Navigation Links
Memory problems not the only predictor of later mild cognitive impairment
Date:6/28/2010

Mild cognitive impairment is often seen as a transition stage between the cognitive decline of normal aging and the more serious problems of Alzheimer's disease. But what leads to mild cognitive impairment?

Researchers at Rush University Medical Center have found that lower, though not necessarily impaired, performance on tests measuring story learning or retention and processing speed in motor tasks dependent on visual control, as well as symptoms of depression, predicted subsequent cognitive decline in a normal population.

None of the factors alone predicted the onset of mild cognitive impairment a year later. Rather, poor learning had to be accompanied by either slower visuomotor processing speed or depressive symptoms to be significantly related to later problems in cognition.

Using an advanced statistical methodology that analyzed multiple variables at once, the researchers also found that neither gender nor the apolipoprotein E genotypelong believed to be risk factors for mild cognitive impairmenthad any substantial influence on later impairment.

The study is published in the July issue of the Journal of the International Neuropsychological Society.

"For a long time, researchers believed that memory alone was the only important factor in mild cognitive impairment," said Dr. S. Duke Han, assistant professor of neuropsychology in the Department of Behavioral Sciences at Rush and lead author on the study. "Our study is one of the first to suggest the importance of other factors in predicting this possible pre-Alzheimer's condition."

The 94 individuals who participated in the study underwent a battery of standard cognitive and psychosocial tests to assess mood, attention, visuospatial abilities, language facility, memory and intelligence. These included the Trail-Making Test, which measures motor speed, visual attention, and cognitive flexibility; the Wisconsin Card Sorting Test, which measures the ability to problem solve; a delayed recall test; the American National Adult Reading Test; and the Geriatric Depression Scale. Information was collected on age, education, gender and genotype.

Lower performance on tests measuring learning, when paired with either slower speed on the Trail-Making Test or a lower score on the depression scale, predicted the development of mild cognitive impairment a year later with an accuracy of 80 to 100 percent in the test sample.


'/>"/>

Contact: Sharon Butler
Sharon_Butler@rush.edu
312-942-7816
Rush University Medical Center
Source:Eurekalert

Related medicine news :

1. Memory Loss Supplement Manufacturer Partners With Nationally-Syndicated Radio Host John Tesh
2. To Boost Your Memory, Take a Break
3. Immune memory formation seen in early stages of viral infection
4. Brain scientists extend map of fear memory formation
5. Discovery of epigenetic memory during breast cancer
6. Study shows link between working memory and reactive parenting
7. InfoZoom Launches V6.4 of its Industry Leading In-Memory Data Analysis Software
8. Healthy older adults with subjective memory loss may be at increased risk for MCI and dementia
9. €1.6 million ($2.32 million) grant awarded to Prof. Kobi Rosenblum for brain and memory research
10. The Run for the Memory Marathon Team Getting in Shape and Fighting Alzheimers
11. Bioethics memory aid can help assess patient decision-making capacity in medical emergencies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2017)... OH (PRWEB) , ... February 19, 2017 , ... Braun ... The JEMS Conference & Exposition, the event will take place February 23-25, 2017 at ... Industries will be in Booth #909 with three new ambulances on display. ...
(Date:2/19/2017)... ... February 19, 2017 , ... ... home healthcare, will join forces with Healthwise ® at HIMSS 2017 ... the industry leader in evidence-based health education, technology and services, will demonstrate a ...
(Date:2/18/2017)... ... ... Butler Mobility invited Ken Matthews to visit its manufacturing facility and showroom ... impressed with the safety and reliability of the Stannah Stairlift as well as with ... endorsement by Ken Matthews can be heard on News Radio WHP 580 weekdays from ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph Fashion Volume 2 ... ’ ProParagraph Fashion Volume 2 for all multi-line FCPX project needs. Great ... pick and choose from hand-crafted trend-setting designs with smooth animations that will add ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... kept pace. Enovate Medical has introduced an innovative workstation designed to reduce nursing ... nurses, the Encore Mobile EHR Workstation offers a lightweight, highly mobile, multi-functional alternative ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... According to a new market research report "Particle Counters Market ... Contamination Monitoring of Liquids), and End User (Healthcare Industry, Semiconductor Industry) ... expected to reach USD 330.6 Million by 2021 from USD 275.9 ... 2021. Continue Reading ... ...
(Date:2/17/2017)... , Feb. 17, 2017 Theravance ... Biopharma" or the "Company") today announced the presentation ... potent, and orally administered pan-Janus kinase (JAK) inhibitor ... th Congress of the European Crohn,s and ... Company reported further data from its completed Phase ...
(Date:2/17/2017)... -- Research and Markets has announced the addition of the ... their offering. ... separate comprehensive analytics for the US, Canada , ... , and Rest of World. Annual estimates and forecasts are provided ... provided for these markets. Market data and analytics are derived from primary ...
Breaking Medicine Technology: