Navigation Links
Metformin may lower cancer risk in people with Type 2 diabetes

A commonly prescribed diabetes drug, metformin, reduces the overall cancer risk in people with Type 2 diabetes, a large systematic review study finds. The results will be presented Monday at The Endocrine Society's 94th Annual Meeting in Houston.

"Type 2 diabetes increases the risk for several types of cancer," said lead author Diego Espinoza-Peralta, MD, an endocrinologist with Mexico's National Institute of Medical Sciences and Nutrition (Instituto Nacional de Ciencias Medicas y Nutricion) in Mexico City. "Our findings suggest that the regular use of metformina low-cost medication reduces this risk, compared with not taking metformin."

Espinoza-Peralta and his colleagues conducted a systematic review and meta-analysis, or combined statistical analysis, of reported studies that evaluated cancer risk in patients with Type 2 diabetes. They analyzed seven relevant studies that included more than 32,400 Type 2 diabetic patients who had no other known condition that increased their cancer risk.

The investigators found that the odds of getting any type of cancer was 0.62 times lessan estimated 38 percent relative risk reductionwith daily continuous use of metformin than for those with no exposure to metformin.

"This risk reduction with metformin use extended to certain types of cancers, specifically colon and breast cancer," Espinoza-Peralta said.

Colorectal cancer and breast cancer are among the cancers that studies have found to occur more often in people with Type 2 diabetes. There was no risk reduction, however, in pancreatic cancer, another type of cancer for which people with Type 2 diabetes are at increased risk, the authors reported.

Metformin, which is the standard recommended initial treatment of Type 2 diabetes, may protect against cancer because it regulates activity of an enzyme that suppresses cell growth, according to Espinoza-Peralta.

"There is growing evidence that metformin brings more benefits to diabetic patients beyond glucose control," he said.


Contact: Aaron Lohr
The Endocrine Society

Related medicine news :

1. Value of Metformin, Insulin Combo for Type 2 Diabetes Questioned
2. Metformin Outperforms Common Class of Diabetes Drugs in Study
3. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
4. Tree nut consumption associated with lower body weight and lower prevalence of health risks
5. Diagnostic yield of colonoscopy for melena after nondiagnostic upper endoscopy is lower than previously reported
6. Everyday Activities Might Lower Alzheimers Risk
7. Modest alcohol consumption lowers risk and severity of liver disease
8. Lower Risk for Bowel Obstruction With Less Invasive Surgery: Study
9. CAM therapy combined with conventional medical care may improve treatment of lower back pain
10. Blood pressure drugs linked with lower PTSD symptoms
11. Lower-Dose Radioiodine Effective Against Thyroid Cancer
Post Your Comments:
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... a startling report released today, National Safety Council research ... proven plan to eliminate prescription opioid overdoses. Prescription Nation ... tackling the worst drug crisis in recorded U.S. history, assigned a ... , New Mexico , Tennessee ... failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
Breaking Medicine Technology: