Navigation Links
Millions of people in Asia potentially exposed to health risks of popular herbal medicines
Date:3/18/2013

Scientists from King's College London are warning that millions of people may be exposed to risk of developing kidney failure and bladder cancer by taking herbal medicines that are widely available in Asia. The medicines, used for a wide range of conditions including slimming, asthma and arthritis, are derived from a botanical compound containing aristolochic acids. These products are now banned in the USA and many European countries but the herbs containing this toxic acid can still be bought in China and other countries in Asia and are also available worldwide over the internet.

The scientists reviewed worldwide cases of aristolochic acid nephropathy (AAN) a type of kidney failure caused by the intake of these acids. They explain the clinical basis for the disease and propose strategies to help doctors identify it and treat patients more effectively. They suggest that there may be many thousands of cases across Asia that are undiagnosed or misdiagnosed. With the outcome of their study, the researchers hope to raise awareness of the risks of aristolochic acids and reduce the global disease burden from this severe condition.

Lead author Professor Graham Lord, Director of the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Guy's and St Thomas' NHS Foundation Trust and King's College London, said: 'We have found evidence that many millions of people continue to be exposed to significant health risk due to these herbal medicines, widely used in China and India.' He added: 'There is also a striking lack of good quality evidence that might help guide the diagnosis and management of AAN.'

The paper, published in Annals of Internal Medicine, indicates that regulatory measures that have so far been adopted by national and international agencies may be inadequate in preventing harmful exposure to aristolochic acid. The compound is linked to many cases of kidney diseases and urothelial cancer, a form of cancer of which bladder cancer is the most known variant.

The authors reviewed the latest data on the epidemiology of AAN. They used several search engines to include all publications that are about or refer to aristolochic acid and Chinese herbal nephropathy and identified 42 different case studies and one trial relating to the management of the disease.

While explaining the origin and development of the disease, they propose a protocol which should make it easier to diagnose AAN. In addition, they suggest a new disease classification to help international clinicians better identify AAN patients, and draft guidelines for the treatment of these patients.

The research team consisted of an international collaboration of scientists from Belgium, Czech Republic, Germany and the UK. Dr Refik Gkmen, co-author from King's, said: 'This research is a great demonstration of how international scientific collaboration is vital in helping to describe how a toxin used in widely available products can lead to cancer.'


'/>"/>

Contact: Marianne Slegers
marianne.slegers@kcl.ac.uk
44-207-848-3840
King's College London
Source:Eurekalert

Related medicine news :

1. OHSU study: Misdiagnosis of MS is costing health system millions per year
2. Asthma Cases Continue to Rise in U.S., Affecting Millions
3. Millions of Americans Have Uncontrolled High Blood Pressure: CDC
4. Millions May Be Taking Vitamin D Unnecessarily, Analysis Suggests
5. Millions Prepare as Hurricane Sandy Starts Assault on East Coast
6. Millions Brace as Hurricane Sandy Slams the East Coast
7. Millions of patients still waiting for medical breakthroughs against neglected diseases
8. Millions of Nonsmokers Exposed to Smoke From Neighbors Apartments: Report
9. Author of the Uplifting Cancer Survival Guide, The C Card and Me, Gives Her Book Away to Millions
10. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
11. Norah Guides Millions in 2013 with More Choices in Customized Astrology Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... Delete® - Tattoo Removal and ... The Holiday Party Season. Save Up To 33% Off Botox® and Juvederm® Products Now ... the Phoenix Valley with Delightful Deals on Botox® and Juvederm® just in ...
(Date:12/7/2016)... ... , ... "ProBrand Flip allows FCPX editors to create unique logo reveals which ... Pixel Film Studios. , ProBrand Flip includes 30 flip book reveal animations. Easily reveal ... a variety of flip book animations. In Addition, users can modify each preset to ...
(Date:12/7/2016)... ... December 07, 2016 , ... “The Road To Restoration”: an informative ... a one hour a week showing of hands. “The Road To Restoration” is the ... you are familiar with the brass ring that you could reach out for, and ...
(Date:12/7/2016)... (Dec. 3, 2016) , ... (PRWEB) December 07, ... ... only patient advocacy nonprofit for individuals impacted by cerebral cavernous angiomas, was awarded ... New Mexico with a patient engagement program. New Mexico has more people with ...
(Date:12/7/2016)... ... December 07, 2016 , ... "Hacking into my medical record ... him as 'a genius.'" Thus begins "Margaret in Berlin," Book Twelve in the ... Wyston Books, Inc. These novels narrate the lives of a poor teenager ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... NESS ZIONA SCIENCE PARK , ... Israeli biotechnology company Kadimastem (TASE: KDST) announced today the signing of ... strategic collaboration between the companies. The synergy between the companies will ... Kadimastem-Corestem collaboration as a worldwide leader in innovative treatment for severe ... ...
(Date:12/7/2016)... -- Based on its recent analysis of the ... recognizes Nemaura Pharma Limited with the 2016 ... Technology Leadership. Nemaura Pharma,s transdermal drug delivery ... delivery technologies, especially in delivering biologics. Its ... Memspatch and Micropatch respectively, facilitate minimally painful ...
(Date:12/7/2016)... 2016 According to the latest ... Market Study on Multiplex Detection Immunoassay: North America to ... global multiplex detection immunoassay market is expected to witness a CAGR ... ...      (Logo: http://photos.prnewswire.com/prnh/20161114/438683LOGO) ...
Breaking Medicine Technology: