Navigation Links
Millennium Expands IBD Franchise with Addition of New Development Candidate
Date:3/17/2008

- Company advances oral antagonist of CCR9, a chemokine receptor believed

to play a critical role in Crohn's disease -

CAMBRIDGE, Mass., March 17 /PRNewswire-FirstCall/ -- Millennium Pharmaceuticals, Inc. (Nasdaq: MLNM) today announced the advancement of MLN3126, a new product candidate, from the Company's discovery engine to its development pipeline. MLN3126 is a selective antagonist of CCR9, a chemokine receptor known to be important in the migration of inflammatory cells into the gastrointestinal tract. Along with MLN0002, an antibody targeting the alpha4beta7 integrin, MLN3126 expands the Company's inflammatory bowel disease (IBD) franchise. MLN0002 already has demonstrated the ability to induce clinical remission in patients with ulcerative colitis and Crohn's disease and is expected to enter pivotal Phase III trials in late 2008 or early 2009 in both indications.

(Logo: http://www.newscom.com/cgi-bin/prnh/19991220/MLNMLOGO )

"The development of MLN3126 leverages our knowledge and experience in the area of IBD, a key focus area for Millennium," said Deborah Dunsire, M.D., Chief Executive Officer, Millennium. "Building on our scientific knowledge and broad patent estate in the area of chemokines, we have identified a product candidate that is differentiated from others in this field and potentially could benefit the millions of patients afflicted with Crohn's worldwide."

"We are delighted to move forward some very promising molecules in IBD. In addition to the positive direction of MLN3126, preliminary results from bridging studies with MLN0002 from our new commercially scalable cell line show favorable pharmaco
'/>"/>

SOURCE Millennium Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Eleventh Annual Lehman Brothers Global Healthcare Conference to Webcast Millennium Presentation
2. Cowen & Company 28th Annual Healthcare Conference to Webcast Millennium Presentation
3. 2008 Susquehanna Healthcare Conference to Webcast Millennium Presentation
4. BIO CEO & Investor 2008 Conference to Webcast Millennium Presentation
5. 2008 Merrill Lynch Global Pharmaceutical, Biotechnology and Medical Device Conference to Webcast Millennium Presentation
6. Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology
7. Millennium Enters Into $600,000 Product Development Agreement to Fund Product Development for the $20,000,000 Purchase Agreement with Provider Services, Inc.
8. Millennium to Webcast Business Update in Advance of 26th Annual JPMorgan Healthcare Conference
9. Millennium Submits sNDA for VELCADE(R) (Bortezomib) for Injection for the Treatment of Front-Line Multiple Myeloma
10. Millennium Pharmaceuticals Announces Webcast of American Society of Hematology Investor Event
11. Millennium Biotechnologies Inc. Signs Five Year $20,000,000 Purchase Agreement with Provider Services Inc. of Cleveland, Ohio
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... ... July 29, 2015 , ... According to the The ... legal, and are exposed to advertisements, for medicinal use are more likely to abuse ... where the use of marijuana is considered beneficial are more apt to use the ...
(Date:7/29/2015)... ... July 29, 2015 , ... The report “Atherosclerosis ... Atherosclerosis. Atherosclerosis is a slow, progressive disease that may start in childhood. The ... and best-in-class products. Complete report on Atherosclerosis Pipeline with 78 market data tables ...
(Date:7/29/2015)... ... July 29, 2015 , ... The NCCA re-accredited the Commission ... November 30, 2019, during its recent meeting. , The Commission received renewal of ... compliance with the NCCA’s Standards for the Accreditation of Certification Programs. NCCA ...
(Date:7/29/2015)... , ... July 29, 2015 , ... ... Michigan, changed its name in July to Kalamazoo Strength & Conditioning. , The ... , and “reflects the evolution of our training center over the past three ...
(Date:7/29/2015)... , ... July 29, 2015 , ... Today marks a ... which invests in women-led, growth companies and is led by a group of experienced ... responded positively, and voted with their dollars to be a part of the fund. ...
Breaking Medicine News(10 mins):Health News:New Study Reveals Teens Use Marijuana More in States Where Marijuana Is Legalized 2Health News:New Study Reveals Teens Use Marijuana More in States Where Marijuana Is Legalized 3Health News:Atherosclerosis Pipeline Assessment Review H1 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Atherosclerosis Pipeline Assessment Review H1 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Atherosclerosis Pipeline Assessment Review H1 2015 Market Research Report Available at RnRMarketResearch.com 4Health News:Commission for Case Manager Certification Receives Re-Accreditation of its CCM® credential from the National Commission for Certifying Agencies (NCCA) 2Health News:Commission for Case Manager Certification Receives Re-Accreditation of its CCM® credential from the National Commission for Certifying Agencies (NCCA) 3Health News:Kalamazoo’s CrossFit 269 Changes Name, Opens New Website 2Health News:Kalamazoo’s CrossFit 269 Changes Name, Opens New Website 3Health News:Kalamazoo’s CrossFit 269 Changes Name, Opens New Website 4Health News:Sofia Fund Surpasses Investor Goals 2
... may have isolated the substance most responsible// for the ... discovery that could revolututionise treatments for a host of ... Riyi Shi (REE-yee SHEE) has found that a chemical ... levels in spinal tissue for several days after a ...
... complete revascularization technique to increase blood flow to the ... to increase 5 years of patients’ life than the ... US, have found that patients who had blockages in ... they undergo arterial grafts that will restore blood flow ...
... always scared of going to the dentists, but did you know ... the way you feel scared about dental appointments? ,A new ... women are 2.5 times as likely to be afraid of dentists ... they’ll admit it less. ,In the first ever nation wide ...
... magnetic resonance imaging (MRI) technique called arterial spin ... ,Frontotemporal dementia is often mistaken for Alzheimer’s ... the latter in its behavior manifestations. The disease ... patterns characterized by repetitive or compulsive behavior, lack ...
... of Internal Medicine high intake of calcium// and vitamin D ... have shown that blood calcium and vitamin D levels are ... reproductive age of a women, is a characterized by ... significant number of women for up to two weeks prior ...
... with the help of anti fungal medication itraconazole can ... Manchester have broken new grounds in asthma treatment by ... bronchopulmonary aspergillosis, which is a form of asthma. , ... treated with steroids or drugs that have equally disastrous ...
Cached Medicine News:Health News:Acrolein may be the key to halting spinal cord damage 2Health News:Acrolein may be the key to halting spinal cord damage 3Health News:Acrolein may be the key to halting spinal cord damage 4
(Date:7/29/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/zcrjfz/global ... "Global Neurostimulation Devices Market 2015" report to ... global neurostimulation devices market to grow at a ... The report, Global Neurostimulation Devices Market 2015-2019, ... analysis with inputs from industry experts. The report ...
(Date:7/29/2015)... , July 29, 2015 At ... Expo, researchers will present findings that a first-of-its-kind ... with high accuracy, which could reduce the prevalence ... chlamydia screening easier and cheaper. Most ... because the infection often causes no symptoms, but ...
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/-- LabStyle Innovations Corp. (DRIO), today ... a national broadcast news segment in Australia ... following regulatory and reimbursement approval in that country. ... 1.2 million Australians living with diabetes. As a case in ... great solution for a 13 year old boy with Type ...
Breaking Medicine Technology:Global Neurostimulation Devices Market 2015-2019 2First Smartphone DNA Test for Chlamydia to Be Presented at 2015 AACC Annual Meeting 2First Smartphone DNA Test for Chlamydia to Be Presented at 2015 AACC Annual Meeting 3LabStyle Innovations' Dario Diabetes Management Solution Featured on 9 News Australia 2LabStyle Innovations' Dario Diabetes Management Solution Featured on 9 News Australia 3
... Jan. 10, 2012  BryanLGH Medical Center in Lincoln, ... Pharmacy Xpert clinical surveillance and intervention solution from ... therapy and improve pharmacist efficiency across BryanLGH,s facilities. ... "We selected Pharmacy Xpert because our pharmacists need ...
... DIEGO, Jan. 10, 2012  Receptos Inc. today ... transfer milestone under its license and technology ... Ortho-McNeil Janssen Pharmaceuticals, Inc.), for Receptos, breakthrough ... The relationship between Janssen Pharmaceuticals and Receptos, ...
Cached Medicine Technology:BryanLGH Medical Center Implements Pharmacy Xpert from Thomson Reuters to Enhance Medication Management 2BryanLGH Medical Center Implements Pharmacy Xpert from Thomson Reuters to Enhance Medication Management 3Receptos Achieves Milestone Under License of G-Protein Coupled Receptor Crystal Structure Determination Technology 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: