Navigation Links
Michael J. Fox Foundation Commits Up to $5 Million to Help Advance Neurotrophic Factors 'From Promise to Reality' As Parkinson's Treatment
Date:9/23/2009

NEW YORK, Sept. 23 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation has committed up to $5 million for research to successfully translate neurotrophic factor advances from pre-clinical and early-phase clinical work into a practical, patient-relevant treatment for Parkinson's disease. The funding will be awarded under a new Directed LEAPS (Linked Efforts to Accelerate Parkinson's Solutions) initiative.

The Foundation's intention is to identify and drive ambitious projects with a clear plan for accelerating trophic factor therapy through the stages of preclinical and clinical development up to and including Phase 2 clinical studies. Also of interest are therapeutic approaches that include evidence that the trophic factor being studied holds potential for neuroregeneration (helping the brain rejuvenate sick cells) and not merely neuroprotection (protecting existing neurons from death).

Neurotrophic factors (also known as trophic factors or growth factors) are specialized proteins that protect and nourish neurons in the brain, including the dopamine neurons that die in Parkinson's disease. They are a high-priority therapeutic target for MJFF, which has committed approximately $20 million to their development to date, because they have shown potential to slow or stop the progression of Parkinson's in the brain -- something no currently available treatment has been proven to do.

In the last several years, preclinical studies and several early-phase clinical trials in neurotrophic factors have shown promise to revolutionize the treatment of PD. Research increasingly indicates that trophics are safe for use in people, and several Phase 1 neurotrophic clinical trials have shown signs of efficacy. But results from all previous trials have been ultimately inconclusive, and no trophic-based approach has yet been demonstrated to be both safe and efficacious in a Phase 2 clinica
'/>"/>

SOURCE Michael J. Fox Foundation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Michael Moores SiCKO Becomes the Third Highest Grossing Documentary of All Time Surpassing An Inconvenient Truth
2. Katie Hood Appointed Interim Chief Executive Officer of Michael J. Fox Foundation
3. Clarient Names Michael J. Pellini, M.D. Chief Operating Officer
4. Digital Healthcare Announces Dr. Michael Fleming Joins Executive Team as Medical Director
5. Michael J. Fox Foundation Commits Up to $2 Million for PD Drug Development Under Target Validation 2008
6. BioElectronics Corporation Announces Addition of Michael Seidenman, R.Ph. as Vice President of Sales
7. BioSeek Appoints Michael C. Venuti, Ph.D., Chief Executive Officer
8. Irene Hegeman Richard, MD, Appointed Senior Medical Advisor to The Michael J. Fox Foundation
9. Actress Jenifer Lewis, Authors Dr. Michael Eric Dyson and Susan Taylor Among Featured Speakers for Senator Hughes Behavioral Mental Health Summit
10. Michael J. Fox Foundation Launches Rapid Response Innovation Awards 2008 Following Strong Inaugural Year Response
11. Siemens Medical Solutions Michael Long Recognized as one of Computerworlds 2008 Premier 100 IT Leaders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... (HealthDay News) -- A group representing U.S. obstetricians is ... shot. According to the American College of Obstetricians ... have upheld the safety and effectiveness of flu vaccination ... and can be particularly dangerous to pregnant women, as ... Dr. Laura Riley, chair of the college,s Immunization Expert ...
(Date:8/20/2014)... By Dennis Thompson ... -- A new experimental drug has saved a group of ... of Ebola virus that kills up to 90 percent of ... monkeys infected with lethal doses of Marburg virus, even when ... study published Aug. 20 in the journal Science Translational ...
(Date:8/20/2014)... than 42 percent of women underwent breast reconstruction ... associated with foregoing reconstruction included being black, having ... Author: Monica Morrow, M.D., of the Memorial Sloan ... Background: The Women,s Health and Cancer Rights Act ... following a mastectomy. Still, most women who undergo ...
(Date:8/20/2014)... imaging study of chronic users of codeine-containing cough ... of brain white matter and associates these changes ... Researchers used diffusuion tensor imaging (DTI) (an MR ... the white matter integrity of chronic CCS users. ... brain, including the inferior fronto-occipital fasciculus, which other ...
(Date:8/20/2014)... Hundreds of Mirena IUD lawsuits ( ... were allegedly injured due to spontaneous migration of the ... County Superior Court, Bernstein Liebhard LLP reports. According to ... the Court has established procedures regarding the production of ... part of the proceeding’s initial disposition pool. (In Re: ...
Breaking Medicine News(10 mins):Health News:All Pregnant Women Need Flu Shot: Ob/Gyn Group 2Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 2Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 3Health News:Patient perspectives on breast reconstruction following mastectomy 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 3Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 4
... , , NORTHBROOK, Ill., ... drinking water quality and safety, announced today a new certification ... demonstrate compliance with new, stricter low lead requirements that will ... , California Assembly Bill 1953 (AB 1953), now a state ...
... , , RIO DE JANEIRO, Dec. 21 Amilpar (Bovespa: ... largest managed care organization in Brazil, in accordance with article ... CVM Instruction nº 358/02, and in addition to the Relevant ... 9, 2009, informs its shareholders and the market that its ...
... A ... find out who has the most compelling dental story. The winner will be determined by an ... ... Austin, Texas cosmetic dentistry practice, is getting ready to let the world know who ...
... ... lift spirits. , ... 21, 2009 -- The Peachtree Evolution Series LED wall sconce takes the art of multi-colored ... design of any space. , , ,Choose a Vibrant and fast moving sequence for clubs, ...
... 20 More than 40 groups have joined together to ... "Virtual Vigil" starting at 9 pm tonight and wrapping after ... representing millions on the left, right, seniors, tea parties, doctors, ... Senate for laying a $200 billion windfall in mandatory premiums ...
... expert says , SUNDAY, Dec. 20 (HealthDay News) -- Think twice ... your holiday wish list. You may get it and find out ... you thought you would, a new study suggests. , That,s because ... to our expectations. The cappuccino machine is a hassle to clean, ...
Cached Medicine News:Health News:Underwriters Laboratories Announces Alternative Certification Program for Lead Free Verification of Cooking and Plumbing Products 2Health News:10 Days Left to Win $15,000 in Dental Work for Most Interesting Patient in the World Contest at Austin Cosmetic Dentistry Practice 2Health News:Add Drama and Lift Spirits While Significantly Reducing Energy Cost; Peachtree Introduces the Evolution Series, LED, Energy Efficient Wall Sconce 2Health News:Left/Right Healthcare 'Virtual Vigil' Tonight at 9 PM Until Senate Votes; Broad Coalition Says Punishes Some States, Windfall for Insurance Companies 2Health News:Be Careful What You Wish For This Holiday Season 2
(Date:8/20/2014)... YORK , Aug. 20, 2014 /PRNewswire/ ... research report is available in its catalogue: ... Market for Bluetooth, RFID, Zigbee, UWB WWAN, ... http://www.reportlinker.com/p0652514/Wireless-Opportunities-in-Healthcare-The-Market-for-Bluetooth-RFID-Zigbee-UWB-WWAN-WMAN-WLAN-and-other-technologies.html Kalorama ... for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, ...
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com ... available in its catalogue: Global Coatings ... http://www.reportlinker.com/p01375204/Global-Coatings-for-Medical-Devices-Industry.html This report analyzes ... in US$ Million by the following Product Segments: ... Coatings. The report provides separate comprehensive analytics for ...
(Date:8/20/2014)... -- Amerigen Pharmaceuticals Ltd. announces that its Chinese subsidiary, ... FDA (CFDA) approval and has subsequently launched its ... China domestic market.  Under the ... Sinochem Jiangsu Pharmaceutical Co., Ltd., Amerigen is manufacturing ... China CFDA certified oral solid dose facility in ...
Breaking Medicine Technology:Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 2Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 3Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 4Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 5Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 6Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 7Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 8Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 9Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 10Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 11Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 12Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 13Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 14Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 15Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 16Global Coatings for Medical Devices Industry 2Global Coatings for Medical Devices Industry 3Global Coatings for Medical Devices Industry 4Global Coatings for Medical Devices Industry 5Global Coatings for Medical Devices Industry 6Global Coatings for Medical Devices Industry 7Global Coatings for Medical Devices Industry 8Global Coatings for Medical Devices Industry 9Global Coatings for Medical Devices Industry 10Global Coatings for Medical Devices Industry 11Global Coatings for Medical Devices Industry 12Global Coatings for Medical Devices Industry 13Global Coatings for Medical Devices Industry 14Global Coatings for Medical Devices Industry 15Global Coatings for Medical Devices Industry 16Global Coatings for Medical Devices Industry 17Global Coatings for Medical Devices Industry 18Global Coatings for Medical Devices Industry 19Global Coatings for Medical Devices Industry 20Global Coatings for Medical Devices Industry 21
... its primary endpoint of non-inferiority to a rapid-acting ... ... MannKind,Corporation (Nasdaq: MNKD ) today released preliminary top-line results from,a ... type 1 diabetes (Study 009). This study compared the safety and,efficacy ...
... updated since ASCO, show time without tumor growth now reaches ... patients in trial remained progression-free beyond ten ... months of treatment,- RAD001 is first drug to show significant benefit after failure of initial,therapy, Sutent(R) ... ...
Cached Medicine Technology:MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes 2MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes 3MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes 4MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes 5Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer 2Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer 3Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer 4Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer 5Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer 6
... the world's first directly illuminated, hand-held ... tradition of bringing superior ophthalmic technology ... keeping with that tradition, Welch Allyn ... Ophthalmoscope. With its newly designed precision ...
... The TOPCON 3D+ ALE-3700/3700PC/3700CF patternless processing system ... frame, quickly, accurately and with the convenience ... the 3D+ FR-20 Frame Reader, advanced processing ... is available with a polycarbonate feature (ALE-3700 ...
Inquire...
... Model II, is very simple to use ... obtained because it is only necessary to ... with internal reading scales then indicating the ... Since displacements between the centers of spectacle ...
Medicine Products: