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Memantine and Alzheimer's disease
Date:1/10/2008

re importantly, its complex pharmacological profile requires careful considerations concerning suitable doses and suitable patient groups, so that the best use can be achieved for patients suffering from Alzheimers disease.

Lead investigator Dr. Bettina Platt, University of Aberdeen, Institute of Medical Sciences, commented, Clearly, the claim that memantines beneficial action is due to the reduction of glutamate signalling needs to be revised. It is highly unlikely that compounds directly targeting glutamate receptors will be successfully introduced into the clinic, since major side-effects must be expected.


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Contact: Astrid Engelen
a.engelen@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

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