Navigation Links
Metabolic syndrome may increase risk for liver cancer
Date:4/3/2011

ORLANDO, Fla. Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

Katherine McGlynn, Ph.D., a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.

According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn.

"The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."

For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.

Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intraheptic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Mediterranean Diet Reduces Risk of Metabolic Syndrome
2. Metabolic syndrome found in 52 percent of patients after liver transplantation
3. Vitamins C and E linked to metabolic syndrome in low-income Ecuadorians
4. Loud snoring and insomnia symptoms predict the development of the metabolic syndrome
5. Moderate alcohol consumption lowers the risk of metabolic diseases
6. Metabolic status before pregnancy predicts subsequent gestational diabetes
7. UC San Diego researchers find cause of metabolic disease -- and possible cure
8. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
9. Low vitamin D linked to the metabolic syndrome in elderly people
10. Metabolic syndrome in living kidney donors worsens function of remaining kidney
11. Vitamin D Deficiency Linked to Diabetes, Metabolic Syndrome in Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... New York, NY (PRWEB) , ... October 13, 2017 , ... ... most influential people in business to advocate for action towards gender equality at their ... 18,000 views from around the globe, and reached a social audience of over 3 ...
(Date:10/13/2017)... ... 13, 2017 , ... “The Journey: From the Mountains to the Mission Field”: ... souls in the Philippines. “The Journey: From the Mountains to the Mission Field” is ... Bible. She has taught all ages and currently teaches a class of ladies at ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., ... vaccine design, and immune-engineering today announced the launch ... the development of personalized therapeutic cancer vaccines. EpiVax ... provided exclusive access to enabling technologies to the ... MBA will lead EpiVax Oncology as Chief Executive ...
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
Breaking Medicine Technology: