Navigation Links
Metabolic bone disease in cirrhosis patients
Date:8/10/2009

Long-standing liver disease has long been recognized to result in fragile bones with increased risk of fractures. In various international studies, the overall incidence has varied from 11% to 48%, with a fracture rate of 3%-44%. However, the reason for this is poorly understood. With liver transplantation becoming a viable option in liver disease and offering complete cure and long-term survival, bone disease is becoming the major determinant of survival and quality of life in these patients.

A research article to be published on July 28, 2009 in the World Journal of Gastroenterology addresses this question. This research team was led by Tushar R Bandgar from KEM Hospital, India.

They found that low bone formation and increased resorption led to fragile bones in these patients. Contributing factors identified were inadequate sunlight exposure, reduced physical activity, low body weight, vitamin D deficiency and low level of testosterone. They also demonstrated that the severity of bone loss was accelerated in patients with low IGF-1 level. IGF-1 is normally synthesized in the liver and its synthesis is affected early in cirrhosis. The present study also found that the increased estrogen level seen in cirrhosis was protective against osteopenia.

These results shed new light on bone disorders seen in patients with cirrhosis. As most of the factors identified are correctable or treatable, it should provide additional help in treatment of these patients, such that they have better quality of life and survival.


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Metabolic syndrome heightens risk for development of uric-acid kidney stones
2. Abaxis Announces First Ever CLIA-Waived Comprehensive Metabolic Panel
3. Low-carb diet reduces inflammation and blood saturated fat in metabolic syndrome
4. Unrelated Cord Blood Helps Infants With Metabolic Disorders
5. Moderate Exercise Cuts Risk of Metabolic Syndrome
6. Pediatricians call for a cohesive definition of metabolic syndrome in children
7. Burgers, fries, diet soda: Metabolic syndrome blue-plate special
8. Metabolic syndrome affects nearly 1 in 10 US teens
9. Diuretics Best for Hypertension and Metabolic Syndrome
10. Diuretics excel in drug comparison trial involving hypertension/metabolic syndrome
11. Exercise and caloric restriction may be treatment method for metabolic syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... (PRWEB) January 22, 2015 A ... Sports Medicine flagship journal Medicine & Science in ... before exercise may help reduce gastrointestinal (GI) problems ... , Participants in the double-blind, placebo-controlled study ...
(Date:1/22/2015)... 2015 Recently, Weddingshe.com has added many trendy ... announced its highest annual revenues in the past three years. ... glamorous wedding dresses. , According to the sales manager of ... promotions for them in 2015. This point can be reflected ...
(Date:1/22/2015)... Colorado (PRWEB) January 22, 2015 Four years since ... Queen – which coincided with the marriage of Avasa & Matthew ... THE ROAD, which is scheduled for release through White Swan Records ... message that there is a sacred path available to all of ...
(Date:1/22/2015)... EBSCO Information Services (EBSCO) and the American ... effort to further promote visibility and adoption of the top ... AMA journals available via its subscription services, EBSCO will now ... , Long known as both a subscription agency and ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store ... announces its latest collection of wedding dresses , and ... issue is the wedding dress on your big day; the ... life. Every bride wants to find the most suitable wedding ...
Breaking Medicine News(10 mins):Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... Study finds people struggling with rejection can spot a phony ... just get shot down by a co-worker who has no ... side: New research suggests that rejection may boost your ability ... about being rejected recognized 80 percent of fake human smiles ...
... evaluation and performance measures part of URAC,s Comprehensive Wellness ... WASHINGTON, Nov. 19 URAC announced today that its ... its Comprehensive Wellness Accreditation program. These innovative standards ... organizations have to ensuring the health and productivity of ...
... Changing Times,Vitamins, Inc., (Pink Sheets: SGTB) announced ... King Features Syndicate, Division of Hearst,Corporation, one of ... Changing Times Vitamins (CTV) the right to produce ... use Popeye(R) and associated characters for sale,and promotion ...
... ALLEGAN, Mich., Nov. 19 Perrigo Company,(Nasdaq: ... litigation,brought by Sanofi-Aventis (NYSE: SNY ) against ... BRL ). The suit was brought ... Barr,s filing of an ANDA,for Triamcinolone Acetonide Nasal Spray ...
... Tenn., Nov. 19 HealthLeaders-InterStudy, a,leading provider ... while,radiology costs have stabilized since first coming ... costs quickly rise again. In several recent ... that to,control costs, insurers continue to rely ...
... has Decreased By More than One-Fourth , ... federal government show that cigarette consumption in the U.S. has ... over the past decade, which marks a major milestone in ... of Attorneys General (NAAG) and the American Legacy Foundation (R) ...
Cached Medicine News:Health News:Not All Smiles Are Created Equal 2Health News:Not All Smiles Are Created Equal 3Health News:URAC Announces Accreditation Standards for Comprehensive Wellness Programs 2Health News:URAC Announces Accreditation Standards for Comprehensive Wellness Programs 3Health News:URAC Announces Accreditation Standards for Comprehensive Wellness Programs 4Health News:King Features Syndicate and Changing Times Vitamins Sign Licensing Agreement for Popeye(R) the Sailor Man in the Water Drink Category. 2Health News:King Features Syndicate and Changing Times Vitamins Sign Licensing Agreement for Popeye(R) the Sailor Man in the Water Drink Category. 3Health News:Perrigo Acknowledges Settlement of NASACORT(R) AQ Nasal Spray Patent Litigation 2Health News:Perrigo Acknowledges Settlement of NASACORT(R) AQ Nasal Spray Patent Litigation 3Health News:Insurers Employ Multiple Solutions to Avoid Radiology Expense Spike 2Health News:Insurers Employ Multiple Solutions to Avoid Radiology Expense Spike 3Health News:America Reaches Major Anti-Smoking Milestone 2Health News:America Reaches Major Anti-Smoking Milestone 3Health News:America Reaches Major Anti-Smoking Milestone 4Health News:America Reaches Major Anti-Smoking Milestone 5
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
(Date:1/22/2015)... , Jan. 22, 2015  BiOptix is pleased to ... as Vice President of Chemistry and Biochemistry. Scott joins the ... AstraZeneca Pharmaceuticals, and Amgen throughout the course of his ... "Scott is a nationally recognized thought leader ...
(Date:1/22/2015)... 22, 2015  Bio-Techne Corporation (NASDAQ: TECH ) ... member of the new Simple Plex platform through its ... represents the re-branding of the previously acquired CyPlex instrument ... is a transformative immunoassay technology which integrates an innovatively ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3
Supplied sterile in peel-open packages. Intended for one-time use....
Supplied sterile in peel-open packages. Intended for one-time use....
Supplied sterile in peel-open packages. Intended for one-time use....
Used for percutaneous nephrostomy. Supplied sterile in peel-open packages. Intended for one-time use....
Medicine Products: