Navigation Links
Microbiomes may hold key to better understanding of preterm birth
Date:9/28/2010

ROCHESTER, Minn. -- A team of scientists from Mayo Clinic, the University of Illinois at Urbana-Champaign, and the J. Craig Venter Institute are leveraging a long-standing research relationship to apply results from the Human Microbiome Project to help identify microbial risk predictors for preterm birth.

"This is a collaborative effort to apply cutting-edge technology to one of the fundamental problems in maternal-fetal health," says Douglas Creedon, M.D., Ph.D., Mayo Clinic obstetrician and gynecologist. The project also represents the first major initiative of the newly formed Mayo-Illinois Strategic Alliance for Technology-Based Health Care.

"Bacterial vaginosis affects between 10 and 15 percent of women of reproductive age and is associated with a host of genital tract infections and pregnancy complications," says lead researcher Bryan White, Ph.D., a professor of animal science at Illinois. "Our ultimate goal is to use the wealth of genomic information from the Human Microbiome Project to improve women's health." The Human Microbiome Project is an NIH program to identify and catalog the microbes within the human body and determine their impact on health.

Drs. White and Creedon, along with co-leader Brenda Wilson, Ph.D., an associate professor of microbiology at Illinois, and Karen Nelson, Ph.D., and Derrick Fouts, Ph.D., at the J. Craig Venter Institute, will use the emerging microbiome, metagenome, and reference genome datasets to characterize the microbiomes associated with urogenital infections. These include bacterial vaginosis, urinary tract infection and yeast vaginitis, which afflict over 1 billion women each year.

The project, entitled "The human vaginal microbiome and bacterial vaginosis," will explore the complex relationship between vaginal microbiota and humans. Scientists are particularly interested in the link between the vaginal infection and preterm birth, as microbiologic evidence suggests that infection may contribute to approximately 25 percent of preterm births.

"In most cases of preterm labor and delivery, intrauterine infection is not clinically apparent," Dr. White says. "But there seems to be a strong correlation between infection and premature birth. We see colonization rates as high as 79 percent for birth at 23 weeks of gestation, yet they decline to 11 percent at 31 to 34 weeks."


'/>"/>

Contact: Robert Nellis
nellis.robert@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Friends, family detect early Alzheimers signs better than traditional tests
2. Better marker for breast cancer may reduce need for second surgeries
3. Prostate cancer community calls for better early detection and treatment
4. What can health-care facilities do to help patients better understand medical information
5. Centralized health care more cost-effective, offers better access to preventive services
6. University of Colorado Denver Business School study shows failure better teacher than success
7. Drug addicts get hooked via prescriptions, keep using to feel like a better person, research shows
8. Moderate drinking, especially wine, associated with better cognitive function
9. Better understanding of mapmaking in the brain
10. Surgery better than radiation, hormone treatments for some prostate cancer, study shows
11. Colitis patients diagnosed later in life tend to have better disease outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
Breaking Medicine Technology: