Navigation Links
Microbiomes may hold key to better understanding of preterm birth
Date:9/28/2010

ROCHESTER, Minn. -- A team of scientists from Mayo Clinic, the University of Illinois at Urbana-Champaign, and the J. Craig Venter Institute are leveraging a long-standing research relationship to apply results from the Human Microbiome Project to help identify microbial risk predictors for preterm birth.

"This is a collaborative effort to apply cutting-edge technology to one of the fundamental problems in maternal-fetal health," says Douglas Creedon, M.D., Ph.D., Mayo Clinic obstetrician and gynecologist. The project also represents the first major initiative of the newly formed Mayo-Illinois Strategic Alliance for Technology-Based Health Care.

"Bacterial vaginosis affects between 10 and 15 percent of women of reproductive age and is associated with a host of genital tract infections and pregnancy complications," says lead researcher Bryan White, Ph.D., a professor of animal science at Illinois. "Our ultimate goal is to use the wealth of genomic information from the Human Microbiome Project to improve women's health." The Human Microbiome Project is an NIH program to identify and catalog the microbes within the human body and determine their impact on health.

Drs. White and Creedon, along with co-leader Brenda Wilson, Ph.D., an associate professor of microbiology at Illinois, and Karen Nelson, Ph.D., and Derrick Fouts, Ph.D., at the J. Craig Venter Institute, will use the emerging microbiome, metagenome, and reference genome datasets to characterize the microbiomes associated with urogenital infections. These include bacterial vaginosis, urinary tract infection and yeast vaginitis, which afflict over 1 billion women each year.

The project, entitled "The human vaginal microbiome and bacterial vaginosis," will explore the complex relationship between vaginal microbiota and humans. Scientists are particularly interested in the link between the vaginal infection and preterm birth, as microbiologic evidence suggests that infection may contribute to approximately 25 percent of preterm births.

"In most cases of preterm labor and delivery, intrauterine infection is not clinically apparent," Dr. White says. "But there seems to be a strong correlation between infection and premature birth. We see colonization rates as high as 79 percent for birth at 23 weeks of gestation, yet they decline to 11 percent at 31 to 34 weeks."


'/>"/>

Contact: Robert Nellis
nellis.robert@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Friends, family detect early Alzheimers signs better than traditional tests
2. Better marker for breast cancer may reduce need for second surgeries
3. Prostate cancer community calls for better early detection and treatment
4. What can health-care facilities do to help patients better understand medical information
5. Centralized health care more cost-effective, offers better access to preventive services
6. University of Colorado Denver Business School study shows failure better teacher than success
7. Drug addicts get hooked via prescriptions, keep using to feel like a better person, research shows
8. Moderate drinking, especially wine, associated with better cognitive function
9. Better understanding of mapmaking in the brain
10. Surgery better than radiation, hormone treatments for some prostate cancer, study shows
11. Colitis patients diagnosed later in life tend to have better disease outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2017)... , ... April 26, 2017 , ... ... in Hackensack, N.J. has been honored by Enterprising Women magazine as one of ... the world’s top women business owners. Winners have demonstrated that they have fast-growth ...
(Date:4/26/2017)... ... April 26, 2017 , ... Want to learn more ... CRISPRCas.pioneer.com ) that demonstrates how this advanced plant breeding technology is a more ... with fewer resources. It highlights the business’ principles, research and collaboration efforts in ...
(Date:4/25/2017)... ... April 25, 2017 , ... Splashtop ... Mirroring360 Pro . This new addition to the Mirroring360 product family combines device ... business. , Mirroring360 Pro enables educators, business professionals and individuals to stream or ...
(Date:4/25/2017)... ... 25, 2017 , ... A recent report from the Wisconsin ... the 2015-16 school year across Wisconsin’s public schools, charter schools, and private schools ... in student test score performance, the report’s limited analyses fail to provide answers ...
(Date:4/25/2017)... ... April 25, 2017 , ... ... in unveiling cutting-edge birth defects research related to Zika virus during pregnancy, as ... premier society for this important science. , The Teratology Society ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017 Global Surgical Drainage Device Market: Overview ... to remove excess liquid and air. The fluid to ... or lymph. Surgical drains are used in a wide ... surgery, cardiovascular surgery, neurosurgery, plastic surgery etc. Common use ... accumulation of fluid e.g. blood or pus. Surgical drains ...
(Date:4/19/2017)... , April 19, 2017 ... stimulate an immune response in pets such as ... products are of various types such as Attenuated ... Toxoid Vaccines, DNA Vaccines and Recombinant Vaccines. Attenuated ... as virus or bacteria, which have been weakend ...
(Date:4/18/2017)... , April 18, 2017 Cogentix Medical, ... on providing the Urology, Uro/Gyn and Gynecology markets with ... the first quarter ended March 31, 2017 after the ... The Company will host a conference call and ... on Tuesday, May 2, 2017 at 4:30 p.m. Eastern ...
Breaking Medicine Technology: