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Memories That Make Your Heart Race Can Be Defanged
Date:12/9/2009

Discovery may help people with anxiety or post-traumatic stress disorder

WEDNESDAY, Dec. 9 (HealthDay News) -- A new study suggests that people might be able to reduce the power of fearful memories that cause physical symptoms when they're triggered.

The research is preliminary, and study co-author Elizabeth Phelps cautioned that it doesn't provide an immediate cure for such conditions as anxiety and post-traumatic stress disorder. But it does offer some hope for new ways to treat them in the future, said Phelps, who directs a laboratory at New York University's psychology department.

The key, she said, is to interfere with a memory "at a particular time when we know it may be vulnerable or susceptible to being changed."

The memories in question link an emotional fear to a physical response, she said.

For example, imagine you are bitten by the pit bull next door, and then you come across the dog again. You'll have a memory of the incident, Phelps said, but also possibly another kind of memory that will kick in a physical reaction.

"You'll start to tense up, sweat a little and your heart will race," she said. "That's the memory we're talking about."

This kind of "fear memory" is stored in a different part of the brain than the actual memory of the event that triggered it, she said.

In people with anxiety problems and post-traumatic stress disorder, such memories can lead to major trouble.

Phelps and her colleagues suspected that there are times when the memories are susceptible to influence. They tested their theories and report their findings in the Dec. 10 issue of Nature.

The researchers instilled fear memories in study participants by shocking them when they saw certain visual images. The idea was to make them develop a fear memory connected to the image and then see if they could undo it.

The researchers found that they could defang
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