Navigation Links
Metabolic biomarkers for preventive molecular medicine
Date:12/4/2012

increased levels of telomerase those that age more slowly, according to a study published recently by the Blasco laboratory in the journal EMBO Molecular Medicine, they observed that the metabolic footprint was very similar to that of the youngest mice. When they studied mice with telomerase deficiencies those that aged more quickly, they observed a metabolic profile very similar to that of older animals.

Recent studies in humans indicate a possible relationship between the metabolism and life expectancy. "Our large-scale analysis, that analyses a larger amount of metabolites than has ever been studied before, validates the theory that the metabolome faithfully shows cells' biological clocks", says Mato.

NEW BIOMARKERS TO EVALUATE THE STATE OF HEALTH

Ageing is characterised in large part by metabolic decline that implies loss of hepatic, renal, coronary or cardiac function, as well as an increased risk of suffering cancer. In fact, some of the 48 metabolites identified in the study have previously been related to illnesses associated with age, such as Alzheimer's or cardiovascular diseases.

The results of this research may be useful for predicting the overall state of health in humans, via the extraction of a small blood sample. They might also be useful for preventing illnesses related to the passage of time, which make up the majority of deadly diseases in developed countries.

From these results, the researchers are also looking into searching for diagnostic biomarkers that are associated to high-impact socioeconomic illnesses such as diabetes, obesity or cardiovascular diseases.


'/>"/>
Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Metabolic protein launches sugar feast that nurtures brain tumors
2. New technology for a more efficient treatment of Pompe disease and other metabolic disorders
3. Moffitt Cancer Center researchers identify novel metabolic programs driving aggressive brain tumors
4. Metabolic syndrome makes a difference in hormone therapy risk
5. In obesity, a micro-RNA causes metabolic problems
6. Obese people can be metabolically healthy and in good shape
7. Study links breast cancer risk to early-life diet and metabolic syndrome
8. Metabolic engineer synthesizes key breast milk ingredient, makes research possible
9. Obesity and metabolic syndrome associated with impaired brain function in adolescents
10. New research uncovers diverse metabolic roles for PML tumor suppressor gene
11. Ancestral link places Mexican-Americans at greater risk for metabolic disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... with early-stage breast cancer in California, the percentage undergoing ... although this procedure was not associated with a lower ... to a study in the September 3 issue of ... for the removal of one breast was associated with ... examined in the study. , Randomized trials have demonstrated ...
(Date:9/2/2014)... Dallas, TX (PRWEB) September 02, 2014 The ... proudly presenting Music4Miracles on Sept. 14th, 2014 during Spinal Cord ... Mark McKinney, Aubrey Lynn England, and Chuck Ligon. Linear Automotive ... Rod and Gasser show. , Doors open at 2pm. The ... fee which includes one free pass to the concert. There ...
(Date:9/2/2014)... Sept. 2, 2014 (HealthDay News) -- Melatonin supplements did ... hip fractures, a new study found. Many older ... delirium due to disruption of their normal sleep-wake cycle. ... factor that contributes to delirium, but there has been ... patients. This study included 378 patients, average age ...
(Date:9/2/2014)... ANGELES (Sept. 2, 2014) Measuring the levels of sex ... a sudden cardiac arrest, a heart rhythm disorder that is ... study, published online by the peer-reviewed journal Heart Rhythm ... sex hormone, were found in men who had a sudden ... hormone, were strongly associated with greater chances of having a ...
(Date:9/2/2014)... When weather conditions are right, tornadoes can ... behind a path of destruction. In fact, the United States ... 1,253 tornadoes per year. Rainbow International offers the following safety ... strikes., , Select a safe place such ... home with no windows to stay during the storm. If ...
Breaking Medicine News(10 mins):Health News:Increase seen in use of double mastectomy 2Health News:Increase seen in use of double mastectomy 3Health News:Gas Monkey Hosts Concert in Dallas Benefiting Dream2Walk Foundation with Linear Automotive 2Health News:Study links sex hormone levels in the blood to risk of sudden cardiac arrest 2Health News:Act Quickly in Case of Tornado: Rainbow International® Offers Tips on How to Be Prepared for a Tornado 2
... University School of Medicine (BUSM) have demonstrated that commensal ... inducers of human airway epithelial cell responses as compared ... a Neisserial outer membrane component appears to play a ... with a receptor on the surface of human airway ...
... Mozes HealthDay Reporter , MONDAY, Nov. 22 ... well-known antioxidant cousin, alpha-carotene, in fruits and vegetables can ... heart disease and cancer, new research suggests. ... -- because of the red, yellow and orange coloring ...
... Doctors at the University of Colorado School of Medicine were ... of a 64-year-old Colorado man. They extracted cells from the ... the biopsy results were inconclusive. Even a few months ... remove all or part of the thyroid. At least this ...
... become aware of the dangers of excessive fructose in diet. ... the Journal of the American Society of Nephrology ... may be. Richard J. Johnson, MD and Takahiko ... Colorado) provide a concise overview of recent clinical and experimental ...
... , MONDAY, Nov. 22 (HealthDay News) -- Increased ... United States billions of dollars a year in medical ... Medical Expenditure Panel Survey, the investigators estimated how reductions ... related conditions would affect health care spending. The ...
... Holohan HealthDay Reporter , MONDAY, Nov. 22 ... can fuel each other, a new study shows. ... subjects who were depressed had a much higher risk ... significantly higher risk of depression, compared to healthy study ...
Cached Medicine News:Health News:BUSM investigates cellular mechanisms leading to immune response in airway epithelium 2Health News:Eat Your Fruits & Veggies for Longer Life 2Health News:Eat Your Fruits & Veggies for Longer Life 3Health News:Genomic 'markers' may head off thousands of thyroid surgeries 2Health News:Disease Prevention Could Save U.S. Billions of Dollars Annually 2Health News:Diabetes, Depression Can Be Two-Way Street 2Health News:Diabetes, Depression Can Be Two-Way Street 3
(Date:9/2/2014)... Sept. 2, 2014 Reportlinker.com announces that ... its catalogue: Asia-Pacific Infusion Therapy ... Abstract: The ... included volumetric infusion pumps, syringe infusion pumps, disposable ... stopcocks. These categories are segmented based on the ...
(Date:9/2/2014)... -- Reportlinker.com announces that a new market research report is ... Taiwanese Markets for Minimally Invasive Spinal Devices ... market for MIS spinal devices in the ... a fast pace, albeit at different rates in different ... China , where MIS spinal fusion is ...
(Date:9/2/2014)... 2, 2014 Depomed, Inc. (Nasdaq: ... subject to market and other conditions, $230 million aggregate ... "Notes"). Depomed, Inc. ("Depomed") expects to grant the underwriters ... to an additional $34.5 million aggregate principal amount of ... Capital Markets, LLC will act as joint book-running managers ...
Breaking Medicine Technology:Asia-Pacific Infusion Therapy Device Market 2Asia-Pacific Infusion Therapy Device Market 3Asia-Pacific Infusion Therapy Device Market 4Asia-Pacific Infusion Therapy Device Market 5Asia-Pacific Infusion Therapy Device Market 6Asia-Pacific Infusion Therapy Device Market 7Asia-Pacific Infusion Therapy Device Market 8Asia-Pacific Infusion Therapy Device Market 9Asia-Pacific Infusion Therapy Device Market 10Asia-Pacific Infusion Therapy Device Market 11Asia-Pacific Infusion Therapy Device Market 12Asia-Pacific Infusion Therapy Device Market 13Asia-Pacific Infusion Therapy Device Market 14Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 2Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 3Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 4Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 5Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 6Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 7Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 8Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 9Depomed Announces Offering of $230 Million Convertible Senior Notes Due 2021 2Depomed Announces Offering of $230 Million Convertible Senior Notes Due 2021 3
... Oct. 9 Vical Incorporated,(Nasdaq: VICL ) ... mice demonstrated,the potential of its patented Vaxfectin(TM) adjuvant ... protein-based H5N1 pandemic influenza vaccine,currently stockpiled by the ... limited vaccine supplies to protect the greatest,number of ...
... Oct. 9 The Wellion Linus Blood Glucose,Monitoring ... recently received certification by the Netherlands Organization,for Applied ... group,founded in 1932 that thoroughly tests and inspects ... the CE Marking. "Receiving the TNO approval ...
Cached Medicine Technology:Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant 2Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant 3Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant 4WaveSense Blood Glucose Meter One of Few Brands to Pass Rigorous TNO Tests 2
Biomet® Arthrodesis Nail indications include: , Failed external fixation , Aseptic failed total knee arthroplasty , Periarticular fractures where repair is not possible , Limb salvage in tumor...
... The efficacy of treating upper ... been documented in many studies. , ... Humeral Nail System offers the benefits ... limited soft tissue dissection and early ...
... the worlds leading medical technology company ... management for more than a decade, ... Timer. The ACT Plus System is ... to determine coagulation endpoints in whole ...
... techniques have largely replaced the use of plates and ... use of rods or pins in the forearm or ... been no way to lock the pins or hold ... non-locked nail is back out of the implant. The ...
Medicine Products: