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Metal stents are effective treatment for blocked bile ducts
Date:3/20/2013

stone related disease, chronic pancreatitis 80.7 percent, 80 percent in other etiology and, in more complex anastomotic strictures cases, it was 61.2 percent successful. Interestingly, patients who had stents placed for more than three months were 4.3 times more likely to have resolved strictures, while those with non-migrated stents were 5.4 times more likely to have resolved strictures. Also, nearly 73 percent of metal stents were successfully removed after an average of three months.

"Fully covered self-expanding metal stents are emerging as a promising therapeutic option in the treatment of benign bile duct strictures," Dr. Kahaleh says. "We found very acceptable, high rates of stricture resolution after the use and removal of metal stents in all types of patients groups. Also, those with longer duration of stent placement that didn't migrate had an increased likelihood of stricture resolution."

Current data and the FDA support the use of plastic stents in the endoscopic treatment of benign bile duct blockages. However, this current research study reports previous plastic stenting doesn't always hold up. In fact, the study shows failed plastic stenting had been performed in more than half of the study patients who underwent implant of metal stents. Also, researchers report previous plastic stenting was associated with a decreased rate of stricture resolution.

"It's time to revisit the therapeutic options we offer our patients for this often sudden and painful benign bile duct narrowing and blockages," says Dr. Kahaleh. "Our study shows that any type of benign biliary stricture except those related to liver transplant can be treated with these metal stents, and metal stents may just do a better job fixing benign strictures then plastic stents."

The researchers report FCSEMS did have some minor complications in the patient population studied. After implantation, complications included stent migration (10.5 percent), post-pro
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Contact: Lauren Woods
Law2014@med.cornell.edu
646-317-7401
Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

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