Navigation Links
Metabolic disorders predict the hardening of the arterial walls already in childhood
Date:4/25/2013

Metabolic disorders, such as excess abdominal fat, raised blood pressure, higher levels of insulin, glucose and triglycerides and lower levels of the beneficial HDL cholesterol can be found in children as young as 6 to 8 years of age, according to a study carried out at the University of Eastern Finland. These metabolic risk factors often accumulate in overweight children and, in the newly published study, this accumulation was linked with mild artery wall stiffness. Of single disorders, higher levels of insulin, triglyceride and blood pressure were associated with artery wall stiffness. In addition, boys with excess abdominal fat and higher blood pressure levels were related to a reduced arterial dilation after maximal exercise in a bicycle test. The results were published today in Circulation Journal.

The researchers analyzed the relations of overweight, impaired glucose and fat metabolism and blood pressure to artery wall stiffness and arterial dilation capacity in 173 healthy children aged 6 to 8 years in Kuopio, eastern Finland. The study comprised part of the wider Physical Activity and Nutrition in Children (PANIC) study, which is carried out by a research group in the Institute of Biomedicine at the University of Eastern Finland. The PANIC study provides novel and scientifically valuable information on children's physical activity, nutrition, fitness, body composition, metabolism, vascular function, learning, oral health, sleep, pain and other factors of the quality of life. The original subject group was a population sample of 512 children from the city of Kuopio who were 6𔃆 years of age during the baseline examinations carried out between 2007 and 2009. The children underwent a wide variety of measurements relating to their lifestyle, health and well-being. Furthermore, their artery wall stiffness and arterial function were measured by the pulse contour analysis of the finger arterial waveform.

Arterial stiffness and reduced arterial dilation predict atherosclerosis, i.e. the hardening of the arteries, and resulting vascular diseases such as coronary artery disease, cerebral infarctions and lower extremity arterial disease. The newly published results are scientifically significant, as they suggest that metabolic disorders developing already in childhood could cause mild arterial stiffness, thus impairing vascular health. These results emphasize the importance of lifestyle improvement already in childhood in order to prevent metabolic and vascular dysfunction and resulting atherosclerotic events.


'/>"/>

Contact: Timo A. Lakka
timo.lakka@uef.fi
358-407-707-329
University of Eastern Finland
Source:Eurekalert

Related medicine news :

1. Epoxide hydrolase inhibition and Thiazolidinediones: A therapy for cardiometabolic syndrome
2. Monounsaturated fats reduce metabolic syndrome risk
3. Monosaturated fats reduce metabolic syndrome risk
4. Altman Fitness Launches the Metabolic Typing - Customized Nutrition Plan
5. EU funds research project on obesity and metabolic complications
6. Selexis SA Announces Publication in Metabolic Engineering of Data Demonstrating Improvement of Therapeutic Protein Secretion with Engineered CHO Cells
7. Recon 2 modeling may help tailor treatments for patients with metabolic diseases, cancer
8. Altman Fitness Announces Metabolic Typing for Weight Loss
9. Birth order linked to increased risk of diabetes, metabolic disorders
10. Are gender and ethnicity risk factors for metabolic syndrome in children?
11. Metabolic biomarkers for preventive molecular medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, and ... in the eye of the beholder, according to experts who offered insights and commentary ... of Managed Care. For the full issue, click here . , For the ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are ... with endometriosis. These women need a treatment plan to not only alleviate symptoms ... can help for preservation of fertility and ultimately achieving a pregnancy. The specialists ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Dialysis Devices Global Market - Forecast to 2022" report ... is the treatment method for the patients with kidney failure, ... and excess fluid from the patient,s blood and thus the ... sodium, potassium and chloride in balance. Increasing ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic ... Coating, Parenteral) - Global Forecast to 2021" report ... The global pharmaceutical excipients market is projected to ... of 6.1% in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: