Dallas, Texas (PRWEB) May 24, 2013
This report “EpiCast Report: Meningococcal Disease - Epidemiology Forecast to 2022” provides an overview of the risk factors and global trends for meningococcal disease in eight major markets (8MM) (US, France, Germany, Italy, Spain, UK, Australia, and Brazil). It includes a 10-year epidemiological forecast of incident cases of meningococcal disease segmented by age (<1, 1–4, 5–14, 15–24, 25–44, 45–64, and =65 years) and serogroup (B, C, Y, and W-135) in these markets. The other serogroups, namely serogroups A and X, are not covered in this analysis because they have very low prevalence in the 8MM and because little data are available for these serogroups. Germany is the only country that had data available for serogroup A, and therefore serogroup A is included in this analysis for Germany. Due to the low incidence of meningococcal disease in Japan, this market was not included in the forecast.
Meningococcal disease is caused by Neisseria meningitidis, which is an encapsulated, Gram-negative bacterium that has an incidence of one to three cases per 100,000 population worldwide (Giuliani et al., 2006). Strains of Neisseria meningitidis are classified based on the chemical composition of unique polysaccharide capsules. Although there are 13 different serogroups, nearly all disease in humans is caused by strains representative of six serogroups: A, B, C, W-135, X and Y (CDC, 2012d; Halperin et al., 2012; Rosenstein et al., 2001). Humans are the only natural reservoir of Neisseria meningitidis, and the bacterium causes three common clinical forms of meningococcal disease: meningitis, blood infection, and pneumonia (CDC, 2012d; Wilder-Smith and Memish, 2003). Up to 10% of adolescents and adults are asymptomatic, transient carriers of the bacterium, which can be transmitted via respiratory droplets or by direct contact (CDC, 2012d).
This report provides an overview of the risk facto
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