Navigation Links
Microbleeds important to consider in brain-related treatments, UCI neurologist says
Date:10/31/2013

Irvine, Calif., Oct. 31, 2013 As growing numbers of America's baby boomers reach retirement, neuroscientists are expanding their efforts to understand and treat one of the leading health issues affecting this population: age-related neurological deterioration, including stroke and dementia.

One factor coming under increased study is cerebral microbleeds, experienced by nearly 20 percent of people by age 60 and nearly 40 percent by age 80. Research into these small areas of brain bleeding, caused by a breakdown of miniscule blood vessels, is shedding light on how the condition may contribute to these neurological changes.

With microbleeds common in older individuals, physicians need to take it into consideration when treating other brain-related issues, said Dr. Mark Fisher, professor of neurology, anatomy & neurobiology, and pathology & laboratory medicine at UC Irvine. This is especially important with stroke prevention measures, which often involve medications that interfere with blood clotting and could exacerbate microbleeds. Stroke risk escalates with age, especially after 55, making stroke one of the leading causes of disability and death in the elderly.

In two current papers published online in Frontiers in Neurology and Stroke, Fisher writes about the brain's intricate system to protect itself against hemorrhaging. This system seems to break down as we get older, resulting in microbleeds that develop spontaneously and become increasingly common with aging.

"The next step in stroke prevention will require that we address both blood clotting and protection of the blood vessels," he said. "This seems to be the best way to reduce the risk of microbleeds when it's necessary to limit blood clotting for stroke prevention."

In his Stroke article, Fisher describes how newer medications interfere with blood clotting (to protect against stroke) while at the same time protecting the blood vessel wall (to help prevent bleeding). And in Frontiers in Neurology, he suggests that MRI screening be used more strategically to identify patients with microbleeds, allowing their physicians to adjust treatments accordingly.

"With the prevalence of microbleeds, it's important that we better understand this neurological factor as we develop and proceed with brain-related treatments for the elderly," Fisher said. "Identifying and controlling microbleeds may be an important step in a therapeutic approach to maximize brain health during the process of aging. This is a critical issue requiring further study."


'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Related medicine news :

1. COPD increases risk of developing cerebral microbleeds
2. Timing pregnancy an important health concern for women
3. Moffitt Cancer Center researchers: Quality of life as important as quantity of life
4. Joslin scientists identify important mechanism that affects the aging process
5. Higher hospital volume more important than surgeon experience in outcome of prostate cancer surgery
6. An important breakthrough in immunology by IRCM researchers
7. Timing of antibiotics important in reducing infections after C-section
8. Cancer turns off important immune cells, complicating experimental vaccine therapies
9. Government can play important role in obesity epidemic
10. Environmentally friendly chemistry important for manufacturing pharmaceuticals
11. JTCC researchers play important role in groundbreaking study that may change transplant practices
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... to revolutionize the emergency ambulance transport experience for the millions of people who ... Uber has disrupted the taxi industry through the use of technology. Now, SmartEMS ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)...  MedSource announced today that it has selected ... of choice.  This latest decision demonstrates MedSource,s commitment ... clients by offering a state-of-the-art electronic data capture ... as the EDC platform of choice in exchange ... has long been a preferred EDC platform by ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
Breaking Medicine Technology: