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Michael J. Fox Foundation Launches Rapid Response Innovation Awards 2008 Following Strong Inaugural Year Response

rovision of institutional documents and sign the award contract.

Projects funded in 2008 include:

-- A project testing whether isradipine, a high-blood-pressure drug

already approved for use in humans, protects dopamine neurons in an

animal model of Parkinson's disease;

-- Development of nanoparticle technology as a non-viral gene therapy

technique that could help overcome the delivery challenges of getting

PD therapeutics past the blood-brain barrier;

-- A project to test the Braak Hypothesis, which posits that sporadic

Parkinson's may begin not in the central nervous system but in the

enteric, or gastrointestinal, nervous system -- knowledge that would

provide revolutionary insights into the pathogenesis and progression

of PD; and

-- Initial work to determine whether low levels of a gene called ST13

predict risk of future PD (which could lead to the development of

a practical, widely available blood test for early and objective

diagnosis of Parkinson's disease).

A complete list of projects funded under RRIA 2007, including researcher bios and grant abstracts, is available at

Founded in 2000, The Michael J. Fox Foundation for Parkinson's Research is dedicated to ensuring the development of a cure for Parkinson's disease within this decade through an aggressively funded research agenda. The Foundation has funded $100 million in research to date.

SOURCE Michael J. Fox Foundation
Copyright©2007 PR Newswire.
All rights reserved

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