Navigation Links
Mild traumatic brain injury may contribute to brain network dysfunction
Date:5/11/2012

RICHMOND, Va. (May 10, 2012) Even mild head injuries can cause significant abnormalities in brain function that last for several days, which may explain the neurological symptoms experienced by some individuals who have experienced a head injury associated with sports, accidents or combat, according to a study by Virginia Commonwealth University School of Medicine researchers.

These findings, published in the May issue of the Journal of Neuroscience, advance research in the field of traumatic brain injury (TBI), enabling researchers to better understand what brain structural or functional changes underlie posttraumatic disorders a question that until now has remained unclear.

Previous research has shown that even a mild case of TBI can result in long-lasting neurological issues that include slowing of cognitive processes, confusion, chronic headache, posttraumatic stress disorder and depression.

The VCU team, led by Kimberle M. Jacobs, Ph.D. , associate professor in the Department of Anatomy and Neurobiology , demonstrated for the first time, using sophisticated bioimaging and electrophysiological approaches, that mild injury can cause structural disruption of axons in the brain while also changing the way the neurons fire in areas where they have not been structurally altered. Axons are nerve fibers in the brain responsible for conducting electrical impulses. The team used models of mild traumatic brain injury and followed morphologically identified neurons in live cortical slices.

"These findings should help move the field forward by providing a unique bioimaging and electrophysiological approach to assess the evolving changes evoked by mild TBI and their potential therapeutic modulation," said co-investigator, John T. Povlishock, Ph.D. , professor and chair of the VCU School of Medicine's Department of Anatomy and Neurobiology and director of the Commonwealth Center for the Study of Brain Injury.

According to Povlishock, additional benefit may also derive from the use of this model system with repetitive injuries to determine if repeated insults exacerbate the observed abnormalities.


'/>"/>
Contact: Sathya Achia Abraham
sbachia@vcu.edu
804-827-0890
Virginia Commonwealth University
Source:Eurekalert

Related medicine news :

1. Scott & White Memorial Hospital uses device to revolutionize treatment of traumatic aortic injury
2. Traumatic Amputations in Children Have High Costs
3. Research team documents benefits of endovascular stent repair for traumatic aortic injury
4. Survivors of childhood cancers 4 times more likely to develop post-traumatic stress disorder
5. UCLA researchers, US military collaborate to open center for traumatic brain injury
6. Researchers urge reclassification of traumatic brain injury as chronic disease
7. National study finds 70 percent increase in basketball-related traumatic brain injuries
8. Researchers at SUNY Downstate find drug combination may treat traumatic brain injury
9. After traumatic event, early intervention reduces odds of PTSD in children by 73 percent
10. U of M researchers identify possible key to treating, understanding post-traumatic stress disorder
11. Researchers identify PTSD measures for use in traumatic brain injury research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... 2017 , ... Source Vitál Apothecary, a skin and body care company dedicated ... company had a successful visit to the 2017 ECRM Diet, Vitamin & Sports Nutrition ... in the nutritional, sports and health industries a chance to meet in private sessions ...
(Date:1/20/2017)... ... January 20, 2017 , ... Lice Troopers, the lice removal company ... with school-aged children since the holiday season. , “It happens every year around ... sharing hugs and taking photos, which is the head-to-head gateway that lice need to ...
(Date:1/20/2017)... ... 2017 , ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation ... trial has been life-saving as she has been on the trial for more ... diagnosed with ovarian cancer in 2009. She underwent standard chemotherapy but a year later ...
(Date:1/20/2017)... ... ... Magdalene: Grace is Greater than Sin”: a unique and memorable piece of literature ... Grace is Greater than Sin” is the creation of published author, Brenda Roberts, a ... had little knowledge of the female characters portrayed in the Holy Bible. , ...
(Date:1/20/2017)... ... ... examination of how God handles sin, including how to let go of lingering guilt and ... ten long years has been waiting to release this powerful insight about forgiveness that the ... the Lord for over twenty years, and he has been preaching and teaching the Word ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... ARMO BioSciences, Inc., a late-stage immuno-oncology company, ... lead investigational immuno-oncology drug AM0010 (PEGylated Interleukin-10) at the ... of Clinical Oncology (ASCO), taking place January 19-21, 2017 ... "AM0010 induces the expansion of novel T ... in the blood and tumors of our patients," said ...
(Date:1/20/2017)... , Jan 20, 2017 Research ... Testing Market By Type ([CBC, HGB/HCT, BMP, BUN Creatinine, Electrolyte Testing, ... By End-use, And Segment Forecasts, 2013 - 2024" report to ... ... 198.5 billion by 2024 Introduction of innovative solutions on ...
(Date:1/20/2017)... DUBLIN , Jan 20, 2017 ... Pharmaceutical Stability Testing Market Trends, Opportunities, and Future" report to ... ... market sizing, emerging trends, and technologies, and provides a snapshot of ... year is 2015 and forecasts are provided from 2016 to 2020. ...
Breaking Medicine Technology: