Navigation Links
Michael J. Fox Foundation Awards $2.8 Million to Drive Development of Parkinson's Disease Biomarker Pipeline
Date:2/4/2010

The development of drug biomarkers is also critical to provide researchers with a tool for conclusively assessing whether a given drug is reaching brain areas of interest and/or achieving its desired effect. Danna Jennings, MD, of the Institute for Neurodegenerative Disorders is working with a brain imaging molecule that can be used as a biomarker for drugs targeting a glutamate receptor in the brain known as mGluR5. Drugs that block mGluR5 (antagonists) have been shown in pre-clinical models to reduce dyskinesias, the involuntary movements that are a debilitating side effect of dopamine replacement therapy to treat PD. Dr. Jennings will use the imaging molecule to confirm that a clinically approved mGluR5 antagonist is reaching the brain at appropriate levels and to determine the most effective dose of the drug for use in future PD clinical trials.

The following is a complete list of funded projects, which are made possible through the generous support of The Brin Wojcicki Foundation. Grant abstracts and researcher bios are available on the Foundation's Web site, www.michaeljfox.org.

T-Cell Receptor Changes as a Biomarker of Parkinson's Disease

Chuanhai Cao, PhD, University of South Florida, College of Medicine

Analysis of the Enteric Nervous System Using Routine Colonoscopy Biopsies: a Biomarker of Neurodegeneration in Parkinson's Disease?

Pascal Derkinderen, MD, PhD, Department of Neurology, Inserm U913, Nantes, France

QE3 Trial Ancillary Biomarkers Study

'/>"/>

SOURCE Michael J. Fox Foundation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Aleres Dr. Michael Taitel Presents Compelling Evidence at IBI/NBCH Health & Productivity Forum that Wellness Programs Positively Impact Health & Productivity
2. Michael Jackson Propofol Expert, Barry Friedberg MD, Spoke at Pan Pacific Surgery Meeting
3. TV Wellness Expert Jillian Michaels Teams With Harley-Davidson to Help Women Channel Their Inner Drive and Live More Fulfilling Lives
4. Michael J. Fox Foundation Awards $2 Million for Clinical Research on Postural Instability and Gait Disturbances in Parkinsons Disease
5. Michael J. Fox Foundation Awards $1 Million for Critical Step Toward Development of Dyskinesia Treatments
6. Rush Limbaugh & Michael Steele Join Tea Party Support & Social Security Institute-Demand GOP Senate Stop ObamaCare by Any Means Possible
7. Dr. Michael Aziz Releases a New Nutrition Book That Debunks Most Popular Diets and Diet Books
8. BIDMC scientists awarded grants from Michael J. Fox Foundation for Parkinsons research
9. Michael S. Burg Appointed as Co-Lead Counsel in the Yasmin/Yaz Multidistrict Litigation
10. Syracuse Attorney Michael P. Kenny Prepares Suit Against Sony Due to Client's Seizure Caused By Video Game
11. Majesco Entertainment and Interactive Game Group Release Jillian Michaels Fitness Ultimatum 2010 For Nintendo DS(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Montrose, Colorado (PRWEB) December 20, 2014 It’s ... many, travel is something that is put to the wayside ... those who still have that travel “itch” and that burning ... Inn Montrose accommodates families on their journey to Telluride with ... trip, get visitors to and from the resort, and ensure ...
(Date:12/19/2014)... December 19, 2014 Energy Textiles ... are now available. Celliant, the world’s leading responsive ... and pillowcases. , There are a number of ... circulation, increased oxygenation and balanced body temperature; which ... and pain relief; enhanced athletic performance; and overall ...
(Date:12/19/2014)... 2014 SuperCloset raises the bar once ... continues to offer indoor growers the most efficient and ... new SuperClone Rooms with the award winning SuperRooms ... hydroponic grow room setup. , The SuperClone Room features ... SuperCloner 50 . The SuperClone Room ...
(Date:12/19/2014)... 20, 2014 An evening dress is perfect ... lady’s closet. Discount-Dress.com, a distinguished dresses retailer, has unveiled its ... dresses in this great shopping platform. Customers can ... staff's hard work, Discount-Dress.com has been accepted and praised by ... and easier shopping stage for clients. In order to expand ...
(Date:12/19/2014)... (HealthDay News) -- New research warns parents that buying an older ... Nearly half of teen drivers killed in the United States ... 11 years old and often lacked important safety features that are ... teen drivers killed in crashes were in cars at least six ... old, 31 percent were in cars 11 to 15 years old, ...
Breaking Medicine News(10 mins):Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2Health News:Attractive Evening Dresses Announced by Discount-Dress.com 2Health News:Older Cars a Bad Choice for Younger Drivers 2
... who are diagnosed with bone cancer could benefit from better ... University of Nottingham. The Bone Cancer Research Trust launches ... project at the University which is testing a theory that ... Researchers at the School of Clinical Sciences, Division of ...
... Reporter , MONDAY, Oct. 11 (HealthDay News) -- The ... involving human embryonic stem cells has been injected with ... patient, being cared for at the Shepherd Center in ... The center specializes in treating these types of injuries. ...
... last six months of life has become progressively more expensive ... the United States and older adults in Canada, with a ... life in both countries, according to two reports posted online ... issue of Archives of Internal Medicine , one of ...
... intravitreous (into the eye) injection of a chemotherapy drug ... against the eye diseasedo not appear to be associated ... when compared with existing therapies, according to a report ... , one of the JAMA/Archives journals. "More than ...
... Oct. 11 (HealthDay News) -- Women with epilepsy may be at ... The study included 375 women who planned to have a ... or for up to 10 years. During the study period, 62 ... among women with epilepsy was more than twice the 15 percent ...
... of a computer or television screen are more likely to ... The PEACH project, a study of over a 1,000 ... spent in front of a screen as well as their ... children,s sedentary time and moderate physical activity. The results ...
Cached Medicine News:Health News:Hope for a new treatment for bone cancer 2Health News:First Patient Treated in U.S.-Approved Embryonic Stem Cell Trial 2Health News:First Patient Treated in U.S.-Approved Embryonic Stem Cell Trial 3Health News:End-of-life care patterns shift for patients with heart failure in both US and Canada 2Health News:End-of-life care patterns shift for patients with heart failure in both US and Canada 3Health News:End-of-life care patterns shift for patients with heart failure in both US and Canada 4Health News:End-of-life care patterns shift for patients with heart failure in both US and Canada 5Health News:Certain new therapies for age-related eye disease do not appear to increase heart risks 2Health News:Study Sees Link Between Epilepsy, Infertility 2Health News:Screen time linked to psychological problems in children 2
(Date:12/19/2014)... -- RESMED INC. (NYSE: RMD ) today announced that ... results on Thursday, January 22, 2015, after the New York ... will be issued after 1:00 p.m. US Pacific Time and ... and future outlook. The earnings call is scheduled ... live webcast of the call can be accessed on ResMed,s ...
(Date:12/19/2014)... , Dec. 18, 2014 Since last ... the site now known as the leading online black ... seen explosive growth in its offering of drugs and ... Alliance show the takedowns did succeed in lowering the ... last review of the markets in August. But some ...
(Date:12/19/2014)... LYON, France , Dec. 19, 2014 ... ) and Adocia (Euronext Paris: FR0011184241 – ADOC) today ... ultra-rapid insulin, known as BioChaperone Lispro, for treatment in ... Lispro relies on Adocia,s proprietary BioChaperone® technology and is ... Adocia will develop BioChaperone Lispro with the goal of ...
Breaking Medicine Technology:ResMed To Announce Second Quarter 2015 Results 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3
... Inc. (Nasdaq: STXS ) today announced that executive ... Conference on Tuesday, September 28, 2010 at 8:30 a.m. ET ... an overview of the Company,s business strategy and recent corporate ... invitation only. A live audio and slides webcast of Stereotaxis, ...
... BEDFORD, Mass., Sept. 23 Instrumentation Laboratory (IL), today announced ... on Wednesday, October 13, 2010 at the Grand Hyatt Nusa ... am to 12:00 pm, local time.  The forum will focus ... hemostasis.  All healthcare professionals, practicing in the Asia Pacific region ...
Cached Medicine Technology:Stereotaxis to Present at the JMP Securities Healthcare Conference 2Stereotaxis to Present at the JMP Securities Healthcare Conference 3Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 2Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 3Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum 4
The ultimate combination of comfort, convenience and affordability, recommended for daily wear, also approved for extended wear (1-7 days)....
SofLens Multi-Focal with unique Natra-Sight Optics designed to provide broad transition for near, intermediate and far vision, SofLens Multi-Focal lenses offer crisp, clear vision at all distances....
... With the Hertel, the unit ... and held firmly against the ... with the center of the ... the two temporal orbital walls, ...
Fastest, easiest and least expensive method for measuring exophthalmos. By sighting at right angles, this device eliminates parallax and allows the clinician to measure the amount of protrusion or bu...
Medicine Products: