Navigation Links
Meningitis vaccine study gets £200,000 boost
Date:2/7/2008

It can kill in four hours and more than 300 people in the UK die from it every year and hundreds more are left with permanent disabilities. Now researchers will work on a potential vaccine for meningitis B, thanks to a 200,000 grant from the medical charity Meningitis UK.

Although vaccines exist to protect against some strains of meningitis, there is still no vaccine to protect against all strains, including the most common in the UK Group B meningococci. This is responsible for almost 90 per cent of all cases and is most common in children under the age of five.

The team, led by Dr Karl Wooldridge, a lecturer in the Centre for Biomolecular Sciences, aim to develop a vaccine against this strain of the bacterium. Group B meningococci mimic molecules in the human body, which makes developing an effective vaccine against this strain very difficult.

Researchers worldwide are searching for alternative antigens molecules that can stimulate an immune response on the surface of the bacteria, which could be used as a basis for a vaccine against meningitis B.

The team has identified a series of autotransporter proteins proteins which are secreted from the surface of Group B meningococci which could be used to create antibodies that will then kill the bacteria.

The grant will be used to fund a two-year research post, examining each of the proteins produced by the bacteria for the potential to create effective antibodies. The genetic code for each protein will be cloned and tagged, allowing the protein to be produced in large amounts and purified for further study.

If we identify one or more of these proteins that give a good protective response we would ultimately move to human trials, said Dr Wooldridge. This would hopefully demonstrate a positive immune response to the vaccine. By identifying a range of active proteins, rather than just one, we could develop a vaccine that targeted all strains of the Group B
'/>"/>

Contact: Karl Wooldridge
karl.wooldridge@nottingham.ac.uk
University of Nottingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Schedules Revised for Flu, Meningitis Vaccines
2. New Meningitis Vaccine Works in Infants
3. Steroid Fails to Ease Meningitis in Trials
4. Meningitis Shot Available, Effective Year-Round
5. Tattooing Best Way to Deliver DNA Vaccines
6. Novel molecules developed at UB can boost vaccine potency
7. USDA Agrees to Grant Conditional License to Bioniche for its E. coli O157:H7 Cattle Vaccine
8. Another Study Finds No Link Between MMR Vaccine and Autism
9. New hospital standards needed for pediatric flu vaccines
10. Experimental Vaccine Halts Prostate Cancer in Mice
11. Novel vaccine concept developed by scientists at the Wistar Institute
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Older people become more physically vulnerable during bereavement, new ... hormones during bereavement changes with age, British researchers say. ... more likely to have weakened immune systems and develop ... and months after loss, we can suffer from reduced ... white blood cell and as such are essential at ...
(Date:9/18/2014)... PRAIRIE, Texas (PRWEB) September 18, 2014 ... for the air medical transport industry, ShandsCair Flight ... Airbus Helicopters Inc . (AHI) at the Air ... , The recently delivered and placed into service ShandsCair ... B4 that will be displayed at AMTC highlight Airbus ...
(Date:9/18/2014)... News) -- Daily supplements of selenium or vitamin E ... age-related cataracts among men, a new study indicates. ... could help prevent cataracts. To investigate this further, William ... School in Boston, and his colleagues examined data from ... The trial was initially designed to study prevention of ...
(Date:9/18/2014)... 18, 2014 Thousands of college and ... their shared fundraising impact on 127 member Children’s ... The first-ever Dance Marathon Day will officially kick off ... to be raised by college and high school students ... generated through Dance Marathon campus programs help provide medical ...
(Date:9/18/2014)... developed a new method to study Ebola virus in ... Conservation Society (WCS)-led research, published today in the journal ... of fecal samples from wild great apes to identify ... This represents a new tool for performing large, population-scale ... virus is studied and improve our understanding of the ...
Breaking Medicine News(10 mins):Health News:Grief Can Weigh on Immune System in Older Folks, Study Says 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 3Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 4Health News:Vitamin E, Selenium Supplements Don't Seem to Prevent Cataracts 2Health News:250 Campuses Usher in School Year of Saving Kids’ Lives During First-Ever “Dance Marathon Day” on Sept. 25 2Health News:Research yields a game changer for improving understanding of Ebola and great apes 2Health News:Research yields a game changer for improving understanding of Ebola and great apes 3
... discovered a new signaling molecule that prevents immune responses ... could lead to the development of new treatments for ... 1 diabetes; and for inflammatory diseases, such as inflammatory ... Jude team discovered that specialized immune lymphocytes called regulatory ...
... Inc. (NYSE: VAR ), a premier supplier of X-ray tubes ... new,PaxScan products at the annual meeting of the Radiological Society of ... 30, 2007., -- The PaxScan 4336R adds a 14 ... of flat panel products. It is specifically designed to ...
... 21 The following release and,statements are attributed ... a nonprofit organization dedicated to raising awareness,and improving ... Americans with liver,disease, issued a statement today expressing ... physician Dr. Harvey Finkelstein made repeated,use of medicine ...
... CHICAGO --- When you meet your boss,s husband, Harvey, at ... later over the onion dip, will you remember his name? ... brain called kalirin-7. , Researchers at ... protein kalirin is critical for helping you learn and remember ...
... Nov. 21 The Advisory Board,Company (Nasdaq: ABCO ... CIBC,World Markets Third Annual Mid & Small Cap ,Best ... York City. Speaking at the conference,on November 28th, 2007 ... Chief Executive Officer, Frank J. Williams, and the Company,s ...
... Komen for the Cure, the,nation,s largest private source ... programs, is accepting applications to award,four-year undergraduate scholarships ... cancer., (Logo: http://www.newscom.com/cgi-bin/prnh/20070122/NYM084LOGO ), The ... costs of,tuition, books, fees and on-campus room and ...
Cached Medicine News:Health News:St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases 2Health News:St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases 3Health News:Varian Medical Systems to Introduce Two New PaxScan(R) Flat-Panel Digital Radiography Products at RSNA This Year 2Health News:Varian Medical Systems to Introduce Two New PaxScan(R) Flat-Panel Digital Radiography Products at RSNA This Year 3Health News:The American Liver Foundation Encourages Heightened Awareness of Hepatitis B and C in Light of Recent Events in the News 2Health News:Why you remember names and ski slopes 2Health News:Susan G. Komen for the Cure Provides Scholarships for Students Who Lost a Parent to Breast Cancer 2
(Date:9/18/2014)... , Sept. 18, 2014  Low T ... committee meeting in Hyattsville, Maryland ... to assess the proper patient population for testosterone ... cardiovascular risk associated with TRT. Examining recent claims from ... found that "available epidemiological studies do not provide ...
(Date:9/18/2014)... , Sept. 18, 2014  Aratana Therapeutics, ... therapeutics company focused on licensing, developing and commercializing ... the full exercise of the underwriters, option to ... connection with the company,s previously announced public offering ... the shares are being offered by Aratana Therapeutics.  ...
(Date:9/18/2014)... 18, 2014 ... has announced the addition of the  "Sugar ... to their offering.       (Logo: ... markets for Sugar Alcohols in Million Pounds ... Confectionery, Pharmaceuticals, Cosmetics, Oral-Care Products, and Others.  ...
Breaking Medicine Technology:Low T Center Endorses The Joint FDA Committee Meeting on Testosterone 2Aratana Therapeutics, Inc. Announces Full Exercise of Underwriters' Option to Purchase Additional Shares 2Sugar Alcohols - Global Strategic Business Report 201 2Sugar Alcohols - Global Strategic Business Report 201 3
... of the premier providers of innovative supplies for continuous ... of its fifth year with a variety of planned ... the high-quality standards and innovation that the home health ... Circadiance has its sights set on being ...
... Jan. 13, 2012 IBM (NYSE: IBM ) ... made from silicon that can aid researchers and ... drug discovery and disease diagnostics. ... Tissue staining is widely used in pathology to ...
Cached Medicine Technology:Circadiance to Launch New Respiratory Supply Products 2MADE IN IBM LABS: New Silicon Probe Assists in Disease Diagnostics and Drug Discovery 2MADE IN IBM LABS: New Silicon Probe Assists in Disease Diagnostics and Drug Discovery 3MADE IN IBM LABS: New Silicon Probe Assists in Disease Diagnostics and Drug Discovery 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: