Navigation Links
Middle-Aged Diabetics May Need Earlier Colon Checks

By Kathleen Doheny
HealthDay Reporter

TUESDAY, May 22 (HealthDay News) -- Researchers who say they've linked type 2 diabetes with earlier development of precancerous colon lesions recommend people with the blood sugar disorder start colorectal screenings at a younger age than others.

"Based on our data, it implies that people with diabetes should get screenings earlier, possibly at age 40, rather than at age 50," said Dr. Hongha Vu, a clinical gastroenterology fellow at Washington University in St. Louis.

However, another expert said more research is needed before making that recommendation. Also, the researchers cautioned that they can't say for sure that diabetes by itself raises the risk of the precancerous lesions and further study is required.

Experts know that diabetes is linked with an increased risk of colon and other cancers. Vu's team set out to determine if people with diabetes develop precancerous lesions, also called polyps or adenomas, earlier than people without diabetes.

The researchers compared the incidence of polyps in three groups of patients: those 40 to 49 with and without diabetes and those 50 to 59 without diabetes. Each group had 125 people.

All had colonoscopies between June 2005 and June 2011. In a colonoscopy, a doctor examines the large intestine with a long, thin tube that has a camera at the end. Any polyps found are removed so they can't progress to cancer.

The younger men and women with diabetes had a rate of polyps similar to the older people without diabetes, she found.

"We found that between the three groups, the adenoma detection rate in those 40 to 49 without diabetes was 14.4 percent, whereas it was significantly higher in those with diabetes in the same age range -- at 30.4 percent," she said. "This is a similar rate as those 50 to 59 without diabetes." The 50- to 59-year-olds had a rate of 32 percent, she found.

Vu took into account other risk factors, such as race, obesity and smoking, and still found that those in their 40s with diabetes had a higher rate of polyps.

She is scheduled to present her findings Tuesday at Digestive Disease Week in San Diego.

More than 25 million people in the United States have diabetes, according to the U.S. Centers for Disease Control and Prevention. Most have type 2 diabetes, in which the body doesn't properly use and produce insulin, a hormone needed to convert food into energy. Because diabetes cases are expected to soar in coming decades, partly driven by the obesity epidemic, the researchers believe the findings have important public health implications.

Without insurance, a colonoscopy costs about $1,200 or more.

Dr. John Petrini, past president of the American Society of Gastrointestinal Endoscopy, said the results are intriguing but need to be confirmed in larger studies.

"Is there something about that small group?" he asked. Only future studies can answer that, said Petrini, also a gastroenterologist at Sansum Clinic, Santa Barbara, Calif.

The American Diabetes Association declined to comment on the study. Currently, its standards of care states that diabetes (possibly only type 2) is linked with a higher risk of colorectal and other cancers. It advises those with diabetes to undergo "recommended age- and sex-appropriate cancer screenings and to reduce their modifiable cancer risk factors [obesity, smoking, physical inactivity]."

In 2008, the American College of Gastroenterology updated its guidelines for colorectal cancer screening, which now say current evidence supports a doctor's recommendation to screen earlier than age 50, perhaps age 45, for patients who have "an extreme smoking history or obesity." Many patients with diabetes are also obese.

Digestive Disease Week is sponsored by four societies: American Association for the Study of Liver Diseases; American Gastroenterological Association Institute; American Society for Gastrointestinal Endoscopy, and Society for Surgery of the Alimentary Tract.

Because this research was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

To learn more about colonoscopy, visit the American Gastroenterological Association.

SOURCES: Hongha T. Vu, M.D., gastroenterology fellow, Washington University, St. Louis; John Petrini, M.D., gastroenterologist, Sansum Clinic, Santa Barbara, Ca., and past president, American Society of Gastrointestinal Endoscopy; presentation, Digestive Disease Week, May 22, 2012, San Diego, Calif.

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
2. Knee pain common complaint in middle-aged and mature women
3. Elderly emergency patients less likely to receive pain medication than middle-aged patients
4. Restless legs syndrome may raise high blood pressure risk in middle-aged women
5. Research reveals that 10 percent of middle-aged Europeans are on antidepressants
6. Simple fitness test could predict long-term risk for heart attack, stroke in middle-aged people
7. Adverse changes in sleep duration are associated with lower cognitive scores in middle-aged adults
8. Hearing Loss Common Among Middle-Aged Adults: Study
9. Obese children have signs of heart disease typically seen in middle-aged adults
10. Middle-aged men: Could dwindling testosterone levels decrease sleep?
11. Middle-aged Americans report more mobility-related disabilities
Post Your Comments:
Related Image:
Middle-Aged Diabetics May Need Earlier Colon Checks
(Date:11/25/2015)... ... November 25, 2015 , ... ... sauna parts and accessories. , Sauna accessories help improve the bather experience in ... personality. From basic styles for the purist looking for simplicity in design to ...
(Date:11/25/2015)... LA (PRWEB) , ... November 25, 2015 , ... On ... the United States District Court of Connecticut on behalf of a home health care ... of all current or former home health care workers employed by Humana, Inc., Humana ...
(Date:11/25/2015)... Jacksonville, FL (PRWEB) , ... November 25, 2015 ... ... treatment center, is encouraging people across the country to celebrate their sobriety and ... invites people to post “before and after” photos this Thanksgiving with the hashtag ...
(Date:11/25/2015)... Boca Raton, Florida (PRWEB) , ... November 25, ... ... on-site diagnostic testing for physicians and athletic programs, launches new Wimbledon Athletics ... the importance of testing young athletes for unsuspected cardiac abnormalities. About 2,000 people ...
(Date:11/25/2015)... ... November 25, 2015 , ... Smiles by Stevens ... Bruxism, and moderate facial wrinkling. While many patients are aware of the benefits of ... success Botox® delivers to those suffering with discomfort, soreness, and pain as a result ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)...  The total global healthcare industry is expected to grow ... Latin America has the highest projected growth at ... Japan ), is second with growth projected at 11.5%. ... healthcare expenditure. In 2013-2014, total government funded healthcare was nearly ... to 41.2% in 2013-2014. In real terms, out of pocket ...
(Date:11/25/2015)... , Nov. 25, 2015 AAIPharma Services ... investment of at least $15.8  Million to expand ... Wilmington, NC . The expansion will provide ... meet the growing demands of the pharmaceutical and ... site expansion will provide up to 40,000 square ...
(Date:11/25/2015)... Israel , November 25, 2015 ... KTOV ) (TASE: KTOV), a biopharmaceutical company focused ... treatment of various clinical conditions, today announced the closing ... American Depository Shares ( ADSs ), each representing 20 ... up to 3,158,900 ADSs. The ADSs and warrants were ...
Breaking Medicine Technology: