Navigation Links
Mental Test Spots Alzheimer's Risk
Date:7/1/2008

Questionnaire for those close to patient pinpointed who was likely to progress to dementia

TUESDAY, July 1 (HealthDay News) -- A new questionnaire may help in both diagnosing older adults facing dementia and also in identifying individuals who need help with daily living.

The Everyday Cognition instrument consists of 39 questions to be answered by people who know the patient well.

"There have been a number of studies that show that people with mild cognitive impairment who have functional problems in addition to performing poorly on neuropsychological testing are more likely to progress in the near future," said study author Sarah Tomaszewski Farias, an assistant professor of neurology at the University of California, Davis, Medical Center in Sacramento. "One of our hopes is that this instrument will be able to help identify very early on those people at increased risk for developing Alzheimer's disease."

That would help both patients and family members prepare for what lies ahead and identify patients who need to be more closely monitored.

In addition, Farias said, the test would also help identify "people who are having [functional] problems so that we know who needs help and who doesn't."

"What's nice about this is that it is designed to pick up very early memory problems, and it's an entirely caregiver-based survey," said Dr. Scott Turner, incoming director of the Memory Disorders Program at Georgetown University Medical Center, in Washington, D.C. "This is something the caregiver can fill out, while the practitioner is looking at the patient. It could be used for screening, for diagnosis and for drug development, if you want to look for some proof that your drug is having some effect, so it has a lot of potential uses."

"They want something that they could use to ask a family member about the potential patient's everyday functioning to see if that's sensitive to picking up the likelihood of dementia early on," added Dr. Gary J. Kennedy, director of geriatric psychiatry at Montefiore Medical Center in New York City.

The findings were published in the July issue of Neuropsychology.

Existing neuropsychological tests tend to be very abstract. For the last 40 years, these tests have looked at two categories: so-called "basic" activities (such as grooming, feeding, dressing), which are affected in later stages of dementia, and "instrumental" activities of daily living (such as managing medication, finances, cooking, driving).

"I was interested in understanding how our neuropsychology tests translated into everyday problems, how our cognitive tests . . . translate into everyday problems that a person is experiencing and that a caregiver is concerned about," Farias explained.

Farias and her colleagues divided everyday functioning into seven cognitive "domains:" memory, language, semantic or factual knowledge, visual and spatial abilities, planning, organization and divided attention.

An original list of 138 items was eventually culled to 39, which was then tested in 576 older adults: 174 of whom were cognitively normal, 126 who had mild cognitive impairment (MCI), and 276 who had been diagnosed with dementia.

"Informants" (people who had known the patient for an average of almost 45 years) provided details on whether the patient could remember shopping items without a list, reading a map, balancing the checkbook, and cooking or working and talking at the same time.

Not only did the instrument confirm established diagnoses, it was also able to distinguish people with MCI from those with full-blown dementia, meaning it was able to pick up on subtle differences in function.

The results also weren't highly influenced by occupation and education levels, as are existing tests.

"This is really the first step in development the instrument," Farias said. "What we're really interested in doing is to track people over time to get a better understanding of the early signs of functional impairment."

More information

Visit the Alzheimer's Association for more on this condition.



SOURCES: Sarah Tomaszewski Farias, Ph.D., assistant professor, neurology, University of California, Davis, Medical Center, Sacramento; Gary J. Kennedy, M.D., director, geriatric psychiatry, Montefiore Medical Center, New York City; Scott Turner, M.D., incoming director, Memory Disorders Program, Georgetown University Medical Center, Washington, D.C.; July 2008, Neuropsychology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Justice Department Reaches Settlement to Improve Conditions at a Nebraska Developmental Center
2. NYU, Rutgers study shows how using mental strategies can alter the brains reward circuitry
3. Homosexual behavior due to genetics and environmental factors
4. Combined Insurance: Consider Supplemental Accident Insurance and Disability Insurance During Safety Awareness Month
5. Mental and physical exercise improves genetic mental impairment
6. Experimental Drug Fights Multiple Sclerosis Activity
7. Premier Web Site on Child and Teen Mental Health Now in Spanish
8. Experimental Therapy Beats Back One Patients Melanoma
9. Psych Central Selected by TIME Magazine as Top 50 Web Site in 2008 for Its Top Mental Health Content and Social Media Platform
10. Penn researchers find key developmental pathway activates lung stem cells
11. New York City Department of Health & Mental Hygiene Awards 2 Million Unit Bid to The Female Health Company
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mental Test Spots Alzheimer's Risk
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm ... sciences executive with extensive sequencing and genomics experience, as Vice President of North American ... Hill will be responsible for leading the sales team in the commercialization of the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
Breaking Medicine Technology: