Navigation Links
Metabolic syndrome may increase risk for liver cancer
Date:4/3/2011

ORLANDO, Fla. Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

Katherine McGlynn, Ph.D., a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.

According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn.

"The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."

For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.

Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intraheptic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Mediterranean Diet Reduces Risk of Metabolic Syndrome
2. Metabolic syndrome found in 52 percent of patients after liver transplantation
3. Vitamins C and E linked to metabolic syndrome in low-income Ecuadorians
4. Loud snoring and insomnia symptoms predict the development of the metabolic syndrome
5. Moderate alcohol consumption lowers the risk of metabolic diseases
6. Metabolic status before pregnancy predicts subsequent gestational diabetes
7. UC San Diego researchers find cause of metabolic disease -- and possible cure
8. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
9. Low vitamin D linked to the metabolic syndrome in elderly people
10. Metabolic syndrome in living kidney donors worsens function of remaining kidney
11. Vitamin D Deficiency Linked to Diabetes, Metabolic Syndrome in Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... , ... February 11, 2016 , ... According to an ... product marketed as a weight loss dietary supplement, is being recalled due to the ... Hills Physicians, because there is not a single supplement on the market proven to ...
(Date:2/11/2016)... (PRWEB) , ... February 11, 2016 , ... ... participated in the American Osteopathic Association’s (AOA) Match Program Tuesday, February 9, taking ... Program places students into osteopathic graduate medical education positions across the country. Of ...
(Date:2/11/2016)... Beach, CA (PRWEB) , ... February 11, 2016 ... ... his extensive experience performing a wide range of cosmetic procedures. Along with performing ... improving the efficiency and results of many cosmetic procedures. One of the most ...
(Date:2/11/2016)... ... 2016 , ... The Journal of Pain Research has seen a ... uses data taken from the Scopus database (Elsevier B.V.) and is a measure of ... the journal over a three year period and also the importance of the journals ...
(Date:2/11/2016)... ... ... The president released a FY 2017 budget request on Tuesday that includes $48.8 ... burden to military beneficiaries. , MOAA’s president, retired Air Force Lt. Gen. Dana ... quantifiable benefit fixes mixed with numerous beneficiary fee hikes. , “We were hoping to ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... OAKLAND, Calif. , Feb. 11, 2016  Walgreens ... stores across 39 states and Washington, D.C. ... in a move that was commended by shareholder advocacy organization ... President at As You Sow. "Many people hold on to ... options, which can have tragic consequences." --> ...
(Date:2/11/2016)... Feb. 11, 2016  MiMedx Group, Inc. (NASDAQ: ... amniotic membrane and other birth tissues, human skin and ... and market advanced products and therapies, announced today that ... Global Healthcare Conference in New York ... Michael J. Senken , Chief Financial Officer and ...
(Date:2/11/2016)... fevereiro de 2016  A Proliant Biologicals anuncia, ... soroalbumina bovina (BSA -- Bovine Serum Albumin ... Ilha Norte da Nova Zelândia, em Feilding. ... fábrica da Proliant nos EUA, localizada em ... instalação dos equipamentos foram feitos de forma a ...
Breaking Medicine Technology: