Navigation Links
Method developed by VTT targets diagnosis of early Alzheimer's disease
Date:12/4/2012

A software tool called PredictAD developed by VTT Technical Research Centre of Finland promises to enable earlier diagnosis of the disease on the basis of patient measurements and large databases. Alzheimer's disease currently takes on average 20 months to diagnose in Europe. VTT has shown that the new method could allow as many as half of patients to get a diagnosis approximately a year earlier.

VTT has been studying whether patients suffering from memory problems could be diagnosed with Alzheimer's disease at an earlier stage in the light of their measurement values. The study involved processing patient measurements using VTT's PredictAD system, which was developed to support clinical decision-making. The findings were published in the Journal of Alzheimer's Disease in November 2012.

VTT has developed a novel approach for measuring the state of the patient reliably and objectively in cooperation with clinicians of University of Eastern Finland and Copenhagen University Hospital Rigshospitalet. The system compares the patient's measurements with measurements of other patients in large databases and provides an index and a graphical representation reflecting the state of the patient. Modern hospitals have huge data reserves that could be utilised in diagnostics by systematic mathematical modelling. Successful early diagnostics combined with new forms of care may reduce suffering and delay the institutionalisation of patients.

VTT's decision support system and imaging methods developed by VTT and Imperial College London were studied using ADNI material compiled in the United States. The study covered the records of a total of 288 patients suffering from memory problems, 140 of whom were diagnosed with Alzheimer's disease on average 21 months after the initial measurements.

The study showed that half of the patients could have been given a diagnosis of Alzheimer's disease around a year earlier. The accuracy of the predictions was comparable to clinical diagnosis. Treatments designed to slow down the progress of the disease could therefore be started earlier.

Early prediction of the disease is also important from the perspective of drug trials. If patients whose disease is still in the early stages can be included in trials, the treatment can be expected to be more effective.

The method will be tested at several memory clinics in Europe over the next few years. VTT's goal is to expand the method to also cover several other illnesses that cause dementia in addition to Alzheimer's disease.


'/>"/>

Contact: Jussi Mattila
jussi.mattila@vtt.fi
358-207-223-343
VTT Technical Research Centre of Finland
Source:Eurekalert

Related medicine news :

1. Nonsurgical Method to Measure Brain Pressure Shows Promise
2. New Method to Reveal Alzheimers Marker Shows Promise
3. New method to measure work addiction
4. Advanced genetic screening method may speed vaccine development
5. OHSU Oregon National Primate Research Center develops new, safer method for making vaccines
6. Hear to see: New method for the treatment of visual field defects
7. Safer Grilling Methods Might Cut Cancer Risk
8. Quick-Reversal Method May Be at Hand for New Blood Thinner
9. New delivery method improves efficacy of 2 common Parkinsons disease medications
10. Electronic data methods research seeks to build a learning health care system
11. New Stanford method enables sequencing of fetal genomes using only maternal blood sample
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... March 23, 2017 , ... Altec ... The Resource Group as their 2016 Microsoft Dynamics Partner of the Year at ... CA. The award recognizes The Resource Group for their outstanding relationship with ...
(Date:3/23/2017)... ... 23, 2017 , ... Sharon Kleyne, host of the nationally syndicated radio program, ... VoiceAmerica, recently talked on her program about how she is looking forward to World ... of an important distinction. World Water Day, Kleyne pointed out, is an occasion for ...
(Date:3/23/2017)... ... March 23, 2017 , ... It’s that time of year ... are thinking about summer internships , which can be frustrating when they don’t ... at Garden Media Group, a boutique public relations firm outside of Philadelphia, have offered ...
(Date:3/23/2017)... Richey, FL (PRWEB) , ... March 23, 2017 , ... ... announce that 2017 marks the 40th Anniversary of ABQAURP’s dedication to Health Care Quality ... honors those who have contributed not only to the association, but also to the ...
(Date:3/23/2017)... ... 23, 2017 , ... On 2 March 2017, the United ... Operations Command’s Patriot Award. The award was presented by the USSOCOM Commander, General ... for its significant and enduring support to the command. , Accepting the ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... March 23, 2017  Cornerstone Pharmaceuticals, Inc., ... major milestone today.  Following successful End-of-Phase I ... Food and Drug Administration (FDA), the Company ... regulatory path forward to conduct pivotal trials ... with acute myeloid leukemia (AML) and pancreatic ...
(Date:3/23/2017)... 2017 BioLineRx Ltd. (NASDAQ/TASE: BLRX), a ... that it has acquired Agalimmune Ltd., a private UK-based company ... a $6 million upfront payment, of which $3 million is ... payments may be made based on development and commercial milestones. ... Agalimmune,s ...
(Date:3/23/2017)... , March 23, 2017 AbbVie, a global ... Award-winning choreographer Julianne Hough is helping to ... in the Know about ME in EndoMEtriosis . " ... inspiring women to learn about and understand endometriosis, a ... and to address their symptoms with a healthcare ...
Breaking Medicine Technology: