid and Chinese herbal nephropathy and identified 42 different case studies and one trial relating to the management of the disease.

While explaining the origin and development of the disease, they propose a protocol which should make it easier to diagnose AAN. In addition, they suggest a new disease classification to help international clinicians better identify AAN patients, and draft guidelines for the treatment of these patients.

The research team consisted of an international collaboration of scientists from Belgium, Czech Republic, Germany and the UK. Dr Refik Gkmen, co-author from King's, said: 'This research is a great demonstration of how international scientific collaboration is vital in helping to describe how a toxin used in widely available products can lead to cancer.'


'/>"/>

Contact: Marianne Slegers
marianne.slegers@kcl.ac.uk
44-207-848-3840
King's College London
Source:Eurekalert

Related medicine news :

1. OHSU study: Misdiagnosis of MS is costing health system millions per year
2. Asthma Cases Continue to Rise in U.S., Affecting Millions
3. Millions of Americans Have Uncontrolled High Blood Pressure: CDC
4. Millions May Be Taking Vitamin D Unnecessarily, Analysis Suggests
5. Millions Prepare as Hurricane Sandy Starts Assault on East Coast
6. Millions Brace as Hurricane Sandy Slams the East Coast
7. Millions of patients still waiting for medical breakthroughs against neglected diseases
8. Millions of Nonsmokers Exposed to Smoke From Neighbors Apartments: Report
9. Author of the Uplifting Cancer Survival Guide, The C Card and Me, Gives Her Book Away to Millions
10. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
11. Norah Guides Millions in 2013 with More Choices in Customized Astrology Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... ... announced that student team BioCellection won the $30,000 Perlman Grand Prize of the 2016 ... the Gloeckner Undergraduate Award, the Michelson People’s Choice Award, and the Committee Award ...
(Date:4/29/2016)... Toronto, ON (PRWEB) , ... April 29, 2016 ... ... GlutenFreeCoupons.ca and the Canadian Celiac Association (CCA), is pleased to announce the launch ... about gluten-free products, nutritional articles, recipes, and more. The purpose of the ...
(Date:4/29/2016)... NY (PRWEB) , ... April 29, 2016 , ... New York City based oral and ... This surgery is a very effective way to treat obstructive sleep apnea. Dr. Jamali is ... Orthognathic surgery is a procedure that involves one or both jaw bones. This surgery is ...
(Date:4/29/2016)... ... April 29, 2016 , ... Jvion, ... round of funding led by Eastside Partners, with participation from existing investor Martin ... customer base and accelerate its technology and product roadmap. , “Jvion ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... enterprise focused entirely on patients with cancer, today announced that Lynne Malestic, RN, ... the 2016 CURE® Extraordinary Healer® for Oncology Nursing , which honors nurses ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)...   , ... le trimestre, soutenu par une croissance de +42% ... de +16% des ventes aux hôpitaux et cliniques  ... (Euronext : MKEA, FR0010609263 ; OTCQX : MKEAY), inventeur de Cellvizio®, ... chiffre d,affaires pour le premier trimestre clos au ...
(Date:4/27/2016)... , April 27, 2016   Zillion ... its digital health technology platform, which specializes in ... programs into scalable digital products, Zillion enables companies ... and empower consumers to take control of their ... live video conferencing – including one-to-one, group and ...
(Date:4/27/2016)... , April 27, 2016 ... addition of the  "Global Anesthesia Disposables Market ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) ,The global anesthesia ... a CAGR of 4.03% during the period ... a major threat to patients, safety. Organizations ...
Breaking Medicine Technology: