Navigation Links
Melanomas may appear noticeably different than other moles
Date:1/21/2008

A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are ugly ducklings), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

Rates of malignant melanoma continue to increase, and early identification allows surgeons to treat the disease by removing the tumor, according to background information in the article. The disease is more common in individuals with many moles or other skin marks, especially if the marks are atypical in color, shape or size. The challenge for clinicians who diagnose and treat pigmented skin lesions is to distinguish between malignant melanoma and benign simulants, the authors write.

Alon Scope, M.D., of the Memorial Sloan-Kettering Cancer Center, New York, and colleagues obtained images of the backs of 12 patients from a database of standardized patient images. All of the patients had at least eight atypical moles, and five patients had one lesion that had been confirmed as a melanoma. Thirty-four study participantsincluding eight pigmented lesion experts, 13 general dermatologists, five dermatology nurses and eight non-clinical medical staffwere asked to evaluate the images and identify lesions that looked different from all other atypical moles.

All five melanomas and only three of 140 benign lesions (2.1 percent) were generally apparent as different, meaning that two-thirds of the participants identified them as ugly ducklings. The malignant melanomas were apparent as being different to at least 85 percent of participants, whereas the agreement rate on the benign lesions perceived as being different was 76 percent at most, the authors write. Four lesions were generally apparent as completely different, all four being malignant melanomas.

For all participants, the test had a sensitivity of 90 percent, meaning 90 percent of the melanomas were identified as different. Sensitivity was 100 percent for the pigmented lesion experts, 89 percent for general dermatologists, 88 percent for nurses and 85 percent for non-clinicians.

Although the sensitivity and specificity and diagnostic accuracy of the ugly duckling sign depended on clinical expertise, the values for these parameters were good in all subgroups of participants, the authors write. These preliminary findings suggest that the ugly duckling sign may prove to be a useful screening strategy for primary health care providers and even for skin self-examination.


'/>"/>

Contact: Jeanne D'Agostino
646-227-3573
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Oral osteoporosis meds appear to reduce the risk of jaw degradation
2. Testosterone supplementation for older men appears to have limited benefit
3. Receptor protein appears to be key in breakdown of kidney filtration
4. Robotic device appears useful for surgical removal of cancer involving the tonsils
5. Molecular pathway appears crucial in development of pulmonary fibrosis
6. Amsterdam Native and St. Jude Patient Christian Gizara to Appear With Marlo Thomas on Dec. 8 Larry King Live to Educate Viewers About Life-Saving Work of St. Jude Childrens Research Hospital(R)
7. Follow-up imaging of benign-appearing incidental adrenal masses is unnecessary
8. Amsterdam Native and St. Jude Patient Christian Gizara to Appear With Marlo Thomas on Nov. 30 Larry King Live to Educate Viewers About Life-Saving Work of St. Jude Childrens Research Hospital(R)
9. Huge numbers willing to go under knife to alter their appearance, study finds
10. MS that runs in families appears more severe than non-familial MS
11. Nourishment Is Essential to a Youthful Appearance. Time to Feed Your Face with Serum_G
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association ... Featuring a collection of specialty vendors and unique items from across the nation, this ... health and wellness services offered by the VNA. The boutique will be open ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information ... we intend to develop to enable prevention of a major side effect of ... loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label ...
(Date:10/12/2017)... ... 12, 2017 , ... Women-owned and Grand Rapids-based workplace wellness ... in Wellness® by Best and Brightest. OnSite Wellness will be honored at the ... 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, located at ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... EXTON, Pa. , Oct. 10, 2017   ... leader in innovative solutions for injectable drug administration, today ... of West,s ID Adapter for improving the intradermal administration ... the Fourth Skin Vaccination Summit in May 2017 by ... Team Lead, Polio Department, World Health Organization (WHO), and ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
(Date:10/4/2017)...  According to the Centers for Disease Control and Prevention (CDC), ... Urgent Care is helping communities across Massachusetts , ... offering no-cost* flu shots through the end of the month. ... regulations. ... a flu shot is by the end of October, according to the ...
Breaking Medicine Technology: