Navigation Links
Methadone treatment suppresses testosterone in opioid addicts
Date:8/26/2014

HAMILTON, ON (Aug. 26, 2014) Treatment for opioid addiction tampers with the testosterone levels of male but not female opioid users, McMaster University research has shown.

In a paper published today by the journal Scientific Reports, the researchers say addiction treatment may need to change to address the side-effect.

The study found men using methadone, which is used for opioid addiction treatment, have significantly suppressed testosterone levels of about a quarter of the testosterone of men not using opioids. In women using methadone for addiction treatment, testosterone levels were not significantly impacted, even considering the menstrual cycle.

Low testosterone in men has been associated with poor quality of life as well as erectile dysfunction, fatigue, and mood disturbances.

"We expect that treating testosterone deficiency will improve outcomes of methadone treatment for patients, including treatment response and retention," said Dr. Zena Samaan, principal investigator of the study.

"Doctors should also ensure the patients are being prescribed the lowest dose of opioids including methadone for effective treatment to minimize testosterone suppression."

She added that this is a particular issue in Canada, the second largest consumer of opioids in the world.

Dr. Samaan is an associate professor of the psychiatry and behavioural neurosciences department of McMaster's Michael G. DeGroote School of Medicine.

The study involved information from 231 patients with opioid dependence receiving methadone in Ontario, as well as 783 Ontarians not using opioids. It was funded by the Drug Safety and Effectiveness Network of the Canadian Institutes of Health Research and the McMaster Department of Psychiatry and Behavioural Neurosciences. The study was conducted by the Population Genomics Program of McMaster's Chanchlani Research Centre, and Ontario Addiction Treatment Centres.


'/>"/>

Contact: Veronica McGuire
vmcguir@mcmaster.ca
90-552-591-402-2169
McMaster University
Source:Eurekalert

Related medicine news :

1. Methadone programs can be key in educating, treating HCV patients
2. Long-term methadone treatment can affect nerve cells in brain
3. Testosterone Therapy Lawsuits: AndroGel Manufacturer Files Petition Against FDA's Decision on Generic Testosterone Treatment Drug
4. Millennium Treatment Group Sees Decline in DUI Rates
5. Testosterone Treatment Lawsuit News: Federal Court OverseeingTestosterone Litigation Convenes Conference to Discuss Pretrial Management, Bernstein Liebhard LLP Reports
6. Backs in Action Wellness Center Now Provides Specialized Pregnancy Back Pain Treatment
7. Increasing Demand for Skin Resurfacing Treatments: U.S. Fractional Laser Systems Market Led by Valeant, Lumenis and Syneron
8. University Of Iowa Celebrates The Dedication Of The Fraternal Order Of Eagles Diabetes Research Center - 100 Researchers Help Identify New Treatments & Cures For Diabetes
9. Diet Doc’s Medical Weight Loss Programs Announces the Best Diet for Fast Weight Loss with Hormone Treatments and Tailor Made Diet Plans
10. Diagnosing Balance Disorders Improves Treatment Outcomes for Patients Experiencing Dizziness, Vertigo
11. Millennium Treatment Group Sees Increase in Marijuana Use Among Youth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... 27, 2016 , ... With a team of certified experts, ... Aside from its GMP accreditation, Validation Center is also a registered authority of ... and staff. , Validation Center is ISO17025 accredited and only offers its clients ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... and clinical outcomes, hosted members and suppliers for its inaugural Member Conference at ... on their mission of elevating the operational health of America’s healthcare providers. , ...
(Date:5/26/2016)... ... 2016 , ... Cardiac arrhythmia is a common complication following ... survival, reports a team of UPMC researchers in the largest study of its ... Thoracic and Cardiovascular Surgery, provide critical information that will hopefully lead to better ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... An April ... American families. , The 550 employees of Sun Health Senior Living (SHSL) ... Aetna that reduces their doctor and prescription copays for the year, while holding the ...
(Date:5/26/2016)... ... ... The Lung Institute has partnered with the Gulfcoast North Area ... at their clinic in downtown Tampa. The class is complimentary for the public. Register ... a free downloadable 4 Week Smoking Cessation Guide for those who are ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... May 24, 2016 Niederländische ... gebracht, die es Ärzten erlaubt, ihre Expertise weltweit ... MDLinking kombiniert Live Streaming mit einer Instant-Messaging-Funktion und ... kommunizieren. Mediziner in Europa, Afrika, Asien und den ... für die Plattform registriert. Information und ...
(Date:5/24/2016)...   , Study met both ... in , Excellent plus Good ... of the ascending colon   ,      ... announced new positive data from the phase III MORA study for ... litre PEG with ascorbate. The study met both primary endpoints showing ...
(Date:5/24/2016)... 2016  NxStage Medical, Inc. (Nasdaq: NXTM ... renal care, today announced that Jeffrey H. Burbank ... following schedule of investor conferences. Where applicable, a webcast ... http://ir.nxstage.com/ .   ... NY           Friday, June 10, 2016 1:30 p.m. ET ...
Breaking Medicine Technology: