Navigation Links
Memorial University Medical Center (MUMC) Implements PNA FISH(R) Tests to Help Provide Best Care for Patients with Bloodstream Infections

First hospital in Georgia to use a new, cutting edge diagnostic technology to fight serious infections and improve patient care and outcomes.

WOBURN, Mass., and VEDBAEK, Denmark, June 2 /PRNewswire/ -- AdvanDx today announced Memorial University Medical Center in Savannah, Georgia has implemented AdvanDx's PNA FISH(R) tests to identify bloodstream pathogens 1 to 3 days earlier than conventional methods to help their physicians, pharmacists and nurses improve care and outcomes for patients with bloodstream infections(1).

Every year, 350,000 patients contract bloodstream infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes. Conventional diagnostic methods can take 48 hours or longer forcing physicians to treat patients empirically with broad-spectrum antibiotics that may prove to be ineffective and can lead to long-term resistance.

AdvanDx's PNA FISH tests employ unique technology that detects bacteria's genetic material to provide identification results in just over 2 hours. "The fast tests will enable the microbiology lab to provide results 1 to 3 days sooner than conventional methods for such serious pathogens as Staphylococcus aureus, Candida albicans and Candida glabrata," said Vera Pagan, Microbiology Manager at Memorial University Medical Center.

Clinical trials conducted at hospitals in the United States have shown that implementing PNA FISH and delivering fast results to clinicians directed earlier, effective antibiotic therapy, reduced mortality rates and improved hospital operational efficiency by reducing hospital length of stay, bed utilization, and pharmacy and lab costs related to unnecessary antibiotic use(1,2,3). Memorial University Medical Center is the first hospital in southeast Georgia to implement the rapid PNA FISH tests.

"We are very excited to implement the latest diagnostic tool to help our clinicians identify these serious infections in our critically ill patients," said. Richard S. Roth, M.D., infectious disease physician at Savannah Infectious Disease, who along with Jason Lin, Pharm.D., Clinical Infectious Diseases Pharmacist at Memorial University Medical Center are championing the clinical implementation of using rapid microbiology results to guide therapy. "The fast results from the laboratory will enable our clinicians to know which pathogens they are dealing with much earlier, will help them prescribe the most appropriate antibiotic, and allow us to deliver the best care for our patients," Dr. Roth added.

About Memorial Health

Memorial Health is a two-state healthcare organization serving a 35-county area in southeast Georgia and southern South Carolina. The system includes its flagship hospital, a 530-bed academic medical center; Memorial primary and specialty care physician networks; a major medical education program; business and industry services; and NurseOne, a 24-hour call center.

About Bloodstream Infections

Every year, 350,000 patients contract bloodstream infections, causing over 90,000 unnecessary deaths and significant costs to the healthcare system. The infection is detected when a culture of the patient's blood (i.e. a blood culture) turns positive with bacteria and yeast. Rapid and accurate identification of the specific infecting pathogen is crucial to ensure early and appropriate therapy and save patient lives.


PNA FISH is an easy-to-use and highly sensitive and specific fluorescence in situ hybridization (FISH) assay that uses PNA (peptide nucleic acid) probes to target species specific ribosomal RNA (rRNA) in live bacteria and yeast. PNA FISH tests enable microbiology labs to provide rapid and accurate identification of bloodstream pathogens directly from positive blood cultures in hours instead of days. Clinical studies show that rapid identification of bloodstream pathogens using PNA FISH tests leads to more appropriate patient therapy that saves lives and reduces unnecessary antibiotic use, patient length of stay and hospital costs.

    (1)Forrest et al.  Antimicrob Agents Chemother. 2008 Oct;52(10):3558-63.
    (2) Shoham et al. Ther Clin Risk Manag. 2008 Jun;4(3):637-40.
    (3) Forrest et al. J Antimicrob Chemother. 2006 Jul;58(1):154-8.


Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. William W. Wirtz Allocates $19.5 Million to Northwestern Memorial for Cancer Care and Research
2. The Healthcare Scoop Encourages Sun Safety This Memorial Day Weekend And Into Summer
3. Franklin Memorial Hospital Thrives on the InstaMed Network
4. Top 10 Pet Travel Tips for Memorial Day
5. Haiti Hosts Opening Ceremony of the 2009 International AIDS Candlelight Memorial: Worldwide Events Commence With the Announcement of a National HIV Testing Campaign in Haiti
6. Full Calendar of Activities for 24th Los Angeles Marathon This Memorial Day Weekend
7. Thomson Reuters Honors Keystone Mercy and AmeriHealth Mercy Health Plans and Tallahassee Memorial HealthCare
8. Dunwoody Partners with North Memorial for Radiologic Technologist Program
9. MedGenix Financial Information System Selected by Bates County Memorial Hospital
10. YWCA USA Celebrates Sojourner Truth Memorial in U.S. Capitol
11. Smallest full support heart assist device on trial at Northwestern Memorial
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... Brenntag Specialties, Inc. (BSI) ... for the Nutraceutical Specialties products into oral solid dosage in the over the ... “We are pleased to announce our expanded distribution agreement with ASI.” said Steve ...
(Date:11/30/2015)... ... November 30, 2015 , ... An inventor from Charlottesville, Va., is ... "My last baby had high blood pressure due to loud noises," she said, "so ... babies from noise pollution as well as radio waves and microwaves." , The baby ...
(Date:11/30/2015)... ... November 30, 2015 , ... Since its ... specializing in independent living, assisted living and all other retirement options. Support for ... awareness and research remains a top priority. , So it’s no surprise ...
(Date:11/30/2015)... New York, New York (PRWEB) , ... November 30, 2015 , ... ... at the Greater New York Dental Meeting. Their Ecosystem empowers dentists to make complex ... Dentists who visit the booth will receive a free fee survey with 10 procedures ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... of DataTrade Solutions Inc., a Healthcare IT consulting, development and support company. The ... and technical experience available within DataTrade to extend the services currently provided by ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , Nov. 30, 2015   Nuance Communications, Inc. ... National Decision Support Company (NDSC) today jointly announced ... collaboration capabilities that utilize the American College of Radiology,s ... provider organizations to comply with current and emerging ... --> By combining clinical decision support, ...
(Date:11/30/2015)... , Nov. 30, 2015  Novartis will demonstrate the ... 57 th American Society of Hematology (ASH) Annual ... myelomas as well as supportive care, including key findings ... personalized cell therapies. The ASH Annual Meeting will be ... . Novartis Oncology . "We will be ...
(Date:11/30/2015)... Israel , Nov. 30, 2015  OticPharma, Ltd., ... and developing innovative therapies for ear, nose, and throat ... A. Katkin as chairman of the company,s board ... executive officer for OticPharma, Ltd.  "Keith brings a wealth ... will be able to share this experience and provide ...
Breaking Medicine Technology: