Navigation Links
Metabolic Syndrome Raises Colon Cancer Risk 75%
Date:10/10/2008

Finding suggests need for more careful screening for these patients, researcher says

FRIDAY, Oct. 10 (HealthDay News) -- Patients coping with metabolic syndrome have a 75 percent higher risk for developing colorectal cancer sometime in their lives, a new study suggests.

"Metabolic syndrome is a conglomeration of three or four diseases, that together can portend a worse prognosis for certain illnesses, including a number of cancers," said study co-author Dr. Donald Garrow, a clinical gastroenterology fellow at the Medical University of South Carolina in Charleston.

"But what has not been well-defined," he added, "is the associated risk for colorectal cancer. So this is one of the first -- and certainly the largest -- study to look specifically at this risk. And we found that there is indeed a higher risk for colorectal cancer in this population."

Garrow and his colleague, Dr. Mark Delegge, presented their findings last week at the American College of Gastroenterology scientific meeting, in Orlando, Fla.

The researchers noted that metabolic syndrome is a combination of three chronic conditions that are linked to being either overweight or obese: high blood pressure, diabetes and elevated cholesterol. The syndrome is already known to increase the risk for developing heart disease and stroke.

To gauge the degree to which having these conditions in concert might raise colon cancer risk as well, the authors reviewed data collected between 2000 and 2003 by the National Health Interview Survey. The nationwide survey is conducted annually by the National Center for Health Statistics.

The team focused on survey participants who had reported having a history of metabolic syndrome --almost 1,200 patients -- and those with a history of colorectal cancer -- 350 patients.

After controlling for mitigating factors such as age, race, gender, obesity, and smoking and drinking habits, a cross-referencing of disease data revealed that patients with metabolic syndrome did, in fact, bear a significantly higher risk for colorectal cancer.

"This is concerning, because colon cancer is a disease that is preventable if patients get screened as recommended," said Garrow. "So, we hope with this study will encourage patients with metabolic syndrome to adhere to screening guidelines."

Dr. George Chang, an assistant professor of surgical oncology at M.D. Anderson Cancer Center at the University of Texas in Houston, agreed.

"I think this kind of a study emphasizes the importance of screening, and importance of adhering to the current guidelines," he said. "What the study does not do is evaluate if patients with metabolic syndrome develop colon cancer at an earlier age. So, there is insufficient evidence here to necessarily change our screening recommendations to encourage metabolic syndrome patients specifically to go in for earlier screening than they would otherwise if they followed current guidelines."

"However, I think this certainly is an area that warrants further investigation," added Chang, "to see if we can better identify those patients who are at higher risk for colorectal cancer."

In a second study also presented at the meeting, researchers revealed that initiating colon cancer screening 10 years prior to Medicare eligibility at 65 appears to save $2 in health-care costs for every $1 spent.

The finding stems from an analysis conducted by Scott Tenner and his colleagues from the State University of New York and New York College of Osteopathic Medicine, after they administered free colonoscopies to 248 Brooklyn residents who had an average age of 55. The initiative was launched as part of a colon cancer screening program.

The program -- which determined that 45 percent of the patients had polyps of varying sizes, while five patients had early-stage colon cancer -- cost $390,000 to run. The team concluded that had the same patients waited until the age of 65 to get screened, the cost of screening and treating those who needed care a decade later would have ballooned to $1.3 million.

More information

For additional information on colon cancer risk factors, visit the American Cancer Society.



SOURCES: Donald Garrow, M.D., MSCR, clinical gastroenterology fellow, Medical University of South Carolina, Charleston; George Chang, M.D., assistant professor, surgical oncology, University of Texas M.D. Anderson Cancer Center, Houston; Oct. 3-8, 2008, American College of Gastroenterology scientific meeting, Orlando, Fla.


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Metabolic syndrome heightens risk for development of uric-acid kidney stones
2. Abaxis Announces First Ever CLIA-Waived Comprehensive Metabolic Panel
3. Low-carb diet reduces inflammation and blood saturated fat in metabolic syndrome
4. Unrelated Cord Blood Helps Infants With Metabolic Disorders
5. Moderate Exercise Cuts Risk of Metabolic Syndrome
6. Pediatricians call for a cohesive definition of metabolic syndrome in children
7. Burgers, fries, diet soda: Metabolic syndrome blue-plate special
8. Metabolic syndrome affects nearly 1 in 10 US teens
9. Diuretics Best for Hypertension and Metabolic Syndrome
10. Diuretics excel in drug comparison trial involving hypertension/metabolic syndrome
11. Exercise and caloric restriction may be treatment method for metabolic syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Metabolic Syndrome Raises Colon Cancer Risk 75%
(Date:5/26/2016)... D.C. (PRWEB) , ... May 26, 2016 , ... On ... men and women who lost their lives in military battle for the country. ... cards in 2015 to provide more programs that empower independence for disabled military veterans, ...
(Date:5/26/2016)... ... May 26, 2016 , ... MadgeTech will be showcasing its line of ... Warner, New Hampshire at the MadgeTech headquarters. With products sold in more than 100 ... government agencies, including NASA. , In 2012, NASA strategically set up 17 RHTemp101A ...
(Date:5/26/2016)... Los Angeles, CA (PRWEB) , ... May 26, 2016 , ... In an effort to ... Snapchat videos available to both Snapchat users and those who do not use the app. ... available on his new page, Dr. Mohebi Live . , Dr. Mohebi says, ...
(Date:5/26/2016)... ... May 26, 2016 , ... The Lung Institute has partnered ... cessation class starting June 6 at their clinic in downtown Tampa. The class is ... the Lung Institute has created a free downloadable 4 Week Smoking Cessation Guide ...
(Date:5/26/2016)... ... ... The MIAMI Institute for Age Management and Intervention celebrates Global Wellness Day with ... Adonis , Wellness Physician of the MIAMI Institute is certified by the American Academy ... , He also heads up FITTLab, the comprehensive medical testing lab located in The ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... 25, 2016 Inivata, a ... of circulating tumour DNA (ctDNA) analysis to improve ... of Professor Clive Morris as Chief ... the clinical development programme, scientific collaborations, and through ... significant improvements in clinical outcomes for patients. ...
(Date:5/24/2016)... May 24, 2016   ... beide primären Endpunkte und demonstriert Ebenbürtigkeit ... ‚ausgezeichneter plus guter , ... ,      (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ... neue positive Daten von der MORA-Studie der Phase ...
(Date:5/24/2016)... -- NxStage Medical, Inc. (Nasdaq: NXTM ), a ... today announced that Jeffrey H. Burbank , Chief ... of investor conferences. Where applicable, a webcast of the ...   ... Friday, June 10, 2016 1:30 p.m. ET ...
Breaking Medicine Technology: