Navigation Links
Microbiomes may hold key to better understanding of preterm birth
Date:9/28/2010

ROCHESTER, Minn. -- A team of scientists from Mayo Clinic, the University of Illinois at Urbana-Champaign, and the J. Craig Venter Institute are leveraging a long-standing research relationship to apply results from the Human Microbiome Project to help identify microbial risk predictors for preterm birth.

"This is a collaborative effort to apply cutting-edge technology to one of the fundamental problems in maternal-fetal health," says Douglas Creedon, M.D., Ph.D., Mayo Clinic obstetrician and gynecologist. The project also represents the first major initiative of the newly formed Mayo-Illinois Strategic Alliance for Technology-Based Health Care.

"Bacterial vaginosis affects between 10 and 15 percent of women of reproductive age and is associated with a host of genital tract infections and pregnancy complications," says lead researcher Bryan White, Ph.D., a professor of animal science at Illinois. "Our ultimate goal is to use the wealth of genomic information from the Human Microbiome Project to improve women's health." The Human Microbiome Project is an NIH program to identify and catalog the microbes within the human body and determine their impact on health.

Drs. White and Creedon, along with co-leader Brenda Wilson, Ph.D., an associate professor of microbiology at Illinois, and Karen Nelson, Ph.D., and Derrick Fouts, Ph.D., at the J. Craig Venter Institute, will use the emerging microbiome, metagenome, and reference genome datasets to characterize the microbiomes associated with urogenital infections. These include bacterial vaginosis, urinary tract infection and yeast vaginitis, which afflict over 1 billion women each year.

The project, entitled "The human vaginal microbiome and bacterial vaginosis," will explore the complex relationship between vaginal microbiota and humans. Scientists are particularly interested in the link between the vaginal infection and preterm birth, as microbiologic evidence suggests that infection may contribute to approximately 25 percent of preterm births.

"In most cases of preterm labor and delivery, intrauterine infection is not clinically apparent," Dr. White says. "But there seems to be a strong correlation between infection and premature birth. We see colonization rates as high as 79 percent for birth at 23 weeks of gestation, yet they decline to 11 percent at 31 to 34 weeks."


'/>"/>

Contact: Robert Nellis
nellis.robert@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Friends, family detect early Alzheimers signs better than traditional tests
2. Better marker for breast cancer may reduce need for second surgeries
3. Prostate cancer community calls for better early detection and treatment
4. What can health-care facilities do to help patients better understand medical information
5. Centralized health care more cost-effective, offers better access to preventive services
6. University of Colorado Denver Business School study shows failure better teacher than success
7. Drug addicts get hooked via prescriptions, keep using to feel like a better person, research shows
8. Moderate drinking, especially wine, associated with better cognitive function
9. Better understanding of mapmaking in the brain
10. Surgery better than radiation, hormone treatments for some prostate cancer, study shows
11. Colitis patients diagnosed later in life tend to have better disease outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... ... February 22, 2017 , ... Using the power of the internet, IdrisArkette.com ... checklist. Over a period of just 24 months, thousands of individuals interested in a ... called T.A.D. , “The internet is not getting quieter. In fact it’s becoming noisier ...
(Date:2/22/2017)... Beach, FL (PRWEB) , ... February 22, 2017 , ... ... Wrestling Legend Kurt Angle, is now available on the App Store and ... and award-winning mobile apps for the addiction and recovery industry, partnered with Angle to ...
(Date:2/22/2017)... ... February 22, 2017 , ... ... to spine practices, is featuring Michigan neurosurgeon Jay Jagannathan, M.D., as a “Spine ... a small number of neurosurgeons in Michigan performing minimally invasive back surgery that ...
(Date:2/22/2017)... ... 22, 2017 , ... A product of digesting a micronutrient found in soy ... from eating soy foods, while others do not, a University of Pittsburgh Graduate School ... equol—a substance made by some types of “good” gut bacteria when they metabolize isoflavones ...
(Date:2/22/2017)... , ... February 22, 2017 , ... ... and 72 percent of those report that family members or friends have also ... they suffer from hearing loss wear hearing aids. One reason, suggested by 89 ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... 2017 Merrimack Pharmaceuticals, Inc. (Nasdaq: MACK ... Quarter 2016 investor conference call and webcast at 8:30 a.m., ... call will cover an update on Merrimack,s recent progress as ... 2016 financial results. A press release detailing the information to ... of Wednesday, March 1. Investors and the general public are ...
(Date:2/22/2017)... , Feb. 22, 2017 Summary ... heart failure partnering deals and agreements entered into ... the full report: http://www.reportlinker.com/p03605673-summary/view-report.html Description ... report provides understanding and access to partnering deals ... healthcare companies. - Trends in partnering ...
(Date:2/22/2017)... NEW YORK , Feb. 22, 2017 ... non-small cell lung cancer partnering deals and agreements entered ... the full report: http://www.reportlinker.com/p03605668-summary/view-report.html Description The ... since 2010 report provides understanding and access to partnering ... healthcare companies. - Trends in partnering deals ...
Breaking Medicine Technology: