Navigation Links
Microarray provides 3 genomic guides to breast cancer treatment decisions
Date:9/7/2007

HOUSTON - Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional treatment, and the cancer's vulnerability to chemotherapy or hormone therapy, researchers at The University of Texas M. D. Anderson Cancer Center report at the first American Society of Clinical Oncology ASCO Breast Cancer Symposium Sept. 7-8 in San Francisco.

Each predictor - of prognosis, of sensitivity to chemotherapy and sensitivity to hormone therapy - is independent of the others, providing unique information to physicians and patients considering treatment options, says W. Fraser Symmans, M.D., professor in M. D. Anderson's Department of Pathology.

"Existing genomic tests for breast cancer provide information about future risk in general, but not the likely benefit of each treatment option separate from a patient's overall prognosis if no treatment followed surgery. It is important to independently assess these three variables," Symmans says.

Symmans and Lajos Pusztai, M.D., Ph.D., associate professor in M. D. Anderson's Department of Breast Medical Oncology will present two research updates on the genomic predictors, which can be reported from a single microarray analysis of a needle biopsy of a patient's breast cancer.

Symmans will present results from two studies involving 960 patients validating a 200-gene index that predicts a patient's response to hormone-suppressing therapy. About 70 percent of breast cancers express the estrogen receptor (ER), indicating that their growth is fueled to some extent by the female hormone estrogen. Anti-estrogen therapies such as tamoxifen only benefit about half of these patients. The challenge is to predict exactly who will be helped and who should seek additional treatment.

In the two studies the Sensitivity to Endocrine Therapy (SET) Index score predicted distant relapse free survival among 453 patients who received tamoxifen
'/>"/>

Contact: Scott Merville
sdmervil@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Acupuncture provides relief
2. Micro-camera provides new breast imaging technique
3. MicroRNA provides new insight into birth defects
4. Hormone therapy provides no heart benefit
5. Drug Spironolactone Provides Renal And Cardioprotection In Diabetic Patients
6. Neurobiology Provides Answers To Block Memory-Related Drug Cravings
7. Cholesterol provides immunity against infection by certain parasites
8. John Hopkins CGHH program provides Global Health education
9. Protein provides antioxidant protection to Neurons
10. London Hospital Provides Specialized Care For Pregnant Women
11. Study Provides Evidence That Obesity Leads To A More Aggressive Ovarian Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... FL (PRWEB) December 26, 2014 India ... health insurance in the USA, announced today a new ... assist members in choosing the right plan for their ... the complexity out of the selection process when choosing ... by age group with only a few clicks. Many ...
(Date:12/25/2014)... The microscopy market is estimated ... reach $5,756.0 million by 2019. Optical microscopy is ... electron microscopes product segment is expected to show ... Rising focus on nanotechnology, technological advancements, and increasing ... market. , Get Full Copy of Report @ ...
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... Analysis to 2023” focuses on the current treatment landscape, ... colorectal cancer market. TS-1 is an anti-cancer drug which ... administered orally and is also used for treating gastric ... gimestat and otastat potassium. The drug was first approved ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying women’s ... discounted prom dresses, most of which are priced under ... company, the promotion is valid until Jan. 22, 2015; ... UK market. , The prom dresses in this new ... A-line strapless, empire strapless chiffon, one shoulder, floor-length, V-neck ...
(Date:12/25/2014)... Woodland Hills, California (PRWEB) December 25, 2014 ... in her home in Woodland Hills, California after an ... Harris passed away on Christmas Eve evening in her ... battle with aggressive metastatic breast cancer. ... International for over forty years, she pioneered and championed ...
Breaking Medicine News(10 mins):Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 2Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 3Health News:Microscopy Market Hit to $5,756.0 Million by 2019 - New Research Report by MarketsandMarkets 4Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4
... medical aid organization sends critically needed supplies to ... clinics, fire and rescue in ... Direct Relief,International today increased emergency medical supplies to safety-net,clinics ... in,Southern California, where uncontained fires have forced 500,000 people ...
... 23 Pfizer Inc announced today that its,La Jolla ... 1,000,scientists and staff to cope with San Diego County,s ... day-to-day,analysis of information from the many agencies involved in ... in areas impacted by the fires so it,s,important that ...
... WASHINGTON, Oct. 23 Pharmaceutical Research and,Manufacturers of ... the,following statement regarding the California wildfires: "Californians ... -- and who,are uninsured or underinsured -- should ... be available through the Partnership for,Prescription Assistance. The ...
... WASHINGTON, Oct. 23 The Department of,Veterans Affairs (VA) ... veterans even as wildfires burn across parts of Southern,California., ... damaged or directly,threatened," said Acting Secretary of Veterans Affairs ... our patients and staff.", The San Diego VA ...
... guide the company,s strategic efforts, KNOXVILLE, Tenn., ... innovator in providing comprehensive plan design,and management technology, ... of Health Value Innovation and former vice president ... Board of Directors. "Today,s self insured employers ...
... HealthShares(TM) Inc., an investment,company with a series ... been informed by Standard & Poor,s, the calculating ... opening of trading on,Friday, October 26, 2007, Immunogen, ... (Nasdaq: BIVN ) in the HealthShares(TM) Emerging ...
Cached Medicine News:Health News:Direct Relief International Aims California Fire Response at Health Concerns 2Health News:Help for California Fire Evacuees Possible Through Partnership for Prescription Assistance 2Health News:Leading Authority on Health Benefits, David Hom, Joins Board of Directors of Healthcare Technology Innovator, NavigatorMD, Inc. 2Health News:Leading Authority on Health Benefits, David Hom, Joins Board of Directors of Healthcare Technology Innovator, NavigatorMD, Inc. 3Health News:HealthShares(TM) Announces Change to the HealthShares(TM) Emerging Cancer Index 2Health News:HealthShares(TM) Announces Change to the HealthShares(TM) Emerging Cancer Index 3
(Date:12/24/2014)... 2014 ResMed (NYSE: RMD ) today ... Chinese medical device manufacturer BMC Medical Co., Ltd. ... masks listed below infringe ResMed,s patents, and entered an order ... the United States : , ... , Willow nasal pillows mask , iVolve full face ...
(Date:12/24/2014)... ALEXANDRIA, Va. , Dec. 23, 2014 /PRNewswire-USNewswire/ ... stringent diastolic blood pressure target for people with ... either moderate or high doses of statins, in ... risk management enacted by the American College of ... recommendations are reflected in the most recent changes ...
(Date:12/22/2014)... 22, 2014  CytoSorbents Corporation (OTCQB:CTSOD), a critical ... purification technology to help fight deadly inflammation in ... worldwide, today announced the appointment of Dr. ... its Senior Vice President of Clinical Development, effective ... Di Russo is an accomplished pediatric cardiothoracic ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... Oramed Pharmaceuticals Inc. (OTC BB: ORMP.OB) ... announced today that Ehud Arbit, M.D., the Director of ... 8th Annual Israel Strategic Partner and Venture Conference. The ... Research Institute in Princeton, NJ on September 22, 2011. ...
... care costs are increasing, but NeedyMeds.org today ... while staying healthy. NeedyMeds.org is a not-for-profit ... prescription medications and other medical needs.  Consumer can visit ... and Spanish regarding cost savings on prescription drugs that ...
Cached Medicine Technology:Oramed Pharmaceuticals Chosen to Present at the 8th Annual Israel Strategic Partner and Venture Conference on September 22, 2011 2Non-Profit Offers 3 Easy Consumer Tips to Save on Prescriptions 2
Natural eye color change for even the darkest of eyes....
An entirely new way to brighten and enhance natural eye color....
Breakthrough technology creates a remarkably natural look. Blends 3 colors into one to create the subtle, natural depth of beautiful eyes....
Disposable-type color lenses for exciting eye color change....
Medicine Products: