Navigation Links
Melanoma of the rectum: A rare entity
Date:4/30/2008

Primary anorectal melanoma is a rare and very aggressive disorder. A report published on March 14, 2008, in the World Journal of Gastroenterology addresses such a case. A 41-year-old man presented with a 6-month history of changed defecation and rectal bleeding. A 3-cm polypoid tumor of the lower rectum was found at rectosigmoidoscopy, which proved to be a leiomyosarcoma upon biopsy. Dissemination studies did not show any metastases. He underwent an APR. The histopathology of the specimen showed a melanoma (S-100 stain positive). Two years after the resection, metastases in the abdomen and right lung were found. He died a year and a half later.

In the view of the authors, if there is suspicion of an anorectal sarcoma, one should always perform an S-100 stain following a biopsy. A positive S-100 stain indicates that the tumor is most likely to be a melanoma. Depending on the outcome of the dissemination studies, a surgical resection has to be performed. It has been thought that a sphincter-saving local excision combined with adjuvant locoregional radiotherapy should be preferred in the case of small tumors. The same locoregional control is achieved with less loss of function compared to non-sphincter-saving surgery. Only in the case of large and obstructing tumors is an abdominoperineal resection the treatment of choice.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Melanoma Diagnosis Often Delayed for Rural Poor
2. Melanoma drug revs immune cells but cancer cells ignore it
3. Promising drug combination may help those with ocular melanoma that has spread
4. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
5. Provectus Pharmaceuticals, Inc. releases summary results of phase 1 metastatic melanoma study
6. New type of drug shows promise in attacking melanoma in an innovative way
7. Genes Unlock New Treatments for Deadly Melanoma
8. Top-Line Data Available from Three Ipilimumab Pivotal Trials in Patients with Advanced Metastatic Melanoma
9. Researchers Hone in on Cancer Stem Cells for Melanoma
10. Melanomas may appear noticeably different than other moles
11. Melanomas Present Unique Appearance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... One way ... say anything.” This is unfortunately true. But we toss the baby out with the ... single-page brief provides tips for identifying higher-quality studies and otherwise making better use of ...
(Date:4/28/2016)... ... April 28, 2016 , ... USA Medical Card reminds us that May is National Stroke ... is the fourth leading cause of death in the United States; someone has one every ... of them in individuals under 65 years old. A stroke is when blood flow ...
(Date:4/28/2016)... ... April 28, 2016 , ... Anzu®, ... announced a new Residency Education & Collaboration Platform for hospitals and medical ... and a host of collaboration tools designed to improve patient outcomes through ...
(Date:4/28/2016)... ... 28, 2016 , ... A first-time look at workers’ compensation claims in Kentucky ... Workers Compensation Research Institute (WCRI) announced, and that costs per claim were stable ... 16th Edition , found that indemnity costs per claim and benefit delivery expenses per ...
(Date:4/28/2016)... ... April 28, 2016 , ... Accreditation Commission ... Oncology Pharmacy Association (COPA) to develop a comprehensive Specialty Pharmacy Accreditation with Distinction ... an accreditation distinction. ACHC provides a wide range of pharmacy accreditation services that ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016   Zillion Group today announced ... platform, which specializes in live video consultation. Turning ... products, Zillion enables companies to realize the true ... take control of their health. ... including one-to-one, group and webcast scheduled or on-demand ...
(Date:4/27/2016)... , April 27, 2016  Bayer Animal ... a senior from the University of Florida College ... the Bayer Excellence in Communication Award (BECA). Brittany ... which were awarded a total of $70,000 in ... last four years, Bayer has provided a total ...
(Date:4/27/2016)... April 27, 2016 ... the  "Global Anesthesia Disposables Market 2016-2020"  report ... ) ,The global anesthesia disposables market ... of 4.03% during the period 2016-2020.  ... threat to patients, safety. Organizations like the ...
Breaking Medicine Technology: