Navigation Links
Men who are continually active at work may have a decreased risk of prostate cancer
Date:2/12/2008

Men with jobs that require them to be physically active may be getting benefits beyond salary and health insurance - they may be at a decreased risk of developing prostate cancer, according to a study at UCLAs Jonsson Cancer Center.

Researchers studied more than 2,100 men who worked at the Rocketdyne facility in the San Fernando Valley, many of whom were exposed to radiation and chemicals that may have increased their risk for certain cancers. The research team identified 362 men who developed prostate cancer and compared them to 1,805 men of similar age and socioeconomic status who did not get prostate cancer.

The study, done in conjunction with researchers at the Olive View-UCLA Education and Research Institute and the University of Michigan, appears in the February issue of the journal Cancer Causes Control.

The message from this study for today is that if youre more active, you may be able to prevent this cancer from happening, said Beate Ritz, a Jonsson Cancer Center researcher, an associate professor of epidemiology in the UCLA School of Public Health and the studys senior author. If you have a desk job, do something physically active to counterbalance it. The case-control study nested within a larger cohort of more than 10,000 subjects focused on men who worked at the nuclear and rocket engine testing facility from the 1950s to the early 1990s. The cases of prostate cancer were diagnosed between January 1988 and December 1999. Researchers obtained cancer incidence data for the workers from the California Cancer Registry and seven other cancer registries in neighboring states where workers may have moved after retirement.

Data from Rocketdyne company records was used to construct a job exposure matrix that ranked job descriptions by the amount of physical activity required and any harmful exposures the workers might have experienced.

Physical activity was separated into jobs with low, moderate and high amounts of exertion. Men with low physical activity jobs were typically managers, supervisors, analysts, administrators and senior engineers. Those with moderately physically active jobs included senior mechanics and technicians, inspectors and engineers. Masons and bricklayers, metal fitters, welders, packers, painters, tool and die makers, truck drivers, lift operators and janitors were considered to have highly physically active jobs.

The study found that the men who developed prostate cancer were less likely to hold the more physically active jobs. Those that got cancer also were more likely than the control group to be highly exposed to the chemicals that were evaluated, including hydrazine, benzene, mineral oil, polycyclic aromatic hydrocarbons (PAHs) and trichloroethylene (TCE), which are known or suspected carcinogens.

The findings are supported by other studies that suggest continuous physical activity, but not intermittent activity, is required to lower the risk of prostate cancer. The biologic mechanisms by which physical activity lower prostate cancer risk have not been identified, although some experts have speculated that activity can alter hormone levels in some men.

A strength of the UCLA study was that researchers used personnel records, job description manuals, industrial hygiene review and retired worker interviews to develop their job exposure matrix, avoiding problems with study subject recall and interviewer bias. Researchers also were able to obtain cancer incidence data and did not have to rely on mortality data. Prostate cancer is largely non-fatal, so mortality rates would not have been good data to analyze, Ritz said.

The study was limited in that researchers were not able to account for other potential factors that might affect prostate cancer risk, such as recreational physical activity and diet, said Anusha Krishnadasan, an epidemiologist at Olive View-UCLA Education and Research Institute and first author of the study.

All we can say for sure is that aerospace workers that were highly active on a regular basis for many years while working at Rocketdyne were at a decreased risk of prostate cancer, she said.

In a subset of subjects, researchers found that the men who developed prostate cancer were more likely to have a family history of the disease, to be African American and report having participated in routine screening for prostate cancer.


'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. Many Older Americans Have Active Sex Lives
2. More than two-thirds of sexually active NYC youth use condoms, but other forms of birth control lag
3. Schwablearning.Org Launches Interactive Tool to Help Parents of Children Struggling in School
4. Human C-reactive protein regulates myeloma tumor cell growth and survival
5. National Movement Disorders Interactive Experience Center Comes to Tampa Bay for First Time
6. Figure Skater Peggy Fleming Teams with HealthSaver: Raise Healthy Children Through Active Parenting
7. A New Interactive Consumer Experience Highlighting Successful Weight Loss Strategies is Coming to a Mall Near You
8. PDL BioPharma to Actively Seek Sale of Entire Company or Its Key Assets
9. Strawberry Consumption Associated with C-Reactive Protein Among Women: New Harvard Study
10. Mayo Clinic Proceedings: Men with chronic heart failure can have active sex lives
11. Inside job: new radioactive agents for colon cancer work inside cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... , ... December 02, 2016 , ... ... of "Cardiovascular Health" in USA Today, which covers the innovative treatments, therapeutic technologies, ... while maintaining fulfilling lives. “We are prolonging life 6 years in the last ...
(Date:12/2/2016)... NJ (PRWEB) , ... December 02, 2016 , ... Sourced ... Water has some unique properties including its unmatched natural purity of just 6 ppm ... clean and crisp. , Nothing Water has been available in several ShopRite and FoodTown ...
(Date:12/2/2016)... San Francisco, CA (PRWEB) , ... December 02, ... ... in digitally-enabled care journeys, announced today that it has raised $6.0 million in ... are inspired by Clarify Health’s conviction that patients and their caregivers can receive ...
(Date:12/2/2016)... ... 2016 , ... ‘Tis the season for giving! Today, 20 creative teams across ... Partnership and the Drug Enforcement Administration as part of the National Red Ribbon Week ... schools who decorated their campuses with this year’s Red Ribbon Week theme: “YOLO. Be ...
(Date:11/30/2016)... ... November 30, 2016 , ... Standard Process, ... an annual ranking and recognition of the largest closely held companies headquartered in ... from 2008-2016. In addition, Standard Process was awarded the Talent Award for providing ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Dec. 2, 2016 Quantum Radiology,s Mobile Breast ... radiologist interpretation directly to women at the workplace, thereby ... such as Delta Air Lines and SunTrust Bank, and ... a component of wellness initiatives. "I think ... It enables them to have a mammogram without taking ...
(Date:12/2/2016)... , Dec. 2, 2016  Eli Lilly and Company ... guidance for 2017 and provide updated financial guidance for ... conduct a conference call on that day with the ... financial guidance. The conference call will begin ... public can access a live webcast of the conference ...
(Date:12/2/2016)... , December 2, 2016 Orthopedic ... & Support) is Expected to Gain a Significant Market Share ... Orthopedic Ailments  ... , According to a ... on Medical Implants Sterile Packaging: Clamshell Product Type Segment Projected ...
Breaking Medicine Technology: