Navigation Links
Mice Exposed to Smoke Helped by Blood Pressure Drug: Study
Date:1/6/2012

FRIDAY, Jan. 6 (HealthDay News) -- The blood pressure medicine losartan [Cozaar] helped prevent lung damage in mice that were exposed to cigarette smoke for two months, researchers say.

Specifically, the drug prevented lung tissue breakdown, airway wall thickening, inflammation and lung overexpansion in the animals, according to the Johns Hopkins researchers.

The findings have led to a clinical trial of losartan in people with smoking-related chronic obstructive pulmonary disease (COPD). About 12 million Americans have COPD, which is the third leading cause of death in the United States.

The study, published in the Jan. 3 issue of the Journal of Clinical Investigation, was funded by drugmaker Merck & Co. and the U.S. National Heart, Lung and Blood Institute.

"The results of our study in mice suggest that losartan or similar drugs could serve as an effective treatment for smoking-related lung diseases in humans," senior investigator Dr. Enid Neptune, a pulmonologist and assistant professor at the Johns Hopkins University School of Medicine, said in a Hopkins news release.

"And because these drugs are already approved for use in the United States as safe and effective treatments for hypertension, incorporating them into our treatment regimen for COPD would be quite rapid," Neptune added.

"It is very exciting that an existing medication has proven capable in an animal model of not only treating the problems of COPD, but also disrupting the biological pathway that precipitated them," pulmonologist Dr. Robert A. Wise, a Johns Hopkins professor who is leading the human clinical studies, said in the news release.

"If our tests in people prove successful, we could help restore lung health to millions of people who have suffered from tobacco addiction," Wise added.

Existing therapies for smoking-related COPD mainly provide relief of symptoms, such as shortness of breath, coughing and mucus
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. WTC workers exposed earlier to dust cloud have higher risk of atherosclerotic lesions
2. Parkinsons disease risk greater in those exposed to trichloroethylene
3. Women exposed to diethylstilbestrol in the womb face increased cancer risk
4. Health Woes Still Strike Women Exposed to Banned Pregnancy Drug
5. Preterm infants exposed to stressors in NICU display reduced brain size
6. World Trade Center-exposed NYC firefighters face increased cancer risk
7. 17 percent of cancer nurses unintentionally exposed to chemotherapy, U-M study finds
8. Women Exposed to Combat Trauma as Resilient as Men: Study
9. High risk of Parkinsons disease for people exposed to pesticides near workplace
10. Adalimumab levels detected in cord blood and infants exposed in utero
11. Pet Dogs May Be Exposed to High Levels of Flame Retardants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mice Exposed to Smoke Helped by Blood Pressure Drug: Study
(Date:4/27/2015)... April 27, 2015 The Mount Sinai ... seamless referral process for the Health System’s care providers. ... failure or diabetes, for instance, may have more than ... coordinate with many other care providers. With medical practices ... thousands of patients each year, the need for an ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 Healthpointe clinics ... treatments for nail fungi and infections. Onychomycosis, which is ... up to 10% of adults in the Western population. ... irregularity in thickness. , Healthpointe’s Anaheim clinic ... a branch dedicated to providing quality skincare products and ...
(Date:4/27/2015)... The Global Pharmaceutical Packaging Market 2015 – ... 5.9% during the period 2015 – 2019. Plastics will ... packaging market, mainly due to their cost effectiveness and ... is extremely fragmented with the presence of several global ... market with the rest being occupied by several international ...
(Date:4/27/2015)... Texas has saved $433 million by converting ... providing drug offenders with addiction treatment, according to an ... Several states, including Massachusetts, are considering adopting justice reinvestment ... formed community recovery programs to help redress rampant addiction ... State Governments WA, ID, NE, KS, MI, PA, ...
(Date:4/27/2015)... Los Angeles gummy smile doctor , ... treatments. “Some people have too much gum tissue and ... purely cosmetic issue that can happen to anyone.” Gummy ... more of the natural tooth structure for a more ... the underlying bone and create a more harmonious facial ...
Breaking Medicine News(10 mins):Health News:Mount Sinai Launches System for Faster Referrals 2Health News:Mount Sinai Launches System for Faster Referrals 3Health News:Southern California Healthpointe Clinics Now Treating Nail Fungus 2Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 2Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 3Health News:Global Pharmaceutical Packaging Market to Grow at 5% CAGR to 2019 Says a New Report at RnRMarketResearch.com 4Health News:Texas Saves $443 Million Embracing Justice Reinvestment for Drug Charges 2Health News:Texas Saves $443 Million Embracing Justice Reinvestment for Drug Charges 3Health News:Los Angeles Periodontist, Dr. Sharyar Baradaran, Now Offers Comprehensive Treatments to Correct Gummy Smiles 2
... March 27 Otsuka American,Pharmaceutical Inc., the U.S. ... has agreed to pay more than,$4 million to ... drug, for "off-label" uses, the Justice Department announced,today., ... entered into an agreement,with Bristol-Myers Squibb (BMS) to ...
... infections , , THURSDAY, March 27 (HealthDay News) -- ... been determined by biologists at Purdue University in Indiana. ... infects more than 50 million people a year and ... is prevalent in Southeast Asia, Central America and South ...
... lab would carry therapeutic cells to their destination in ... A "mini stem cell lab" created by U.S. researchers ... biological applications, as well as in the design of ... The team at the Institute for BioNanotechnology in Medicine ...
... Electronics Ltd.,(NYSE: TEL ; BSX: TEL) today presented ... support the construction of a new Fisher House(TM) at,Womack ... senior,vice president of Tyco Electronics and head of the ... Electronics,materials manager associate who just returned from a one-year ...
... WASHINGTON, March 27 The Men,s Health Policy,Center, ... Health Network,(MHN), announced today that they are hosting ... for Medicare and Medicaid Services (CMS) practice,that unfairly ... "This petition allows people who are impacted ...
... American women, SAN DIEGO, March 27 How ... Clinton despite the physical and emotional strain she,s,experienced on ... Clinton, who is making a historic presidential bid. Her ... recently posed,similar questions to its members in a study, ...
Cached Medicine News:Health News:Otsuka to Pay More Than $4 Million to Resolve Off-Label Marketing Allegations Involving Abilify 2Health News:Biologists Discover How Dengue Virus Matures 2Health News:Researchers Create Protective Sac for Growing Stem Cells 2Health News:Tyco Electronics Contributes $25,000 Towards Construction of New Fisher House(TM) at Ft. Bragg 2Health News:Men's Health Policy Center Hosts Petition to Protest Government Barrier to Prostate Cancer Medications 2Health News:What Drives Hillary to Get Up Every Morning and Hit the Campaign Trail? 2
(Date:4/24/2015)... 24, 2015  Bayer Corporation hosted its annual "Take Your ... Bayer HealthCare US headquarters.  This is Bayer,s second "Take Your ... Whippany campus, and Thursday,s event welcomed 230 children ... at work. Fortunately, for the kids, this was ... whose mission is "Science For A Better Life," Bayer made ...
(Date:4/24/2015)... , April 24, 2015 In today,s ... employee groups around the world to access diverse ... hours. While there are many areas to misstep ... examine which best practices are necessary and beneficial ... According to research by benchmarking firm, ...
(Date:4/24/2015)... and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ) has announced ... report to their offering. The analysts ... CAGR of 7.07% over the period 2014-2019 ... segments: Equipment and Consumables. This report covers the present ... market for the period 2015-2019. ...
Breaking Medicine Technology:Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4Work Around the Clock: Building Effective Global Capabilities 2Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2
... May 2, 2011 NewCardio, Inc., (OTC BB: NWCI) a ... prestigious NYC Bright Lights Conference at the Le Parker Meridien ... of its kind with an exclusive focus on publicly traded ... will present on May 10, 2011 at 9 a.m. ET. ...
... Fla., May 2, 2011 The Unilens Vision Inc. ... of Directors today declared a quarterly cash dividend of $0.045 per ... record at the close of business on May 13, 2011. ... Specialty Contact Lens Company" Established in 1989, Unilens ...
Cached Medicine Technology:NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 2NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 3NewCardio to Showcase Cardiac Diagnostic Technology at MDB Capital's Bright Lights Conference in New York City on May 10, 2011 4Unilens Vision Inc. Declares Quarterly Cash Dividend of $0.045 Per Share 2
Lightweight Pneumatic Conserver., ,NOTE: All models passed the ASTM PS 127-00 regulator ignition safety test....
Lightweight Pneumatic Conserver., ,NOTE: All models passed the ASTM PS 127-00 regulator ignition safety test....
... ,Offers an average 5:1 increase in usage ... use of a standard cannula. , ,The ... offers ambulatory oxygen patients a superior alternative to ... 2-year warranty. , ...
Redesigning the World's Oxygen Therapy One Device at a Time. , ,Everything you like about our OXYMATIC 400 Series conservers, only better!...
Medicine Products: