Navigation Links
Metlife Foundation recognizes Emory Alzheimer's disease researcher
Date:5/15/2014

Lary C. Walker, PhD, research professor of neuropharmacology and neurologic diseases and associate professor of neurology, Yerkes National Primate Research Center, Emory University, is a recipient of the 2014 MetLife Foundation Awards for Medical Research. The winners were recognized at a scientific briefing and awards ceremony today in New York.

Walker was recognized with his Germany-based colleague Mathias Jucker, PhD, for pioneering a unifying principle for the onset and evolution of late-life brain disorders, such as Alzheimer's and Parkinson's diseases, based on similarities with rare, fatal disorders known as prion diseases. Jucker is full professor at the Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases in Tbingen, Germany.

Together, Walker and Jucker have amassed compelling experimental evidence that small aggregates of the basic proteins in prion diseases act as seeds that start a domino-like chain reaction that causes similar proteins to aggregate and spread the disease throughout the brain. They have jointly published a number of seminal papers on the seeding concept in age-related brain diseases, beginning with a study in Science in 2006, and their work has decisively established the seeding model as a comprehensive mechanistic explanation for the abnormal assembly of proteins and their spread through the brain in many of the devastating, untreatable brain diseases that affect humans.

Examples of their accomplishments include finding: protein-rich seeds of aggregated amyloid-beta (Aβ) underlie both the emergence and progression of Aβ abnormalities in the brains of animals; variations in the size and molecular structure of these seeds profoundly influence their disease-causing characteristics; and small, soluble collections of Aβ are especially potent seeds and are key targets for therapeutic intervention and possibly also early biomarkers of Alzheimer's disease in bodily fluids.

"I am thrilled to receive this award, which has honored so many pioneering Alzheimer's researchers during the past quarter century," says Walker. "I am indebted to the many colleagues and students who have made my research possible, and to the Yerkes National Primate Research Center and Emory University for their continuing support."

According to recent estimates, without the development of treatments that either delay Alzheimer's disease onset or slow its progression, by 2050 more than 100 million people worldwide will be living with Alzheimer's disease. The time spent caring for people with Alzheimer's disease will be measured in billions of hours, and the cost will be trillions of dollars.

At the heart of the MetLife awards is a belief that research is the road to understanding and ultimately treating Alzheimer's disease. Walker's award comes with a $100,000 institutional grant, which he will use to further his research with his colleagues at Yerkes, Emory, Georgia Tech and the University of Tbingen to better understand how Alzheimer's disease progresses through the brain and why the disease affects people in different ways.

"We are proud of Dr. Walker and his many scientific achievements," says Stuart Zola, PhD, director of the Yerkes Research Center. "His research findings today are shaping the research of tomorrow, and the ultimate benefit will be improved health for our nation and the world."


'/>"/>

Contact: Lisa Newbern
lisa.newbern@emory.edu
404-727-7709
Emory Health Sciences
Source:Eurekalert

Related medicine news :

1. Two Leading Alzheimer's Disease Researchers Recognized with MetLife Foundation Awards
2. Kessler Foundation expert authors article on social enterprise business models
3. GW Cancer Institute receives $100,000 for patient navigator from the Avon Foundation
4. ASGE and ASGE Foundation hold Crystal Awards Dinner as part of Digestive Disease Week, May 4, in Chicago
5. Kessler Foundation scientist named 63rd Mendel Lecturer by St. Peters University
6. Kessler Foundation scientists receive Biogen Idec grant to study actual reality in MS
7. Kessler Foundation receives MS Research Center Award from National MS Society
8. The Brain & Behavior Research Foundation awards $4 million in NARSAD Grants
9. Interventional radiologists receive honors from SIR Foundation
10. Kessler Foundation MS scientist awarded Patterson Trust Award in Clinical Research
11. Kessler Foundation MS researchers study predictors of employment status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... As an industry leader, Eppendorf ... they will present the line of epMotion automated liquid handling system. This automated ... automate everyday pipetting tasks. , Ideal for scientists and lab technicians with no ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... planning services to communities in east Texas, is launching a regional charity effort ... , Founded in 1991, the Pediatric Brain Tumor Foundation (PBTF) has raised nearly ...
(Date:8/18/2017)... ... August 18, 2017 , ... The Golseth Agency, a Texas based ... area, is spearheading a regional charity campaign organized to provide support to Christina Upchurch ... of this year, Christina and her children returned from out of town to find ...
(Date:8/18/2017)... ... ... Alcovit, a lime-flavored beverage that rids the body of toxins linked to alcohol ... through Jet.com. , After 25 years of development, the company released its highly ... detox the body thereby avoiding alcohol-induced hangovers. Whether you’re having fun with friends or ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... “Dangerous Inheritance”: ... published author, Diane Winters. Diane is from Southwest Nebraska where she was raised ... friends and family. The story is fictional, but the friendships and mantra of ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... Bio-Ess Laboratories, LLC Chief Science Officer, Dr. Adam Elhofy , will ... Cell-Ess® Universal Titer Boost at the 9 th annual ... 21-25.  The Bioprocessing Summit convenes more than 1,000 international bioprocess professionals to ... ... Cell-Ess is the ...
(Date:8/15/2017)... FLINT, Mich. , Aug. 15, 2017 ... antidote naloxone to Michigan residents. ... Diplomat,s Flint retail pharmacy, G-3320 ... Naloxone, approved by the Food and Drug Administration, is ... drugs—including extreme drowsiness, slowed breathing, and loss of consciousness. ...
(Date:8/15/2017)... , Aug. 15, 2017 AccuGenomics, Inc., ... , today announced that the company has provided ... University of North Carolina at Chapel Hill and to ... designed to characterize and quantify HIV reservoir and viral ... pharmacological intervention. The HIV Cure Center is a joint ...
Breaking Medicine Technology: