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MiddleBrook Pharmaceuticals Reports Second Quarter 2008 Results
Date:8/14/2008

rketable securities, compared to $18.0 million at March 31, 2008 and $2.0 million as of year-end 2007.

FINANCIAL GUIDANCE

Total revenue guidance for 2008 is unchanged from prior forecasts and is expected to be approximately $10 million to $12 million, resulting from Keflex product sales and assuming no generic competition to Keflex 750 mg capsules occurs during the year. MiddleBrook intends to issue additional financial guidance for 2008 following the completion of its anticipated financing transaction with EGI.

ABOUT MIDDLEBROOK PHARMACEUTICALS:

MiddleBrook Pharmaceuticals, Inc. (Nasdaq: MBRK) is a pharmaceutical company focused on the development and commercialization of anti-infective drug products that fulfill substantial unmet medical needs in the treatment of infectious disease. The Company is developing anti-infective drugs based on its novel biological finding that bacteria exposed to antibiotics in "pulses" are killed more efficiently and effectively than those under standard treatment regimens. Based on this finding, MiddleBrook has developed a proprietary, once-a-day pulsatile delivery technology called PULSYS(R). The Company currently markets the Keflex(R) brand of cephalexin and has received regulatory approval for MOXATAG(TM) -- the first and only once-daily amoxicillin product approved for marketing in the U.S. For more on MiddleBrook, please visit http://www.middlebrookpharma.com.

About MOXATAG:

MOXATAG(TM) (amoxicillin extended-release) Tablets are a once-a-day extended-release formulation of amoxicillin for oral administration consisting of three components: one immediate-release and two delayed-release. The three components a
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SOURCE MiddleBrook Pharmaceuticals, Inc.
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