Navigation Links
Melanomas may appear noticeably different than other moles
Date:1/21/2008

A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are ugly ducklings), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

Rates of malignant melanoma continue to increase, and early identification allows surgeons to treat the disease by removing the tumor, according to background information in the article. The disease is more common in individuals with many moles or other skin marks, especially if the marks are atypical in color, shape or size. The challenge for clinicians who diagnose and treat pigmented skin lesions is to distinguish between malignant melanoma and benign simulants, the authors write.

Alon Scope, M.D., of the Memorial Sloan-Kettering Cancer Center, New York, and colleagues obtained images of the backs of 12 patients from a database of standardized patient images. All of the patients had at least eight atypical moles, and five patients had one lesion that had been confirmed as a melanoma. Thirty-four study participantsincluding eight pigmented lesion experts, 13 general dermatologists, five dermatology nurses and eight non-clinical medical staffwere asked to evaluate the images and identify lesions that looked different from all other atypical moles.

All five melanomas and only three of 140 benign lesions (2.1 percent) were generally apparent as different, meaning that two-thirds of the participants identified them as ugly ducklings. The malignant melanomas were apparent as being different to at least 85 percent of participants, whereas the agreement rate on the benign lesions perceived as being different was 76 percent at most, the authors write. Four lesions were generally apparent as completely different, all four being malignant melanomas.

For all participants, the test had a sensitivity of 90 percent, meaning 90 percent of the melanomas were identified as different. Sensitivity was 100 percent for the pigmented lesion experts, 89 percent for general dermatologists, 88 percent for nurses and 85 percent for non-clinicians.

Although the sensitivity and specificity and diagnostic accuracy of the ugly duckling sign depended on clinical expertise, the values for these parameters were good in all subgroups of participants, the authors write. These preliminary findings suggest that the ugly duckling sign may prove to be a useful screening strategy for primary health care providers and even for skin self-examination.


'/>"/>

Contact: Jeanne D'Agostino
646-227-3573
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Oral osteoporosis meds appear to reduce the risk of jaw degradation
2. Testosterone supplementation for older men appears to have limited benefit
3. Receptor protein appears to be key in breakdown of kidney filtration
4. Robotic device appears useful for surgical removal of cancer involving the tonsils
5. Molecular pathway appears crucial in development of pulmonary fibrosis
6. Amsterdam Native and St. Jude Patient Christian Gizara to Appear With Marlo Thomas on Dec. 8 Larry King Live to Educate Viewers About Life-Saving Work of St. Jude Childrens Research Hospital(R)
7. Follow-up imaging of benign-appearing incidental adrenal masses is unnecessary
8. Amsterdam Native and St. Jude Patient Christian Gizara to Appear With Marlo Thomas on Nov. 30 Larry King Live to Educate Viewers About Life-Saving Work of St. Jude Childrens Research Hospital(R)
9. Huge numbers willing to go under knife to alter their appearance, study finds
10. MS that runs in families appears more severe than non-familial MS
11. Nourishment Is Essential to a Youthful Appearance. Time to Feed Your Face with Serum_G
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... ... 2017 , ... Anesthesia Progress – Everyone wants less pain during ... option for each patient. Dentists have several general anesthesia alternatives and finding the right ... the Tokyo Dental College in Tokyo, Japan wanted to find out which anesthetic was ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... Healthful-Flex. , The company, owned and operated by Ed Stroup, was created ... reasonable price with the highest level of customer service. Healthful Balance products can ...
(Date:1/17/2017)... Clemente, CA (PRWEB) , ... January 17, 2017 ... ... Diego County, as well as Palm Desert, is opening a new office in ... Brainsway deep transcranial magnetic stimulation (dTMS) in Southern California, successfully treating individuals struggling ...
(Date:1/17/2017)... ... 2017 , ... A prescription medication bottle, pocket knife, luggage and a solar-powered ... Product Design Challenge , the Cradle to Cradle Products Innovation Institute has ... scheduled to run through early 2018. The challenges are presented by the Institute in ...
(Date:1/17/2017)... CA (PRWEB) , ... January 17, 2017 , ... Livionex, ... the results of a double blind clinical study for its dental gel that shows ... leading national brand of toothpaste containing triclosan. The study was conducted at the Beckman ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... 17, 2017  Zimmer Biomet Holdings, Inc. (NYSE and ... today announced that it has implemented a ... the Zimmer Biomet management team. Effective January 23, ... the position of President, Americas and join the ... served as Zimmer Biomet,s Vice President of U.S. ...
(Date:1/17/2017)... Research and Markets has announced the addition of the ... ... laparotomy sponges market to grow at a CAGR of 7.94% during ... 2016-2020, has been prepared based on an in-depth market analysis with ... its growth prospects over the coming years. The report also includes ...
(Date:1/17/2017)... BELLEFONTE, Pa. , Jan. 17, 2017 /PRNewswire/ ... Medical, Inc.(AMI) announces the addition of 6 senior ... of the TubeClear® System.  These sales leaders were ... recently acquired medical device company. Repeatedly recognized for ... of exceeding customer expectations and establishing relationships with ...
Breaking Medicine Technology: