Navigation Links
Memory tasks require more coordinated brain blood flow for people with high blood pressure
Date:9/27/2007

Blood flow to the parts of the brain that support memory function differs between people with high blood pressure and those with normal blood pressure, and this difference seems to increase when high blood pressure is treated with medications, researchers reported today at the American Heart Associations 61st Annual Fall Conference of the Council for High Blood Pressure Research.

It does not mean that those with high blood pressure were remembering significantly less; rather, the brain areas acting together during memory required more blood flow to remember the same things as people who did not have high blood pressure in the study, said lead author J. Richard Jennings, Ph.D.

In a previous study, Jennings and colleagues found that people with hypertension differed from those without hypertension in the amount of brain tissue activated during memory tasks.

In this study we wanted to find out if treating people for high blood pressure would change that pattern of activation, said Jennings, a professor of psychiatry and psychology at the University of Pittsburgh School of Medicine in Pittsburgh, Pa.

The researchers assessed the brain blood flow of 28 adults with untreated hypertension while they were doing a memory task. The researchers then randomly divided the subjects into two hypertension treatment groups. Half received the angiotension-converting enzyme inhibitor lisinopril; the other half received the beta-blocker atenolol. Subjects took the medication for a year before researchers tested them in the same way, again monitoring their blood flow to the brain as they did the memory task.

Jennings and colleagues were surprised to find that taking either antihypertensive medication actually increased the inefficiency of the brains work during memory. He explained that, when doing memory tasks, four areas of the brain become active in different ways: the thalamus, posterior parietal, prefrontal area and hippocampus.

In the first study, we looked at the correlation between the activation of those areas. We wanted to see if the areas tend to be activated in a correlated way; so, if you had a lot of activation in the prefrontal area, did you also have a lot of activation in the parietal area" he said. When we asked that question in our first study, we found out that the correlation in those areas was higher in people with high blood pressure than it was in people who didnt have high blood pressure. That means that more brain tissue was getting coordinated during the memory task in people with high blood pressure than in those with normal blood pressure.

After a year of treatment for their high blood pressure, we expected that wed find that the correlation between those areas actually would decrease; so, the patients treated with hypertensive medication would look more like those with normal blood pressure. Instead, the correlation actually increased. After treatment the hypertensive patients were activating even more blood flow to those areas at the same time, Jennings said.

According to Jennings, the coordination between brain areas doing the memory task was more than twice as much in the hypertensive patients after treatment as compared to before treatmentand this difference was even bigger compared to people without hypertension.

Further research is needed to find out what this means to memory function, and whether having hypertension and taking antihypertensives might have the unanticipated effects of changing brain function and causing mental fatigue, he said.

This research is reassuring to those concerned about hypertension therapys adverse effects, particularly cognitive effects. Treating hypertension is not only beneficial for extending life, but also for improving the quality of life, said Daniel W. Jones, M.D., American Heart Association President, Vice Chancellor for Health Affairs, Dean, School of Medicine, and Herbert G. Langford Professor of Medicine, University of Mississippi Medical Center.


'/>"/>

Contact: Karen Astle
karen.astle@heart.org
214-706-1392
American Heart Association
Source:Eurekalert

Related medicine news :

1. Brisk Walking lowers memory loss in women
2. Memory said to automatically improve with age
3. And now its super mice for longer memory
4. Memory problem? solve a crossword
5. Is there a link between bones and memory?
6. Deep Sleep Doesnt Increase Memory
7. Breakfast improves memory
8. For a Better Memory
9. Left handed have better episodic memory
10. Coffee enhances memory
11. Protein and fat improve memory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Guerbet announced today that it has been named a ... One of 12 suppliers to receive the ... of Premier members through exceptional local customer service and ... lower costs. "We ... customer service from Premier," says Massimo Carrara , ...
(Date:6/23/2016)... June 23, 2016 Research and ... Procedure Volumes: Global Analysis (United States, China, Japan, Brazil, ... report to their offering. ... for healthcare business planners, provides surgical procedure volume data ... trends with an in-depth analysis of growth drivers and ...
(Date:6/23/2016)... The Biotechnology industry might still ... great opportunities to investors. Stock-Callers.com assesses the recent performances ... XON ), Vertex Pharmaceuticals Inc. (NASDAQ: ... ARNA ), and Regeneron Pharmaceuticals Inc. (NASDAQ: ... your complimentary trade alerts at: http://stock-callers.com/registration ...
Breaking Medicine Technology: