Navigation Links
Metabolic syndrome may increase risk for liver cancer
Date:4/3/2011

ORLANDO, Fla. Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

Katherine McGlynn, Ph.D., a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.

According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn.

"The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."

For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.

Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intraheptic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Mediterranean Diet Reduces Risk of Metabolic Syndrome
2. Metabolic syndrome found in 52 percent of patients after liver transplantation
3. Vitamins C and E linked to metabolic syndrome in low-income Ecuadorians
4. Loud snoring and insomnia symptoms predict the development of the metabolic syndrome
5. Moderate alcohol consumption lowers the risk of metabolic diseases
6. Metabolic status before pregnancy predicts subsequent gestational diabetes
7. UC San Diego researchers find cause of metabolic disease -- and possible cure
8. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
9. Low vitamin D linked to the metabolic syndrome in elderly people
10. Metabolic syndrome in living kidney donors worsens function of remaining kidney
11. Vitamin D Deficiency Linked to Diabetes, Metabolic Syndrome in Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... ... Excessive panting in the car or cowering when new guests arrive are ... only manifests itself as trembling or ‘tail between the legs,’ but a pet ... about it,” says Dr. Jim Lowe, technical services veterinarian for Tomlyn pet health products ...
(Date:5/3/2016)... ... May 03, 2016 , ... Diagnotes, a leader ... Health, a three hospital system in South Carolina, to provide its secure mobile ... technology that enhances communication, drives workflow efficiencies and improves provider and patient satisfaction,” ...
(Date:5/3/2016)... ... , ... Boston Children’s Hospital today announced its new pediatric Simulation (SIM) Center ... rare procedures in an environment that looks and feels real. , Located in the ... and “hackers” to develop and test new devices or software platforms and see how ...
(Date:5/3/2016)... ... ... Each year, about 800,000 people suffer from cerebral vascular accidents, or strokes. ... one death every four minutes. Many people who survive a stroke are left ... video series called “Your Brain,” in conjunction with its medical journal “Balance,” in order ...
(Date:5/3/2016)... ... 2016 , ... Ogawa World USA introduced the first of its kind ... Smart Application. The Smart 3D combines the best in technological advancement, design, and massage ... and specialized massage program, each user has a tailored experience unparalleled by any other ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... -- Research and Markets has announced the ... 2016-2020" report to their offering.      ... global plastic surgery products market is expected to grow ... , ,The growing adoption of laser in aesthetics is ... market. Lasers are used to treat a broad range ...
(Date:4/28/2016)... 2016 Treato , the ... announced today that it has been named a Cool ... in Life Sciences, 2016, Stephen Davies , ... focuses on life-science- oriented analytics, algorithms and smart machine ... doctors, confirm medication ingestion, and analyze unstructured information.   ...
(Date:4/28/2016)... 28, 2016   Acsis , a leading provider ... IT market research and advisory firm IDC has named ... MarketScape: Worldwide Pharmaceutical Track and Trace Software 2016 Vendor ... an assessment of the capabilities and business strategies of ... market. Logo - http://photos.prnewswire.com/prnh/20160427/360791LOGO ...
Breaking Medicine Technology: