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Milestone Scientific Names Robert Presutti New Vice President of Sales and Marketing
Date:9/13/2007

COO Thomas Ronca Leaves to Pursue Other Career Opportunities

LIVINGSTON, N.J., Sept. 13 /PRNewswire-FirstCall/ -- Milestone Scientific, Inc. (OTC Bulletin Board: MLSS), the recognized leader in advanced injection technologies, today announced the appointment of Robert (Bob) A. Presutti as the Company's new Vice President of Sales and Marketing. Presutti is charged with the overall coordination, functional management and leadership of all sales, marketing and customer service activities of the Company. Milestone further reported that Thomas Ronca will be leaving his post as Company COO and President, effective September 12, 2007, so that he may pursue other career opportunities.

Leonard Osser, Chairman and CEO of Milestone, stated, "With a significant acceleration of the STA(TM) System market introduction planned, it is essential that we have capable and talented sales management in place to lead this and other planned product marketing initiatives. In this regard, we are delighted to welcome Bob to our senior leadership team and have great confidence that he will have an immediate and positive impact on our efforts to drive rapid worldwide market adoption of our advanced injection technologies."

Continuing, Osser commented, "On behalf of everyone at Milestone, I'd also like to thank Tom Ronca for his service to Milestone over the past two years and wish him nothing but success in his future endeavors."

Presutti brings Milestone nearly 20 years of professional sales and marketing experience, primarily within the medical and dental industries, with emphasis on new product introductions. As Director of Professional Sales at Optiva/Philips Healthcare, Inc., he helped to establish Sonicare as the #1 most recommended and dispensed electric toothbrush among dental professionals, and drove product sales from $5 million to over $28 million in a five year period. Immediately prior to joining Milestone, Presutti served as Director of Professional Sales at Grinrx Corporation, a start-up dental company in Washington. In May of 2005, he was recruited by the CEO of Brite Smile, Inc. to serve as Executive Vice President of Sales. In this role, he led the rebuilding of the dental product company's sales organization and relaunched its in-office whitening procedure in the professional dental channel. While at Thermoscan, Inc. and Medtronic, Nortech Division, Presutti held various sales management and market development positions of increasing responsibility. Presutti holds a BA degree in Business Administration from Monmouth University.

About Milestone Scientific, Inc.

Headquartered in Livingston, New Jersey, Milestone Scientific is engaged in pioneering proprietary, highly innovative technological solutions for the medical and dental markets. Central to the Company's IP platform and product development strategy is its patented CompuFlo(TM) technology for the improved and painless delivery of local anesthetic. Specifically, CompuFlo is a computer-controlled, pressure sensitive infusion, perfusion, suffusion and aspiration technology, which provides real-time readouts of pressures, fluid densities and flow rates, enabling the advanced delivery and removal of a wide array of fluids. The STA(TM) System, a computer-controlled local anesthesia delivery system which uses this technology provides dentists with audible and visual signals as to in-tissue pressure. Milestone's existing painless injection systems are currently sold in 25 countries. For more information on these and other innovative Milestone products, please visit the Company's web site found at http://www.milesci.com.

Safe Harbor Statement

This press release contains forward-looking statements regarding the timing and financial impact of the Milestone's ability to implement its business plan, expected revenues and future success. These statements involve a number of risks and uncertainties and are based on assumptions involving judgments with respect to future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond Milestone's control. Some of the important factors that could cause actual results to differ materially from those indicated by the forward-looking statements are general economic conditions, failure to achieve expected revenue growth, changes in our operating expenses, adverse patent rulings, FDA or legal developments, competitive pressures, changes in customer and market requirements and standards, and the risk factors detailed from time to time in Milestone's periodic filings with the Securities and Exchange Commission, including without limitation, Milestone's Annual Report on Form 10-KSB for the year ended December 31, 2006. The forward looking-statements in this press release are based upon management's reasonable belief as of the date hereof. Milestone undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

FOR MORE INFORMATION, PLEASE CONTACT:

Elite Financial Communications Group, LLC

Dodi Handy, President and CEO, or Daniel Conway, Chief Strategist

407-585-1080 or via email at mlss@efcg.net


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SOURCE Milestone Scientific, Inc.
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