Navigation Links
Methadone treatment suppresses testosterone in opioid addicts
Date:8/26/2014

HAMILTON, ON (Aug. 26, 2014) Treatment for opioid addiction tampers with the testosterone levels of male but not female opioid users, McMaster University research has shown.

In a paper published today by the journal Scientific Reports, the researchers say addiction treatment may need to change to address the side-effect.

The study found men using methadone, which is used for opioid addiction treatment, have significantly suppressed testosterone levels of about a quarter of the testosterone of men not using opioids. In women using methadone for addiction treatment, testosterone levels were not significantly impacted, even considering the menstrual cycle.

Low testosterone in men has been associated with poor quality of life as well as erectile dysfunction, fatigue, and mood disturbances.

"We expect that treating testosterone deficiency will improve outcomes of methadone treatment for patients, including treatment response and retention," said Dr. Zena Samaan, principal investigator of the study.

"Doctors should also ensure the patients are being prescribed the lowest dose of opioids including methadone for effective treatment to minimize testosterone suppression."

She added that this is a particular issue in Canada, the second largest consumer of opioids in the world.

Dr. Samaan is an associate professor of the psychiatry and behavioural neurosciences department of McMaster's Michael G. DeGroote School of Medicine.

The study involved information from 231 patients with opioid dependence receiving methadone in Ontario, as well as 783 Ontarians not using opioids. It was funded by the Drug Safety and Effectiveness Network of the Canadian Institutes of Health Research and the McMaster Department of Psychiatry and Behavioural Neurosciences. The study was conducted by the Population Genomics Program of McMaster's Chanchlani Research Centre, and Ontario Addiction Treatment Centres.


'/>"/>

Contact: Veronica McGuire
vmcguir@mcmaster.ca
90-552-591-402-2169
McMaster University
Source:Eurekalert

Related medicine news :

1. Methadone programs can be key in educating, treating HCV patients
2. Long-term methadone treatment can affect nerve cells in brain
3. Testosterone Therapy Lawsuits: AndroGel Manufacturer Files Petition Against FDA's Decision on Generic Testosterone Treatment Drug
4. Millennium Treatment Group Sees Decline in DUI Rates
5. Testosterone Treatment Lawsuit News: Federal Court OverseeingTestosterone Litigation Convenes Conference to Discuss Pretrial Management, Bernstein Liebhard LLP Reports
6. Backs in Action Wellness Center Now Provides Specialized Pregnancy Back Pain Treatment
7. Increasing Demand for Skin Resurfacing Treatments: U.S. Fractional Laser Systems Market Led by Valeant, Lumenis and Syneron
8. University Of Iowa Celebrates The Dedication Of The Fraternal Order Of Eagles Diabetes Research Center - 100 Researchers Help Identify New Treatments & Cures For Diabetes
9. Diet Doc’s Medical Weight Loss Programs Announces the Best Diet for Fast Weight Loss with Hormone Treatments and Tailor Made Diet Plans
10. Diagnosing Balance Disorders Improves Treatment Outcomes for Patients Experiencing Dizziness, Vertigo
11. Millennium Treatment Group Sees Increase in Marijuana Use Among Youth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... ... , ... "I have gout, and I wanted to treat it naturally," said ... to relieve gout and pain caused by varicose veins. I drank it every morning ... relieved what VA doctors called the worst sinusitis case they'd seen and relieved gas, ...
(Date:12/9/2016)... ... December 09, 2016 , ... The Holy Name Medical Center ... NY, on December 3rd, to benefit Holy Name Medical Center's programs and services. ... raised over $1 million - the largest event in the Center's history, both ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... by the Undersea and Hyperbaric Medical Society (UHMS), the leading authority in hyperbaric ... patient safety. Only a few hospitals and facilities have earned this distinction. This ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Therapy Management (MTM), adherence, and other pharmacist-delivered patient care services, has announced the ... and Eric Hoessel to vice president of sales. , Litsinger joined Mirixa ...
(Date:12/8/2016)... ... 08, 2016 , ... SunView Software aims to redefine IT ... both engaging and easy to use. Coming off the heels of a successful ... its plans to roll out new AI-powered self-service enhancements to help organizations implement ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... 9, 2016 Research and Markets has ... report to their offering. ... The report forecasts the global optical transceiver market ... The report covers the present scenario and the ... calculate the market size, the report considers the revenue generated from ...
(Date:12/9/2016)... aTyr Pharma, Inc. (Nasdaq: LIFE ), a biotherapeutics company ... severe, rare diseases, today announced that senior management will participate in ... Conference at the InterContinental Barclay Hotel in New York ... ET. About aTyr Pharma ... aTyr Pharma is engaged in the ...
(Date:12/9/2016)... Bermuda , Dec. 9, 2016  Axovant ... leading clinical-stage biopharmaceutical company focused on the treatment ... the data from a Phase 2b trial evaluating ... care donepezil, compared with donepezil plus placebo in ... that the addition of intepirdine to treatment was ...
Breaking Medicine Technology: