Navigation Links
Michael J. Fox Foundation Awards $2.8 Million to Drive Development of Parkinson's Disease Biomarker Pipeline
Date:2/4/2010

The development of drug biomarkers is also critical to provide researchers with a tool for conclusively assessing whether a given drug is reaching brain areas of interest and/or achieving its desired effect. Danna Jennings, MD, of the Institute for Neurodegenerative Disorders is working with a brain imaging molecule that can be used as a biomarker for drugs targeting a glutamate receptor in the brain known as mGluR5. Drugs that block mGluR5 (antagonists) have been shown in pre-clinical models to reduce dyskinesias, the involuntary movements that are a debilitating side effect of dopamine replacement therapy to treat PD. Dr. Jennings will use the imaging molecule to confirm that a clinically approved mGluR5 antagonist is reaching the brain at appropriate levels and to determine the most effective dose of the drug for use in future PD clinical trials.

The following is a complete list of funded projects, which are made possible through the generous support of The Brin Wojcicki Foundation. Grant abstracts and researcher bios are available on the Foundation's Web site, www.michaeljfox.org.

T-Cell Receptor Changes as a Biomarker of Parkinson's Disease

Chuanhai Cao, PhD, University of South Florida, College of Medicine

Analysis of the Enteric Nervous System Using Routine Colonoscopy Biopsies: a Biomarker of Neurodegeneration in Parkinson's Disease?

Pascal Derkinderen, MD, PhD, Department of Neurology, Inserm U913, Nantes, France

QE3 Trial Ancillary Biomarkers Study

'/>"/>

SOURCE Michael J. Fox Foundation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Aleres Dr. Michael Taitel Presents Compelling Evidence at IBI/NBCH Health & Productivity Forum that Wellness Programs Positively Impact Health & Productivity
2. Michael Jackson Propofol Expert, Barry Friedberg MD, Spoke at Pan Pacific Surgery Meeting
3. TV Wellness Expert Jillian Michaels Teams With Harley-Davidson to Help Women Channel Their Inner Drive and Live More Fulfilling Lives
4. Michael J. Fox Foundation Awards $2 Million for Clinical Research on Postural Instability and Gait Disturbances in Parkinsons Disease
5. Michael J. Fox Foundation Awards $1 Million for Critical Step Toward Development of Dyskinesia Treatments
6. Rush Limbaugh & Michael Steele Join Tea Party Support & Social Security Institute-Demand GOP Senate Stop ObamaCare by Any Means Possible
7. Dr. Michael Aziz Releases a New Nutrition Book That Debunks Most Popular Diets and Diet Books
8. BIDMC scientists awarded grants from Michael J. Fox Foundation for Parkinsons research
9. Michael S. Burg Appointed as Co-Lead Counsel in the Yasmin/Yaz Multidistrict Litigation
10. Syracuse Attorney Michael P. Kenny Prepares Suit Against Sony Due to Client's Seizure Caused By Video Game
11. Majesco Entertainment and Interactive Game Group Release Jillian Michaels Fitness Ultimatum 2010 For Nintendo DS(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... Philadelphia, Pa. (April 24, 2014) - Contact lenses coated with ... contact lens-related infections, reports a study in Optometry ... American Academy of Optometry . The journal is published ... Wolters Kluwer Health . , Studies in animals and ... with the antimicrobial peptide melimine, according to the new research ...
(Date:4/24/2014)... be boring and irrelevant, could offer an alternative to ... Dr Milena Furtado, and her team from the Australian ... heart cell fibroblast is a close relative to a ... , In research published today in Circulation Research ... unique cells due to their genetic program, and will ...
(Date:4/24/2014)... in the world to discover a gene mutation in ... Ameloblastoma is an odontogenic tumour with a high tendency ... in the posterior of the lower jaw. Ameoloblastomas are ... the jaws as well as loss of several teeth. ... surgery and the recurrence of ameloblastoma, but finding such ...
(Date:4/24/2014)... by a scientist at the University of York reveals ... the development of the nervous system may also play ... A research team, led by Dr Will Brackenbury, ... Biology at York, has studied how voltage-gated sodium channels ... are found in the membranes of excitable cells, such ...
(Date:4/23/2014)... Spokane have developed a new way to detect ... the wheel. , Their recently patented technology is ... in drowsy driversand offers an affordable and more ... detection systems. , Van Dongen"Video-based systems that use ... out of its lane are cumbersome and expensive," ...
Breaking Medicine News(10 mins):Health News:Study supports safety of antimicrobial peptide-coated contact lenses 2Health News:Study supports safety of antimicrobial peptide-coated contact lenses 3Health News:Boring cells could hold the key to heart disease 2Health News:Breast cancer replicates brain development process 2Health News:WSU innovation improves drowsy driver detection 2
... MYL ),announced today the appointment of Daniel ... as a member of the company,s senior leadership ... Crookshank is,responsible for all investment community communication as ... that proactively promote Mylan to,the investment community., ...
... Ala., July 21 Health,Care Systems, Inc. (HCS), ... market leader in medication reconciliation solutions, has entered,into ... the largest,locally owned not-for-profit hospitals in the nation ... as a teaching facility for The,University of Alabama ...
... the Internet, calls for action from ICANN, US-based domain ... ... 21 LegitScript.com, an,online pharmacy verification service, and KnujOn.com, an Internet ... engaged in the illicit sale of anabolic steroids., Steroid abuse ...
... future alternative to bypass surgery, researchers say , , FRIDAY, ... grown in mice the kind of functioning heart blood ... One ultimate goal is to replace some heart surgery ... in the body, providing a system of blood vessels ...
... more likely to be iron-deficient, study finds , , FRIDAY, ... breast-fed for the first six months of life are ... likely to be deficient in iron, and therefore at ... at 154 mothers and their babies in Guadalajara, Mexico. ...
... July 18 (HealthDay News) -- Correcting lazy eye in adults ... been able to do that -- at least partially and ... Someone with lazy eye -- ophthalmologists call it amblyopia -- ... other. Early treatment often has a child wearing a patch ...
Cached Medicine News:Health News:Daniel E. Crookshank Joins Mylan as Vice President - Investor Relations 2Health News:Huntsville Hospital Signs With Health Care Systems, Inc. for Automated Medication Reconciliation Services 2Health News:Kids at Risk: Report Identifies 150 Websites Selling Anabolic Steroids 2Health News:Heart Blood Vessels Grown in the Lab 2Health News:Breast-Fed Babies Have Fewer GI Infections 2Health News:Magnetic Pulses to Brain Improve Lazy Eye in Adults 2Health News:Magnetic Pulses to Brain Improve Lazy Eye in Adults 3
(Date:1/15/2014)... RAPIDS, Mich. , Jan. 15, 2014 As health ... the flu virus, select Meijer pharmacies in Michigan ... strep throat to eligible patients, enabling Meijer pharmacists to administer ... strict protocol set by a physician participating in the study. ...
(Date:1/15/2014)... , January 15, 2014 Shire plc (LSE: SHP, ... Office of Fair Trading (OFT) approval condition to the announced tender ... VPHM).   As a result of the waiver, the ... to complete the tender offer on January 24, 2014 following the ...
(Date:1/15/2014)... 15, 2014 Tegra Medical is very pleased to announce ... its new Chief Executive Officer.  Mark was promoted from his ... overseen the company,s four facilities in Massachusetts ... King joined Tegra Medical in 2012 with 20+ years of ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3
... , CAMBRIDGE, Mass., Oct. 14 Northern Light ( ... EBSCO Publishing (EBSCO) ( www.ebscohost.com ) that ... than 4,000 bio-pharmaceutical, health sciences and general business magazines, ... strategic research portals. SinglePoint users who also subscribe ...
... Luminous Medical, Inc. announced today that it has ... for exclusive rights to incorporate its glucose sensor into ... its monitor to enable clinicians to control hyperglycemia in ... was planning to use a sensing technology based on ...
Cached Medicine Technology:Northern Light Adds 4,000 Bio-Pharma, Health Sciences and General Business News and Journal Sources from EBSCO Publishing 2Northern Light Adds 4,000 Bio-Pharma, Health Sciences and General Business News and Journal Sources from EBSCO Publishing 3Luminous Medical, Inc. Secures Exclusive Rights to Glucose Sensor for Its Automated Glucose Monitor 2
The Precedent establishes a new generation of revision hip stems....
Calcar replacement stems provide options for revision and trochanteric fractures. Revision hip surgery and trauma often require prosthetic designs that replace proximal medial calcar bone loss....
...
...
Medicine Products: