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Michael J. Fox Foundation Launches Rapid Response Innovation Awards 2008 Following Strong Inaugural Year Response
Date:12/12/2007

rovision of institutional documents and sign the award contract.

Projects funded in 2008 include:

-- A project testing whether isradipine, a high-blood-pressure drug

already approved for use in humans, protects dopamine neurons in an

animal model of Parkinson's disease;

-- Development of nanoparticle technology as a non-viral gene therapy

technique that could help overcome the delivery challenges of getting

PD therapeutics past the blood-brain barrier;

-- A project to test the Braak Hypothesis, which posits that sporadic

Parkinson's may begin not in the central nervous system but in the

enteric, or gastrointestinal, nervous system -- knowledge that would

provide revolutionary insights into the pathogenesis and progression

of PD; and

-- Initial work to determine whether low levels of a gene called ST13

predict risk of future PD (which could lead to the development of

a practical, widely available blood test for early and objective

diagnosis of Parkinson's disease).

A complete list of projects funded under RRIA 2007, including researcher bios and grant abstracts, is available at http://www.michaeljfox.org.

Founded in 2000, The Michael J. Fox Foundation for Parkinson's Research is dedicated to ensuring the development of a cure for Parkinson's disease within this decade through an aggressively funded research agenda. The Foundation has funded $100 million in research to date.


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SOURCE Michael J. Fox Foundation
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