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Merz Aesthetics, a Division of Merz Pharmaceuticals USA, Introduces a Universal Language of Aging for Use in Education, Research and Practice
Date:3/6/2009

static) and hyperkinetic (dynamic) forehead lines. The scale ratings are 0 for no wrinkles, 1 for no wrinkles present at rest but fine lines with facial expressions, 2 for fine wrinkles present at rest and deep lines with facial expression, 3 for fine wrinkles present at rest and deeper lines with facial expression and 4 for deeper wrinkles at rest and deeper furrows with facial expression.

During the development of the validation process the team of experts discussed the resulting scales. Every participant graded the scales twice, with an overnight break in between. Intra and interrater variability analysis was performed. The variability analysis also was depicted in a bubble plot, which is an informative way of comparing grading between raters.

About Merz Aesthetics

Merz Aesthetics is the new division of Merz Pharmaceuticals, part of the Merz group of companies based in Frankfurt Germany, with a 100-year history of compassion and innovation in healthcare. The ongoing development of The Merz Scales represents the company's ongoing, deep commitment to education and research in health and beauty.

Merz Aesthetics plans to bring Merz' commercially successful line of injectable HA (hyaluronic acid) dermal fillers, called Belotero(R) to the US, once approved for marketing by the United States Food and Drug Administration (FDA). Belotero products are manufactured using a unique production process called Cohesive Polydensified Matrix (CPM) technology. This makes Belotero the world's first cohesive polydensified monophasic dermal filler. Merz hopes to introduce Belotero dermal fillers to the US market in early 2010, pending completion of clinical trials and following approval by the FDA.


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SOURCE Merz Pharmaceuticals USA
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