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Menopausal Women May Have an Increased Asthma Risk, From The Journal of Allergy and Clinical Immunology

MILWAUKEE, Dec. 19 /PRNewswire/ -- Menopause is associated with lower lung function and more respiratory symptoms, especially among lean women, according to a new study in the Journal of Allergy and Clinical Immunology (JACI).

The study, "Lung function, respiratory symptoms, and the menopausal transition," can be found in the articles in press section of the JACI Web site, The JACI is the peer-reviewed journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

Francisco Gomez Real, MD, and colleagues studied a group of women aged 45-56 years who were not taking sex hormones. The women provided information about their lung health and menstrual history and the ratio of height to weight, body mass index (BMI).
The researchers found:

-- Women who had stopped menstruating had significantly lower lung

function and more respiratory symptoms than women of the same age who

were menstruating regularly.

-- Lean women (BMIs of less than 23 kg/m squared) showed a greater risk

for lung problems.

The authors speculate that lower lung function in menopausal women could be explained by increased insulin resistance in menopause. Furthermore, because insulin resistance is a proinflammatory condition, this could also explain the increase in respiratory symptoms associated with menopause.

Clinicians should be aware of increased asthma risk and lower lung function in women, especially lean women, reaching menopause.

The AAAAI represents allergists, asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic disease. Allergy/immunology specialists are pediatric or internal medicine physicians who have elected an additional two years of training to become specialized in the treatment of asthma, allergy and immunologic disease. Established in 1943, the AAAAI has more than 6,500 members in the United States, Canada and 60 other countries. The AAAAI serves as an advocate to the public by providing educational information through its Web site at

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