Navigation Links
MicroRNA controls mammary gland development in mice
Date:11/9/2010

gland, which is also known as the milk gland, consists of the milk ducts and the surrounding connective tissue, which has a supportive and regulatory function. The connective tissue also appears to be the location where miR-212 and miR-132 are produced and intervene in the developmental process. Chowdhury and his colleague Ahmet Ucar were able to demonstrate with their experiments that this is the only place where the genes for these ribonucleic acid molecules are "switched on" in the breast tissue.

Molecular dimmer

According to the researcher's model, the microRNA molecules appear to control the production of a protein called MMP-9. "The microRNAs can down-regulate the production of MMP-9, like a dimmer switch," explains Ucar. If the microRNAs are missing, more MMP-9 proteins are produced and they accumulate near the milk ducts. They appear to activate a signalling pathway there, which prevents the normal growth of the milk ducts in the glandular tissue. "These tiny RNA molecules carry out their regulatory function by influencing the communication between the two tissues of the mammary gland," says Ucar. Other experiments now need to be carried out to examine whether these microRNAs also regulate breast development in humans. At the moment, the scientists can only speculate about what happens when the microRNAs do not function correctly. "Whether such malfunctions can lead to the formation of tumours, for example, is something that needs to be examined in further studies," says Chowdhury.


'/>"/>

Contact: Kamal Chowdhury
kchowdh@gwdg.de
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Caltech biologists discover microRNAs that control function of blood stem cells
2. MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
3. Cancer cells show rewired, fragmented microRNA networks
4. Study links microRNA to shut-down of DNA-repair genes
5. Scientists identify microRNA as possible cause of chemotherapy resistance
6. UCLA cancer researchers discover new signaling pathway that controls cell development and cancer
7. FDA accepts historical controls for epilepsy monotherapy studies
8. Scripps Research scientists uncover previously unknown natural mechanism that controls cocaine use
9. TPG Capital Selects MetricStream GRC Platform to Boost its Internal Controls and Compliance
10. Study finds key protein controls T-cell proliferation
11. PCMA: Federal Enrollees Don't Want Congress to Reduce Pharmacy Choices, Impose Price Controls in FEHBP
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MicroRNA controls mammary gland development in mice
(Date:5/3/2015)... CA (PRWEB) May 03, 2015 NuevaCare ... MnemeTherapy® at two upcoming area seminars. The first event ... PSA Annual Regional Stroke Conference to be held at ... offered on Wednesday, May 13 during the Dementia Conference ... , “These seminars offer an excellent opportunity to ...
(Date:5/3/2015)... 2015 HealthPostures, a pioneering ergonomics ... its appearance at the , May 5 - 7, ... will exhibit at the conference include its bestselling TaskMate ... solutions is the 6100 TaskMate Executive. Features of the ... adjustable keyboard tray, extended platform work surface and supply ...
(Date:5/2/2015)... BC (PRWEB) May 02, 2015 Vancouver fencing ... will now provide valuable advice to prospective clients related to ... are looking to install railings around their decks and patios. ... several questions that pop up once the person rolls up ... phases of installing a railing in finding a gate that ...
(Date:5/2/2015)... It’s a pattern that won’t relent anytime ... on this planet, cyber scammers will immediately be thinking ... their own personal gain. And on April 30, ... issued an alert titled “Nepal Earthquake Disaster Email Scams,” ... earthquake in Nepal. The scam emails may contain links ...
(Date:5/2/2015)... On Tuesday April 7th, the patient care ... celebrate improvements in patient care. In 2014 the hospital, ... zero acquired ventilator associated infections, zero central line associated ... also recently named a Top Performer by the Joint ... the teamwork of staff from all departments involved in ...
Breaking Medicine News(10 mins):Health News:NuevaCare Introduces MnemeTherapy® Approach to Care for Elderly Patients with Alzheimer’s, Stroke and Other Types of Neurodegenerative Conditions 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2
... are planning to study the relationship between global warming ... will be funded by the U.S. Centers for Disease ... individuals have died due to the heat wave that ... track the rising temperature to these illness and deaths ...
... have seen evident improvement in the death rates of Aborigines ... benefits of improved healthcare that has brought down death rates ... of funds into healthcare will see far more results in ... and quality of life., ,The study's leader, David ...
... of graphic pictures on cigarette packets, Benson and Hedges, a ... reinventing the packaging of cigarettes in tins which carry health ... removed. , ,Action on Smoking and Health (ASH) ... for inventing ways to reduce the impact of health warnings ...
... Reports have indicated that doctors in the US U.S. ... the condition, leaving some patients to suffer for years.// ... diseases in the world, and according to the World ... million in the year 2004. A tuberculosis bacterium has ...
... FDA-approved tool to treat drug-resistant HIV thanks to a ... ,"There are many treatments for AIDS on the market, ... Arun Ghosh (pronounced A-rune GO-sh), a professor with a ... chemistry and molecular pharmacology. "This is the first treatment ...
... women with endometrial cancer should be screened for inherited ... several other cancers.// ,The study showed that ... diagnosed endometrial cancer patients have mutations for Lynch syndrome, ... cancer, or HNPCC. ,People with Lynch syndrome ...
Cached Medicine News:Health News:Doctors In US Lack Skills For The Diagnosis Of TB 2Health News:Research Leads to First Treatment for Drug-Resistant HIV 2Health News:Research Leads to First Treatment for Drug-Resistant HIV 3Health News:Research Leads to First Treatment for Drug-Resistant HIV 4Health News:Uterine Cancer May be Clue to Inherited Syndrome 2Health News:Uterine Cancer May be Clue to Inherited Syndrome 3
(Date:5/1/2015)... May 1, 2015 Braeburn Pharmaceuticals ... current therapeutic focus beyond addiction and pain ... disorders. Braeburn has acquired an implantable, six-month ... risperidone for treatment of schizophrenia from Endo ... global rights to other potential applications of ...
(Date:5/1/2015)... May 1, 2015  Boston Scientific Corporation (NYSE: ... business momentum and long-term growth strategies at a meeting ... York City . President and Chief Executive Officer ... the company has to bring forward meaningful innovation to ... and deliver shareholder value. "We are ...
(Date:5/1/2015)... Cambrex Corporation (NYSE: CBM ) reports results for the ... , Sales increased 18% compared to the first ... driven by Innovator products and Controlled Substances. , EBITDA ... quarter of 2014. , GAAP Diluted EPS from continuing ... year and Adjusted Diluted EPS was $0.29 compared to $0.07 ...
Breaking Medicine Technology:Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 2Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 3Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 4Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 5Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 6Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 7Cambrex Reports First Quarter 2015 Financial Results 2Cambrex Reports First Quarter 2015 Financial Results 3Cambrex Reports First Quarter 2015 Financial Results 4Cambrex Reports First Quarter 2015 Financial Results 5Cambrex Reports First Quarter 2015 Financial Results 6Cambrex Reports First Quarter 2015 Financial Results 7Cambrex Reports First Quarter 2015 Financial Results 8Cambrex Reports First Quarter 2015 Financial Results 9Cambrex Reports First Quarter 2015 Financial Results 10Cambrex Reports First Quarter 2015 Financial Results 11
... drug used to treat erectile dysfunction and pulmonary ... and young adults with congenital heart disease to ... exercise performance during stress testing in patients with ... Children,s Hospital of Philadelphia. This study ...
... American Medical Systems® (AMS) (Nasdaq: AMMD ), ... male and female pelvic health, today announced the results ... Anterior and Apical Prolapse Repair System. The pelvic organ ... stage pelvic support, was implemented in the study and ...
Cached Medicine Technology:Exercise Performance in Children and Young Adults with Single Ventricle Heart Disease Improves with Use of Drug for Erectile Dysfunction 2Exercise Performance in Children and Young Adults with Single Ventricle Heart Disease Improves with Use of Drug for Erectile Dysfunction 3Six-Month Prospective Multi-Center Study Reports Efficacy Rates for AMS' Elevate Anterior and Apical Prolapse Repair System 2
... well as humidification, try Flo-Mist™., ,Flo-Mist™, ... continuous medication nebulizer (CMN), engineered to deliver ... ml reservoir and jet flow design allow ... medication delivery at 25 ml/hr. Particles are ...
... Innovators in Anesthesia and Respiratory Products, ... medical devices for Anesthesia and Respiratory professionals. ... products that enhance the clinician's ability to ... attention to the bottom line. , ...
... Why design a nebulizer for this age ... coordinating inspiratory effort with actuation of an MDI. ... minimum inspiratory flow rate to achieve efficiency. , ... efficiency. , ,Blowby techniques often used for ...
... The new PARI TREK™ Compact Compressor ... take their aerosol treatments anywhere and everywhere. ... powerful. Three versatile power source optionsworldwide AC ... and rechargeable battery, permit patients the freedom ...
Medicine Products: