Navigation Links
MicroRNA controls mammary gland development in mice
Date:11/9/2010

gland, which is also known as the milk gland, consists of the milk ducts and the surrounding connective tissue, which has a supportive and regulatory function. The connective tissue also appears to be the location where miR-212 and miR-132 are produced and intervene in the developmental process. Chowdhury and his colleague Ahmet Ucar were able to demonstrate with their experiments that this is the only place where the genes for these ribonucleic acid molecules are "switched on" in the breast tissue.

Molecular dimmer

According to the researcher's model, the microRNA molecules appear to control the production of a protein called MMP-9. "The microRNAs can down-regulate the production of MMP-9, like a dimmer switch," explains Ucar. If the microRNAs are missing, more MMP-9 proteins are produced and they accumulate near the milk ducts. They appear to activate a signalling pathway there, which prevents the normal growth of the milk ducts in the glandular tissue. "These tiny RNA molecules carry out their regulatory function by influencing the communication between the two tissues of the mammary gland," says Ucar. Other experiments now need to be carried out to examine whether these microRNAs also regulate breast development in humans. At the moment, the scientists can only speculate about what happens when the microRNAs do not function correctly. "Whether such malfunctions can lead to the formation of tumours, for example, is something that needs to be examined in further studies," says Chowdhury.


'/>"/>

Contact: Kamal Chowdhury
kchowdh@gwdg.de
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Caltech biologists discover microRNAs that control function of blood stem cells
2. MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
3. Cancer cells show rewired, fragmented microRNA networks
4. Study links microRNA to shut-down of DNA-repair genes
5. Scientists identify microRNA as possible cause of chemotherapy resistance
6. UCLA cancer researchers discover new signaling pathway that controls cell development and cancer
7. FDA accepts historical controls for epilepsy monotherapy studies
8. Scripps Research scientists uncover previously unknown natural mechanism that controls cocaine use
9. TPG Capital Selects MetricStream GRC Platform to Boost its Internal Controls and Compliance
10. Study finds key protein controls T-cell proliferation
11. PCMA: Federal Enrollees Don't Want Congress to Reduce Pharmacy Choices, Impose Price Controls in FEHBP
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MicroRNA controls mammary gland development in mice
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... neuroscientist, professor of cognitive sciences at the University of ... National Institute of //Deafness and Other Communication Disorders (NIDCD) ... ($2.4 million for 5 years). ,This will ... converts sound waves into meaningful language. ,This ...
... are flooded with patients with psychiatric disorders. The number of ... the past 4 years. ,This shows us ... ,According to the Australian Institute of Health and ... hospitals decreased by 5%. ,But the pressure on ...
... to analyze the fluctuations in eating and exercise habits ... different seasons with a tendency to eat more during ... that there is a corresponding seasonal change in the ... Massachusetts Medical School in Worcester have conducted the study. ...
... in Kenya’s west, and she ensures that the HIV patients in ... regard to the disease. The chief difficulty // for those ... finding a person who will take care of the patient, and ... to consume. ,Volunteers help the nurses and doctors ...
... the health officials to reduce the waiting list of patients ... ,Hence new methods are being adopted by increasing the ... ,Consultants receive more than ?1,500 a day from officials ... patients will receive appointments within 6 months after their reference ...
... Drugs and Crimes (UNODC) fears that that the survivors of ... Afghanistan might turn to drugs to provide succor from their ... launched a series of workshops in collaboration with the Pakistani ... UNODC said that the agency had increasingly taken note of ...
Cached Medicine News:Health News:$2.4 Million Grant To Unravel The Mystery Of Language Recognition. 2Health News:Community hospitals inundated with Psychiatric care cases (12%) 2Health News:Seasonal Variation In Exercise And Eating Habits Identified 2Health News:Surgeons being paid triple the amount to cut waiting lists 2
(Date:12/24/2014)... ResMed (NYSE: RMD ) today announced ... medical device manufacturer BMC Medical Co., Ltd. ... listed below infringe ResMed,s patents, and entered an order prohibiting ... the United States : , iVolve ... Willow nasal pillows mask , iVolve full face mask ...
(Date:12/24/2014)... Ohio , Dec. 23, 2014   ... treatment decision support to healthcare providers for behavioral ... it has secured $30 million in equity financing ... Virginia C. Drosos , President and Chief Executive ... clinical adoption and development of Assurex Health,s ...
(Date:12/24/2014)... , Dec. 23, 2014 Tianyin Pharmaceutical ... that specializes in patented biopharmaceutical, modernized traditional Chinese ... (API) today announced that the Company achieved the ... Manufacturing Practice (GMP) certificate of TPI,s Qionglai Facility ... (CFDA). The public notice period is a significant ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 2Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 3Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 4TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3
... cleared device to identify the, lipid core (fatty) coronary ... ... BURLINGTON, Mass., May 15 InfraReDx, Inc. today,announced that physicians ... LipiScan(TM) Coronary Imaging System in a patient,undergoing a cardiac catheterization. ...
... Pharma today,announced that the United States Food and ... Terguride for the treatment of pulmonary,arterial hypertension (PAH). ... pivotal Phase II trial in Europe., "The ... for PAH,encourages and strengthens our development program by ...
Cached Medicine Technology:First Use in a Patient of The InfraReDx LipiScan(TM) Coronary Imaging System 2First Use in a Patient of The InfraReDx LipiScan(TM) Coronary Imaging System 3First Use in a Patient of The InfraReDx LipiScan(TM) Coronary Imaging System 4Terguride Receives FDA Orphan Drug Designation for the Treatment of Pulmonary Arterial Hypertension 2
... Ankle/Brachial Index (ABI) testing, Nicolet Vascular has ... It includes a 10-minute compact disk ABI ... any computer with a CD drive. It ... ABI test, provides information on the materials ...
... Triad Skull Clamp, compatible with the full ... of clamping force on all three skull ... the possibility of adjusting the force on ... be increased or decreased by adjusting the ...
... Advanced engineering, rapid acquisition of data, ... it the most accurate autorefractor available. ... High Quality Monitor allows for easy ... are taken as soon as focus ...
... Clinitek Microalbumin Strips provide albumin, creatinine and ... Clinitek Microalbumin product is useful to test ... hypertension in order to detect early kidney ... of the urinary albumin excretion rate, is ...
Medicine Products: