Navigation Links
Micromet and MedImmune to Present New Clinical Data for Anti-CD19 BiTE(R) Antibody at American Society of Hematology Annual Meeting Showing Objective Clinical Responses in Relapsed Non-Hodgkin's Lymphoma Patients
Date:11/29/2007

BETHESDA and GAITHERSBURG, Md., Nov. 29 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI) and MedImmune, Inc. today announced that new data from an ongoing Phase 1 clinical trial of MT103 in patients with late- stage non-Hodgkin's lymphoma (NHL) will be presented at the 2007 Annual Meeting of the American Society of Hematology (ASH) on December 9 in Atlanta, Georgia. MT103, also known as MEDI-538, is a recombinant T-cell engaging antibody, or BiTE(R) antibody, targeting the CD19 antigen, which is uniquely expressed on B-cells. As the first BiTE antibody studied in humans, MT103 is currently being evaluated in Phase 1 and 2 clinical trials for the treatment of patients with various B-cell malignancies.

New data from the ongoing Phase 1 dose-escalating trial show evidence of objective complete and partial responses in relapsed follicular lymphoma (FL), mantle cell lymphoma (MCL), and chronic lymphocytic leukemia (CLL) patients. At the time of the analysis, dose levels tested ranged from 0.0005 to 0.030 mg/m2 per day, respectively. Among the 15 evaluable patients at dose levels of 0.015 and 0.030 mg/m2 per day, two complete responses, two partial responses, and two minimal responses were observed. One of the complete responses was in a patient with MCL. In addition, six patients experienced stable disease and three patients progressed during treatment. The full data set, which will include additional patients at a higher dose level than reported in the abstract, will be presented at ASH.

Six patients at dose levels 0.015 and 0.030 mg/m2 per day had tumor infiltration in the bone marrow, a location from which relapses of these diseases potentially emanate. The bone marrow infiltration in five out of si
'/>"/>

SOURCE Micromet, Inc
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Micromet Receives Regulatory Approval to Conduct a Phase 2 Clinical Trial Investigating MT103 (MEDI-538) in Patients with Acute Lymphoblastic Leukemia
2. Micromets BiTE(R) Antibodies Reveal Unique Mode of Action
3. MedImmune Resolves FDA Observations Regarding Manufacturing Process for FluMist(R)
4. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
5. Medimmune announces phase 2 safety data for anti-RSV antibody and national RSV surveillance results
6. MedImmune to present RSV surveillance and cost-effectiveness data at American Academy of Pediatrics
7. MedImmune presents new pharmaco-economic data at AAP regarding infants at high risk for RSV
8. AtriCure to Present at Thomas Weisel Partners 2007 Healthcare Conference
9. Matrixx Initiatives, Inc. to Present at the Roth Capital Partners 2007 New York Conference
10. BD to Present at the Bear Stearns 20th Annual Healthcare Conference
11. ATS Medical to Present at the 2007 Thomas Weisel Partners Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... is a seasoned and trusted leader who consistently delivers trendy ... have it lead the wedding dress industry into the future. ... for the global market. , “The CEO of VogueQueen is ... on continuing the goal of operational excellence and giving back ...
(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company offering ... follow it on Facebook, Twitter, and Pinterest. The fans will ... draws a lottery every week. , Moreover, the company has ... Click Angelweddingdress homepage for more information. , ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 AngelWeddingDress, the ... of 2015 maternity wedding dresses. View website ... are looking for maternity wedding dresses online for a ... gowns with high quality for them. Its maternity wedding ...
(Date:1/22/2015)... 2015 Juvent Sports ( http://www.juventsports.com ) ... PGA Merchandise Show to bestow a Juvent Sports Achievement ... golfer, Arlene McKitrick. The award commemorated and congratulated McKitrick ... win. She won her first amateur tournament in 1979 ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 ... after Fresenius Medical Care recalled its GranuFlo and NaturaLyte ... multidistrict litigation underway in U.S. District Court, District of ... dated January 20th, the Court has remanded a case ...
Breaking Medicine News(10 mins):Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4
... from anxiety and depression are more likely to report ... for the operation also entails significant costs to both ... the University of Gothenburg, Sweden. Drawing on around ... Arthroplasty Register, the thesis looks at how hip replacement ...
... (HealthDay News) -- Prayer can help victims of domestic ... coping methods such as venting, a small new study ... relationships who were interviewed by Shane Sharp, a sociology ... racially diverse participants came from different regions of the ...
... By Jenifer Goodwin HealthDay Reporter , TUESDAY, ... with wireless sensors, researchers simulated how the flu might spread ... three-quarters of a million opportunities for infection daily. Over ... staff came into close proximity of one another 762,868 times ...
... New Hampshire have received the first kidney transplants made possible ... Transplantation Network (OPTN) that uses a Carnegie Mellon University computer ... Ken Crowder of St. Louis and Kathy Niedzwiecki of ... donate a kidney but who were medically incompatible with them. ...
... Holohan HealthDay Reporter , MONDAY, Dec. 13 (HealthDay ... off Alzheimer,s disease, according to a new study that suggests ... disorder in older people. The study, published in the ... people who had low levels of high-density lipoprotein (HDL) or ...
... and women ages 50 to 64 stand to benefit ... access to affordable health insurance, assure that all health ... denying coverage or charging higher premiums to people with ... health insurance policies, according to a new Commonwealth Fund ...
Cached Medicine News:Health News:Expensive wait for hip replacements 2Health News:Prayer May Help Victims of Domestic Abuse 2Health News:Flu Spreads Easily in High Schools, Study Suggests 2Health News:Flu Spreads Easily in High Schools, Study Suggests 3Health News:2 people receive kidney transplants in pilot program using CMU software 2Health News:2 people receive kidney transplants in pilot program using CMU software 3Health News:What's Good for Heart May Also Be Good for Brain 2Health News:What's Good for Heart May Also Be Good for Brain 3Health News:18.3 million baby boomers could benefit from the Affordable Care Act 2Health News:18.3 million baby boomers could benefit from the Affordable Care Act 3Health News:18.3 million baby boomers could benefit from the Affordable Care Act 4
(Date:1/23/2015)... 2015  Now available for sale, The Armor1 Ankle Roll ... ankle sprains by cushioning the ankle from an inversion ... the outside of any shoe type and allows the ... offering protection against sprains. With customers in physical therapy, ...
(Date:1/23/2015)... 2015 Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC ...  filed a Preliminary Proxy Statement, Schedule 14A, with the U.S. ... an update for shareholders detailing why a "YES" vote to ... Dear Shareholders, As we reflect upon the 2014 ...
(Date:1/23/2015)... (NYSE: MNK ) announced today that its ... The open-ended authorization permits the company to repurchase up ... "Funding additional initiatives and seeking attractive business ... pursue a range of focused growth strategies," said ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... N.Y., Jan. 7 Misonix, Inc. (Nasdaq: MSON ), ... in Europe is used for the ablation of tumors and ... new, three year distribution agreement with Varlix Mexico, S.A. de ... the SonaStar(TM) Ultrasonic Surgical Aspirator and the BoneScalpel(TM) Ultrasonic Bone ...
... , FRANKLIN LAKES, N.J. , ... MHS ), on behalf of its affiliate companies and the ... critically needed generic medicines to assist in the global humanitarian relief ... , To ensure the medicines quickly reach those in need, Medco ...
Cached Medicine Technology:Misonix Announces New Distribution Agreement for Mexico 2Misonix Announces New Distribution Agreement for Mexico 3Medco Partners with AmeriCares to Rush Donated Medicines to Help Victims of the Haiti Earthquake 2Medco Partners with AmeriCares to Rush Donated Medicines to Help Victims of the Haiti Earthquake 3Medco Partners with AmeriCares to Rush Donated Medicines to Help Victims of the Haiti Earthquake 4
Blunt, with attached cable for Valleylab and other brands generators....
Blunt, 20 cm long....
Angulated, blunt tips....
... All Bovie LLETZ Loop ... wire for superior shape and ... They use a standard 3/32" ... loops are packaged in a ...
Medicine Products: