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Mental vulnerability associated with increased risk of cardiovascular disease
Date:4/17/2013

Rome, 18 April 2013. People deemed to be "mentally vulnerable" are at a significantly increased risk of both fatal and non-fatal cardiovascular disease, according to results of a large population study from Denmark. The details of the study were presented today at the EuroPRevent 2013 congress in Rome. (1)

The study's first author, Dr Anders Borglykke from the Research Centre for Prevention and Health
 at Glostrup University Hospital, Denmark, explained that psychosocial factors and personality traits have been consistently associated with cardiovascular disease and all-cause mortality, but their role in the prediction of risk was still not clear. This study was to investigate whether mental vulnerability (defined as "a tendency to experience psychosomatic symptoms or inadequate interpersonal reactions") increases the risk of cardiovascular disease and the precision of prediction models for cardiovascular disease.

The study incorporated data from three prospective Danish population cohorts from which almost 11,000 individuals free of any cardiovascular disease were followed-up for a mean period of 15.9 years (a total of 166,787 person-years). During this follow-up period all cardiovascular events (fatal and non-fatal) were recorded and, at the outset of the study, mental vulnerability measured on a validated 12-point scale originally constructed by the Military Psychology Services in Denmark. The results categorised subjects into three groups: "non-vulnerable, latent or mentally vulnerable".

"The scale consists of questions on both mental and physical symptoms," said Dr Borglykke, "and generally measures a level of stress or a personality which is more receptive to stress. The scale has previously been found associated with early mortality and ischaemic heart disease."(2) To assess the predictive ability of the scale, the results were added to a statistical model with classical risk factors for cardiovascular disease (age, sex
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Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3

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